(Q36941983)

17 August 2017

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title

G protein-coupled receptor oligomerization provides the framework for signal discrimination (English)

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G protein-coupled receptor

17 August 2017

main subject

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author name string

Roberto Maggio

series ordinal

1

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17 August 2017

Giulio Innamorati

series ordinal

2

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17 August 2017

Marco Parenti

series ordinal

3

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17 August 2017

language of work or name

English

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publication date

14 September 2007

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Journal of Neurochemistry

17 August 2017

published in

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17 August 2017

volume

103

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17 August 2017

issue

5

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17 August 2017

page(s)

1741-1752

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Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons.

17 August 2017

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Integrins regulate opioid receptor signaling in trigeminal ganglion neurons

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A bivalent ligand (KDN-21) reveals spinal delta and kappa opioid receptors are organized as heterodimers that give rise to delta(1) and kappa(2) phenotypes. Selective targeting of delta-kappa heterodimers

21 January 2018

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Recent developments in constitutive receptor activity and inverse agonism, and their potential for GPCR drug discovery

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beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation

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A bivalent ligand (KDAN-18) containing delta-antagonist and kappa-agonist pharmacophores bridges delta2 and kappa1 opioid receptor phenotypes

21 January 2018

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Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties

21 January 2018

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G-protein-coupled receptor oligomerization and its potential for drug discovery

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21 January 2018

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Dimerization of cell surface receptors in signal transduction

21 January 2018

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Inhibition of serotonin 5-hydroxytryptamine2c receptor function through heterodimerization: receptor dimers bind two molecules of ligand and one G-protein

21 January 2018

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G-protein-independent signaling by G-protein-coupled receptors

21 January 2018

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Evidence for cross‐talk between M2 and M3 muscarinic acetylcholine receptors in the regulation of second messenger and extracellular signal‐regulated kinase signalling pathways in Chinese hamster ovary cells

21 January 2018

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The melanosomal/lysosomal protein OA1 has properties of a G protein-coupled receptor

21 January 2018

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Pharmacological characterization and cross talk of alpha1a- and alpha1b-adrenoceptors coexpressed in human embryonic kidney 293 cells

21 January 2018

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Identification and structural determination of the M(3) muscarinic acetylcholine receptor basolateral sorting signal

21 January 2018

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G-protein-coupled receptor heterodimerization modulates receptor function

21 January 2018

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The patch clamp technique in ion channel research

21 January 2018

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Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk?

21 January 2018

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Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.

21 January 2018

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Opsin is present as dimers in COS1 cells: identification of amino acids at the dimeric interface

21 January 2018

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The 2.0 A crystal structure of a heterotrimeric G protein

21 January 2018

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Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal

21 January 2018

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Historical review: a brief history and personal retrospective of seven-transmembrane receptors

21 January 2018

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Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases

21 January 2018

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Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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G-protein signaling: back to the future

21 January 2018

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Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation.

21 January 2018

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Chemokine receptor homo- or heterodimerization activates distinct signaling pathways

21 January 2018

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The role of Ca2+/calmodulin-stimulable adenylyl cyclases as molecular coincidence detectors in memory formation

21 January 2018

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Heterotrimeric G proteins: organizers of transmembrane signals

21 January 2018

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21 January 2018

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An amino-acid taste receptor

21 January 2018

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The paired activation of the two components of the muscarinic M3 receptor dimer is required for induction of ERK1/2 phosphorylation

21 January 2018

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Paired activation of two components within muscarinic M3 receptor dimers is required for recruitment of beta-arrestin-1 to the plasma membrane

21 January 2018

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Crystal structure of rhodopsin: A G protein-coupled receptor

21 January 2018

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Oligomeric potential of the M2 muscarinic cholinergic receptor

21 January 2018

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Oligomerization of G protein-coupled receptors: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Targeting dopamine D2 and cannabinoid-1 (CB1) receptors in rat nucleus accumbens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Heterodimerization of g protein-coupled receptors: specificity and functional significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling

21 January 2018

1 reference

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Receptor heterodimerization leads to a switch in signaling: beta-arrestin2-mediated ERK activation by mu-delta opioid receptor heterodimers

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Basal opioid receptor activity, neutral antagonists, and therapeutic opportunities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Biochemical characterization of beta2-adrenergic receptor dimers and oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

cAMP evokes long-term facilitation in Aplysia sensory neurons that requires new protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Caveolins, liquid-ordered domains, and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Crystal structure of a G-protein beta gamma dimer at 2.1A resolution

21 January 2018

1 reference

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Roles of G-protein-coupled receptor dimerization

21 January 2018

1 reference

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Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

G-Protein-coupled receptor-protein interactions: basis for new concepts on receptor structure and function

21 January 2018

1 reference

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Cross talk between P2Y2 nucleotide receptors and CXC chemokine receptor 2 resulting in enhanced Ca2+ signaling involves enhancement of phospholipase C activity and is enabled by incremental Ca2+ release in human embryonic kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Interaction of bivalent ligand KDN21 with heterodimeric delta-kappa opioid receptors in human embryonic kidney 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Localization of the kappa opioid receptor in lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Compartmentalisation of cAMP and Ca(2+) signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

Rhodopsin dimers in native disc membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04896.X

10.1111/J.1471-4159.2007.04896.X

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference