(Q36919661)

English

Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels

scientific article published on 05 April 2013

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scholarly article

1 reference

Europe PubMed Central

17 August 2017

Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels (English)

1 reference

Europe PubMed Central

17 August 2017

object named as

Philipp Sasse

4

0 references

object named as

Mario Delmar

18

0 references

Stefan Offermanns

object named as

Stefan Offermanns

16

0 references

author name string

Indra Lübkemeier

1

1 reference

Europe PubMed Central

17 August 2017

Robert Pascal Requardt

2

1 reference

Europe PubMed Central

17 August 2017

Xianming Lin

3

1 reference

Europe PubMed Central

17 August 2017

René Andrié

5

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Europe PubMed Central

17 August 2017

Jan Wilko Schrickel

6

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Europe PubMed Central

17 August 2017

Halina Chkourko

7

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Europe PubMed Central

17 August 2017

Feliksas F Bukauskas

8

1 reference

Europe PubMed Central

17 August 2017

Jung-Sun Kim

9

1 reference

Europe PubMed Central

17 August 2017

Marina Frank

10

1 reference

Europe PubMed Central

17 August 2017

Daniela Malan

11

1 reference

Europe PubMed Central

17 August 2017

Jiong Zhang

12

1 reference

Europe PubMed Central

17 August 2017

Angela Wirth

13

1 reference

Europe PubMed Central

17 August 2017

Radoslaw Dobrowolski

14

1 reference

Europe PubMed Central

17 August 2017

Peter J Mohler

15

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Europe PubMed Central

17 August 2017

Bernd K Fleischmann

17

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Europe PubMed Central

17 August 2017

Klaus Willecke

19

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Europe PubMed Central

17 August 2017

publication date

5 April 2013

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Europe PubMed Central

17 August 2017

Basic Research in Cardiology

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Europe PubMed Central

17 August 2017

108

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17 August 2017

3

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Europe PubMed Central

17 August 2017

348

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Europe PubMed Central

17 August 2017

https://scigraph.springernature.com/pub.10.1007/s00395-013-0348-y

0 references

Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Cx43 associates with Na(v)1.5 in the cardiomyocyte perinexus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Desmosome-ion channel interactions and their possible role in arrhythmogenic cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Remodeling of mechanical junctions and of microtubule-associated proteins accompany cardiac connexin43 lateralization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Connexin43 modulates cell polarity and directional cell migration by regulating microtubule dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Functional consequences of abnormal Cx43 expression in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Subcellular heterogeneity of sodium current properties in adult cardiac ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Interactions between ankyrin-G, Plakophilin-2, and Connexin43 at the cardiac intercalated disc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Cortactin is required for N-cadherin regulation of Kv1.5 channel function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

A peptide mimetic of the connexin43 carboxyl terminus reduces gap junction remodeling and induced arrhythmia following ventricular injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Gap junction permeability: selectivity for anionic and cationic probes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Tubulin polymerization modifies cardiac sodium channel expression and gating

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Loss of plakophilin-2 expression leads to decreased sodium current and slower conduction velocity in cultured cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Cx43 CT domain influences infarct size and susceptibility to ventricular tachyarrhythmias in acute myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Structural and molecular mechanisms of gap junction remodeling in epicardial border zone myocytes following myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Permeability of homotypic and heterotypic gap junction channels formed of cardiac connexins mCx30.2, Cx40, Cx43, and Cx45.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Gating properties of heterotypic gap junction channels formed of connexins 40, 43, and 45.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Dynamic model for ventricular junctional conductance during the cardiac action potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Defective epidermal barrier in neonatal mice lacking the C-terminal region of connexin43.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Gap junction channel gating

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Localization of sodium channels in intercalated disks modulates cardiac conduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Null mutation of connexin43 causes slow propagation of ventricular activation in the late stages of mouse embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Loss of annexin A7 leads to alterations in frequency-induced shortening of isolated murine cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Voltage clamp of the cardiac sodium current at 37 degrees C in physiologic solutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

Cardiac malformation in neonatal mice lacking connexin43.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

29 September 2017

G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

27 June 2018

Connexin43 and the regulation of intercalated disc function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

27 June 2018

The carboxy terminal domain of connexin43: from molecular regulation of the gap junction channel to supramolecular organization of the intercalated disk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

27 June 2018

Quantification of spatial inhomogeneity in conduction and initiation of reentrant atrial arrhythmias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

27 June 2018

Membrane topology and quaternary structure of cardiac gap junction ion channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

27 June 2018

A new diagnostic test for arrhythmogenic right ventricular cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

4 September 2018

C-terminal truncation of connexin43 changes number, size, and localization of cardiac gap junction plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

4 September 2018

The area composita of adhering junctions connecting heart muscle cells of vertebrates - III: assembly and disintegration of intercalated disks in rat cardiomyocytes growing in culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

4 September 2018

Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

4 September 2018

Functional role of connexin43 gap junction channels in adult mouse heart assessed by inducible gene deletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3678986

4 September 2018

Connexin43 regulates sodium current; ankyrin-G modulates gap junctions: the intercalated disc exchanger

1 reference

https://pubmed.ncbi.nlm.nih.gov/23558439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced content of connexin43 gap junctions in ventricular myocardium from hypertrophied and ischemic human hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/23558439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remodeling of myocyte gap junctions in arrhythmogenic right ventricular cardiomyopathy due to a deletion in plakoglobin (Naxos disease)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23558439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiomyocyte-restricted deletion of connexin43 during mouse development

1 reference

https://pubmed.ncbi.nlm.nih.gov/23558439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the pH-dependent Interaction between the Gap Junction Protein Connexin43 Carboxyl Terminus and Cytoplasmic Loop Domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/23558439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced heterogeneity of myocardial conduction and severe cardiac electrical instability in annexin A7-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23558439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00395-013-0348-Y

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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