(Q36948127)

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The Val158Met polymorphism of the COMT gene is associated with increased pain sensitivity in morphine-treated patients undergoing a painful procedure after cardiac surgery.

scientific article published on June 2013

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210659%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

The Val158Met polymorphism of the COMT gene is associated with increased pain sensitivity in morphine-treated patients undergoing a painful procedure after cardiac surgery (English)

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Europe PubMed Central

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19 February 2020

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19 February 2020

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Dick Tibboel

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19 February 2020

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Sabine J G M Ahlers

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19 February 2020

Laura van Gulik

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19 February 2020

Ron H van Schaik

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19 February 2020

Eric P A van Dongen

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19 February 2020

Peter Bruins

6

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19 February 2020

Catherijne A J Knibbe

8

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19 February 2020

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1 June 2013

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19 February 2020

British Journal of Clinical Pharmacology

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19 February 2020

75

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19 February 2020

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19 February 2020

1506-1515

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19 February 2020

Efficacy of an intravenous bolus of morphine 2.5 versus morphine 7.5 mg for procedural pain relief in postoperative cardiothoracic patients in the intensive care unit: a randomised double-blind controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Pain genetics: past, present and future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

The catechol-O-methyltransferase (COMT) val158met polymorphism affects brain responses to repeated painful stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Genetic basis of pain variability: recent advances

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Pharmacogenetics and postoperative pain: a new approach to improve acute pain management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Predictors of postoperative pain and analgesic consumption: a qualitative systematic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Increased sensitivity to thermal pain following a single opiate dose is influenced by the COMT val(158)met polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Comparison of different pain scoring systems in critically ill patients in a general ICU.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Genetic factors in pain and its treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Sex differences in pain and analgesia: the role of gonadal hormones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

A highly significant association between a COMT haplotype and schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Evaluation of pain in the critically ill patient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Clinical significance of reported changes in pain severity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Human liver catechol-O-methyltransferase pharmacogenetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

29 September 2017

Influence from genetic variability on opioid use for cancer pain: a European genetic association study of 2294 cancer pain patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

Improved analgesia after the realisation of a pain management programme in ICU patients after cardiac surgery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

Predictors of acute postoperative pain after elective surgery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

Prediction of post-operative pain after a laparoscopic tubal ligation procedure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

Patients' self-report of procedural pain in the intensive care unit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

Management of pain in cardiac surgery ICU patients: have we improved over time?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

Sex-related psychological predictors of baseline pain perception and analgesic responses to pentazocine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

Population variation in linkage disequilibrium across the COMT gene considering promoter region and coding region variation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

Patients' perceptions and responses to procedural pain: results from Thunder Project II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

Characterization and implications of estrogenic down-regulation of human catechol-O-methyltransferase gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690109

4 September 2018

Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli

1 reference

https://pubmed.ncbi.nlm.nih.gov/23210659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of pain: Patient preference does not confound pain measurement

1 reference

https://pubmed.ncbi.nlm.nih.gov/23210659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The measurement of clinical pain intensity: a comparison of six methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/23210659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic basis for individual variations in pain perception and the development of a chronic pain condition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23210659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/BCP.12052

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210659%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PMC publication ID

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Europe PubMed Central

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19 February 2020

PubMed publication ID

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Europe PubMed Central

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19 February 2020

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