(Q36917813)

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A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo

scientific article published on 19 February 2016

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scholarly article

1 reference

Europe PubMed Central

17 August 2017

A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo (English)

1 reference

Europe PubMed Central

17 August 2017

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neoplastic stem cells

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

object named as

Stephen C Mack

5

0 references

Roger E McLendon

8

object named as

Roger E McLendon

1 reference

Europe PubMed Central

17 August 2017

10

object named as

Jeremy N Rich

1 reference

Europe PubMed Central

17 August 2017

author name string

Christopher G Hubert

1

1 reference

Europe PubMed Central

17 August 2017

Maricruz Rivera

2

1 reference

Europe PubMed Central

17 August 2017

Lisa C Spangler

3

1 reference

Europe PubMed Central

17 August 2017

Qiulian Wu

4

1 reference

Europe PubMed Central

17 August 2017

Briana C Prager

6

1 reference

Europe PubMed Central

17 August 2017

Marta Couce

7

1 reference

Europe PubMed Central

17 August 2017

Andrew E Sloan

9

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Europe PubMed Central

17 August 2017

language of work or name

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publication date

19 February 2016

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Europe PubMed Central

17 August 2017

Cancer Research

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Europe PubMed Central

17 August 2017

76

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Europe PubMed Central

17 August 2017

8

1 reference

Europe PubMed Central

17 August 2017

2465-2477

1 reference

Europe PubMed Central

17 August 2017

Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity

1 reference

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Organoid models of human and mouse ductal pancreatic cancer

1 reference

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Three-dimensional organotypic culture: experimental models of mammalian biology and disease

1 reference

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Organoid cultures derived from patients with advanced prostate cancer

1 reference

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Identification of multipotent luminal progenitor cells in human prostate organoid cultures

1 reference

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Generation of cerebral organoids from human pluripotent stem cells

1 reference

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Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

1 reference

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Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy

1 reference

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Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells

1 reference

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Cerebral organoids model human brain development and microcephaly

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Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake.

1 reference

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Glioblastoma: from molecular pathology to targeted treatment

1 reference

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Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth.

1 reference

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Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ.

1 reference

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1 reference

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The nuclear receptor TLX is required for gliomagenesis within the adult neurogenic niche

1 reference

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SRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells

1 reference

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Deadly teamwork: neural cancer stem cells and the tumor microenvironment

1 reference

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Control of the embryonic stem cell state

1 reference

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The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma

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Oxygen in stem cell biology: a critical component of the stem cell niche

1 reference

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Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres

1 reference

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A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha

1 reference

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The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation

1 reference

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Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells

1 reference

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Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal

1 reference

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Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth

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Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

1 reference

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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

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Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma

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Identifiers

10.1158/0008-5472.CAN-15-2402

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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