(Q36915742)

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Polymyxin Resistance in Acinetobacter baumannii: Genetic Mutations and Transcriptomic Changes in Response to Clinically Relevant Dosage Regimens.

scientific article published on 19 May 2016

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2 April 2020

Polymyxin Resistance in Acinetobacter baumannii: Genetic Mutations and Transcriptomic Changes in Response to Clinically Relevant Dosage Regimens (English)

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2 April 2020

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Acinetobacter baumannii

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2 April 2020

Juergen Bulitta

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2 April 2020

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2 April 2020

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2 April 2020

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2 April 2020

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Brian T Tsuji

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2 April 2020

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Soon-Ee Cheah

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2 April 2020

Matthew D Johnson

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2 April 2020

Alan Forrest

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2 April 2020

Scientific Reports

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2 April 2020

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2 April 2020

26233

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2 April 2020

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19 May 2016

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22 June 2022

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A PmrB-Regulated Deacetylase Required for Lipid A Modification and Polymyxin Resistance in Acinetobacter baumannii

1 reference

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29 September 2017

Colistin Population Pharmacokinetics after Application of a Loading Dose of 9 MU Colistin Methanesulfonate in Critically Ill Patients

1 reference

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29 September 2017

Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two 'old' antibiotics-polymyxin B and chloramphenicol

1 reference

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29 September 2017

limma powers differential expression analyses for RNA-sequencing and microarray studies

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29 September 2017

The transcriptomic response of Acinetobacter baumannii to colistin and doripenem alone and in combination in an in vitro pharmacokinetics/pharmacodynamics model

1 reference

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29 September 2017

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

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29 September 2017

Interaction of drug- and granulocyte-mediated killing of Pseudomonas aeruginosa in a murine pneumonia model

1 reference

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29 September 2017

Colistin and polymyxin B: peas in a pod, or chalk and cheese?

1 reference

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29 September 2017

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29 September 2017

A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity

1 reference

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29 September 2017

Rapid killing of Acinetobacter baumannii by polymyxins is mediated by a hydroxyl radical death pathway

1 reference

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29 September 2017

The combination of colistin and doripenem is synergistic against Klebsiella pneumoniae at multiple inocula and suppresses colistin resistance in an in vitro pharmacokinetic/pharmacodynamic model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

Application of a loading dose of colistin methanesulfonate in critically ill patients: population pharmacokinetics, protein binding, and prediction of bacterial kill

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

The pmrCAB operon mediates polymyxin resistance in Acinetobacter baumannii ATCC 17978 and clinical isolates through phosphoethanolamine modification of lipid A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

Population pharmacokinetics of colistin methanesulfonate and formed colistin in critically ill patients from a multicenter study provide dosing suggestions for various categories of patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

Saturability of granulocyte kill of Pseudomonas aeruginosa in a murine model of pneumonia

1 reference

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29 September 2017

Insertion sequence ISAba11 is involved in colistin resistance and loss of lipopolysaccharide in Acinetobacter baumannii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

Resistance to polymyxins: Mechanisms, frequency and treatment options

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

The population structure of Acinetobacter baumannii: expanding multiresistant clones from an ancestral susceptible genetic pool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

Structure--activity relationships of polymyxin antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

Colistin in the 21st century

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

Resistance to colistin in Acinetobacter baumannii associated with mutations in the PmrAB two-component system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

Population pharmacokinetic analysis of colistin methanesulfonate and colistin after intravenous administration in critically ill patients with infections caused by gram-negative bacteria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872528

29 September 2017

Acinetobacter baumannii: emergence of a successful pathogen

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Alternative mechanisms of action of cationic antimicrobial peptides on bacteria

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29 September 2017

Polymyxin B for the treatment of multidrug-resistant pathogens: a critical review.

1 reference

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29 September 2017

OrthoMCL: Identification of Ortholog Groups for Eukaryotic Genomes

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Inorganic polyphosphate is essential for long-term survival and virulence factors in Shigella and Salmonella spp.

1 reference

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29 September 2017

Contemporary assessment of antimicrobial susceptibility testing methods for polymyxin B and colistin: review of available interpretative criteria and quality control guidelines

1 reference

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29 September 2017

Interactions of bacterial cationic peptide antibiotics with outer and cytoplasmic membranes of Pseudomonas aeruginosa

1 reference

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29 September 2017

Peptide antibiotics.

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29 September 2017

Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii

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Antimicrobial susceptibility of 22746 pathogens from Canadian hospitals: results of the CANWARD 2007-11 study

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27 June 2018

Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus

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Correlation between overexpression and amino acid substitution of the PmrAB locus and colistin resistance in Acinetobacter baumannii.

1 reference

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Comparison of once-, twice- and thrice-daily dosing of colistin on antibacterial effect and emergence of resistance: studies with Pseudomonas aeruginosa in an in vitro pharmacodynamic model.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/27195897

12 December 2020

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2 April 2020

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