(Q36926511)

17 August 2017

The diphthamide modification on elongation factor-2 renders mammalian cells resistant to ricin (English)

1 reference

National Institute of Allergy and Infectious Diseases

17 August 2017

1 reference

https://app.dimensions.ai/details/publication/pub.1012625153

1 January 2019

4

Stephen H Leppla

National Institute of Allergy and Infectious Diseases

1 reference

17 August 2017

2

Shihui Liu

1 reference

17 August 2017

Pradeep K Gupta

1

1 reference

PMCID

2562939

17 August 2017

Mariska P Batavia

series ordinal

3

1 reference

17 August 2017

5 May 2008

1 reference

PMCID

2562939

full work available at URL

17 August 2017

https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1462-5822.2008.01159.x

language of work or name

English

0 references

published in

Cellular Microbiology

1 reference

17 August 2017

10

1 reference

17 August 2017

8

1 reference

17 August 2017

1687-1694

1 reference

Characterization of the interaction between anthrax toxin and its cellular receptors

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Immunotoxin treatment of cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Translation elongation factor 2 anticodon mimicry domain mutants affect fidelity and diphtheria toxin resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Dph3, a small protein required for diphthamide biosynthesis, is essential in mouse development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

An early step in wobble uridine tRNA modification requires the Elongator complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Antiviral activity of ribosome inactivating proteins in medicine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Ovca1 regulates cell proliferation, embryonic development, and tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Retroviral insertional mutagenesis identifies a small protein required for synthesis of diphthamide, the target of bacterial ADP-ribosylating toxins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Anthrax toxin: structures, functions and tumour targeting

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Ribosome-inactivating proteins from plants: more than RNA N-glycosidases?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Diphthamide synthesis in Saccharomyces cerevisiae: structure of the DPH2 gene.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Ribosome-inactivating proteins from plants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Pseudomonas exotoxin-mediated selection yields cells with altered expression of low-density lipoprotein receptor-related protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Posttranslational modification of elongation factor 2 in diphtheria-toxin-resistant mutants of CHO-K1 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

In vitro biosynthesis of diphthamide, studied with mutant Chinese hamster ovary cells resistant to diphtheria toxin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Occurrence of diphthamide in archaebacteria.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Diphtheria toxin-resistant mutants of Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Biosynthesis of diphthamide in Saccharomyces cerevisiae. Partial purification and characterization of a specific S-adenosylmethionine:elongation factor 2 methyltransferase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Protein toxin inhibitors of protein synthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

DPH5, a methyltransferase gene required for diphthamide biosynthesis in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Saccharomyces cerevisiae elongation factor 2. Mutagenesis of the histidine precursor of diphthamide yields a functional protein that is resistant to diphtheria toxin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Effect of alpha-sarcin and ribosome-inactivating proteins on the interaction of elongation factors with ribosomes

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562939

Site-specific mutagenesis of the histidine precursor of diphthamide in the human elongation factor-2 gene confers resistance to diphtheria toxin.

27 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2008.01159.X

Protective Effect of Elongation Factor 2 on the Inactivation of Ribosomes by the Toxic Lectins Abrin and Ricin

21 January 2018

1 reference

12 December 2020

Characterization of the diphtheria toxin-resistance system in Chinese hamster ovary cells

1 reference

12 December 2020

Diphtheria toxin. Site and configuration of ADP-ribosylation of diphthamide in elongation factor 2

1 reference

12 December 2020

Diphthamide in elongation factor 2: ADP-ribosylation, purification, and properties

1 reference

12 December 2020

Elongation factor 2 mutants deficient in diphthamide formation show temperature-sensitive cell growth

1 reference

12 December 2020

Interaction sites of ribosome-bound eukaryotic elongation factor 2 in 18S and 28S rRNA

1 reference

12 December 2020

10.1111/J.1462-5822.2008.01159.X

Identifiers

DOI

1 reference

10.1111/J.1462-5822.2008.01159.X

17 August 2017

0 references

Dimensions Publication ID

1012625153

1 reference

https://app.dimensions.ai/details/publication/pub.1012625153

1 January 2019

1 reference

17 August 2017

1 reference

PMCID

2562939