(Q36946557)

17 August 2017

Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla (English)

1 reference

17 August 2017

0 references

Kristin A Hogquist

4

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author name string

Tom M McCaughtry

series ordinal

1

1 reference

17 August 2017

Troy A Baldwin

series ordinal

2

1 reference

17 August 2017

Matthew S Wilken

series ordinal

3

1 reference

17 August 2017

language of work or name

English

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publication date

20 October 2008

1 reference

Journal of Experimental Medicine

17 August 2017

1 reference

17 August 2017

205

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17 August 2017

2575-2584

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17 August 2017

11

1 reference

describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2571932/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Generating intrathymic microenvironments to establish T-cell tolerance.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

A constant affinity threshold for T cell tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Impaired responsiveness to T-cell receptor stimulation and defective negative selection of thymocytes in CCR7-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Developmental regulation of Foxp3 expression during ontogeny.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Central tolerance: learning self-control in the thymus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

The timing of TCR alpha expression critically influences T cell development and selection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Dependence of self-tolerance on TRAF6-directed development of thymic stroma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Detection of apoptosis in tissue sections.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Thymus epithelium induces tissue-specific tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Lymphocytes selected in allogeneic thymic epithelium mediate dominant tolerance toward tissue grafts of the thymic epithelium haplotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

An essential role for gp39, the ligand for CD40, in thymic selection.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Deletion of high-avidity T cells by thymic epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Induction of tolerance by embryonic thymic epithelial grafts in birds and mammals

29 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

29 September 2017

https://api.crossref.org/works/10.1084%2FJEM.20080866

TCR signaling regulates thymic organization: lessons from TCR-transgenic mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Negative selection of precursor thymocytes before their differentiation into CD4+CD8+ cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Rat Thymic Epithelium Positively Selects Mouse T Cells with Specificity for Rat MHC Class II Antigens but Fails to Induce Detectable Tolerance in the Mouse T Cells to the Rat MHC Antigens

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Developmental alterations in thymocyte sensitivity are actively regulated by MHC class II expression in the thymic medulla

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Negative selection of the T-cell repertoire: where and when does it occur?

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

CCR7 signals are essential for cortex-medulla migration of developing thymocytes.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

The influence of the thymic environment on the CD4-versus-CD8 T lineage decision.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Thymocyte apoptosis induced by T cell activation is mediated by glucocorticoids in vivo

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Early TCRalpha expression generates TCRalphagamma complexes that signal the DN-to-DP transition and impair development.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Direct Visualization of thymocyte apoptosis in neglect, acute and steady-state negative selection

4 September 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080866

Minor but not major histocompatibility antigens of thymus epithelium tolerize precursors of cytolytic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080866

Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080866

Thymic epithelium and the induction of transplantation tolerance in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080866

T-cell apoptosis detected in situ during positive and negative selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080866

Thymic cortical epithelium induces self tolerance

21 January 2018

1 reference

12 December 2020

Altered thymocyte development resulting from expressing a deleting ligand on selecting thymic epithelium

1 reference

12 December 2020

Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation

1 reference

12 December 2020

Dissociation of thymic positive and negative selection in transgenic mice expressing major histocompatibility complex class I molecules exclusively on thymic cortical epithelial cells

1 reference

12 December 2020

Premature TCR alpha beta expression and signaling in early thymocytes impair thymocyte expansion and partially block their development

1 reference

12 December 2020

Central tolerance to self-antigen expressed by cortical epithelial cells

1 reference

12 December 2020

Tolerogenicity of thymic epithelium

1 reference

12 December 2020

Selection of the T-cell repertoire in transgenic mice expressing a transplantation antigen in distinct thymus subsets

1 reference

12 December 2020

Anergy induced by thymic medullary epithelium

1 reference

12 December 2020

CD40 is functionally expressed on human thymic epithelial cells

1 reference

12 December 2020

Normal sequence of phenotypic transitions in one cohort of 5-bromo-2'-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression

1 reference

12 December 2020

The costimulatory molecule B7 is expressed in the medullary region of the murine thymus

1 reference

12 December 2020

Antigen-specific and nonspecific deletion of immature cortical thymocytes caused by antigen injection

1 reference

12 December 2020

Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance

1 reference

12 December 2020

Transcriptional analysis of clonal deletion in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20080866

1 reference

17 August 2017

1 reference

17 August 2017

1 reference