(Q36943713)

English

Forkhead transcription factors (FoxOs) promote apoptosis of insulin-resistant macrophages during cholesterol-induced endoplasmic reticulum stress

scientific article published on 26 August 2008

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scholarly article

1 reference

Europe PubMed Central

17 August 2017

Forkhead transcription factors (FoxOs) promote apoptosis of insulin-resistant macrophages during cholesterol-induced endoplasmic reticulum stress (English)

1 reference

Europe PubMed Central

17 August 2017

endoplasmic reticulum

0 references

1 reference

based on heuristic

inferred from title

insulin resistance

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

Domenico Accili

9

object named as

Domenico Accili

1 reference

Europe PubMed Central

17 August 2017

Tracie A. Seimon

3

object named as

Tracie A Seimon

1 reference

Europe PubMed Central

17 August 2017

author name string

Takafumi Senokuchi

1

1 reference

Europe PubMed Central

17 August 2017

Chien-Ping Liang

2

1 reference

Europe PubMed Central

17 August 2017

Seongah Han

4

1 reference

Europe PubMed Central

17 August 2017

Michihiro Matsumoto

5

1 reference

Europe PubMed Central

17 August 2017

Alexander S Banks

6

1 reference

Europe PubMed Central

17 August 2017

Ji-Hye Paik

7

1 reference

Europe PubMed Central

17 August 2017

Ronald A DePinho

8

1 reference

Europe PubMed Central

17 August 2017

Ira Tabas

10

1 reference

Europe PubMed Central

17 August 2017

Alan R Tall

11

1 reference

Europe PubMed Central

17 August 2017

language of work or name

0 references

publication date

26 August 2008

1 reference

Europe PubMed Central

17 August 2017

number of pages

10

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

17 August 2017

57

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Europe PubMed Central

17 August 2017

2967-2976

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Europe PubMed Central

17 August 2017

11

1 reference

Europe PubMed Central

17 August 2017

Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease

1 reference

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Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications

1 reference

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29 September 2017

A Foxo/Notch pathway controls myogenic differentiation and fiber type specification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

ER stress triggers apoptosis by activating BH3-only protein Bim

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

The macrophage at the crossroads of insulin resistance and atherosclerosis

1 reference

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29 September 2017

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages.

1 reference

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29 September 2017

Endoplasmic reticulum stress signaling in disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism

1 reference

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29 September 2017

Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Increased CD36 protein as a response to defective insulin signaling in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Cell cycle and death control: long live Forkheads

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Multiple CHD risk factors in type 2 diabetes: beyond hyperglycaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Insulin resistance and cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

A new member of the I kappaB protein family, I kappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

Macrophages and atherosclerotic plaque stability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

29 September 2017

The unfolded protein response is an important regulator of inflammatory genes in endothelial cells

1 reference

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27 June 2018

Pioglitazone increases macrophage apoptosis and plaque necrosis in advanced atherosclerotic lesions of nondiabetic low-density lipoprotein receptor-null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

4 September 2018

Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

4 September 2018

Effect of ACAT inhibition on the progression of coronary atherosclerosis

1 reference

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4 September 2018

Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

4 September 2018

Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice

1 reference

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Morphologic findings of coronary atherosclerotic plaques in diabetics: a postmortem study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

4 September 2018

The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

4 September 2018

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570393

4 September 2018

Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a

1 reference

https://pubmed.ncbi.nlm.nih.gov/18728232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of NFkappaB in activated rat hepatic stellate cells by proteasome inhibitors and an IkappaB super-repressor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18728232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central role of the scaffold protein tumor necrosis factor receptor-associated factor 2 in regulating endoplasmic reticulum stress-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18728232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18728232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pivotal Advance: Macrophages become resistant to cholesterol-induced death after phagocytosis of apoptotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18728232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB08-0520

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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