(Q36955365)

English

Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues

scientific article published on 14 July 2008

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scholarly article

1 reference

Europe PubMed Central

17 August 2017

Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues (English)

1 reference

Europe PubMed Central

17 August 2017

7

object named as

Bruce Caterson

1 reference

Europe PubMed Central

17 August 2017

Clare E. Hughes

object named as

Clare E Hughes

6

0 references

Christopher B Little

object named as

Christopher B Little

8

0 references

1

object named as

James Melrose

1 reference

Europe PubMed Central

17 August 2017

author name string

Emily S Fuller

2

1 reference

Europe PubMed Central

17 August 2017

Peter J Roughley

3

1 reference

Europe PubMed Central

17 August 2017

Margaret M Smith

4

1 reference

Europe PubMed Central

17 August 2017

Briedgeen Kerr

5

1 reference

Europe PubMed Central

17 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

14 July 2008

1 reference

Europe PubMed Central

17 August 2017

Arthritis Research and Therapy

1 reference

Europe PubMed Central

17 August 2017

10

1 reference

Europe PubMed Central

17 August 2017

4

1 reference

Europe PubMed Central

17 August 2017

R79

1 reference

Europe PubMed Central

17 August 2017

https://scigraph.springernature.com/pub.10.1186/ar2453

0 references

Biglycan and fibromodulin fragmentation correlates with temporal and spatial annular remodelling in experimentally injured ovine intervertebral discs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Differential expression of the keratan sulphate proteoglycan, keratocan, during chick corneal embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

The structure and function of cartilage proteoglycans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Biomarkers in spondyloarthritis

1 reference

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29 September 2017

The burden of musculoskeletal disease--a global perspective

1 reference

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29 September 2017

Biologic markers and disc degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Usurped SLRPs: novel arthritis biomarkers exposed by catabolism of small leucine-rich proteoglycans?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Use of biochemical markers to study and follow patients with osteoarthritis

1 reference

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29 September 2017

Direct and indirect markers of cartilage metabolism in synovial fluid obtained from dogs with hip dysplasia and correlation with clinical and radiographic variables

1 reference

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29 September 2017

Matrix metalloproteinases (MMPs) in health and disease: an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Molecular markers of cartilage breakdown and synovitis at baseline as predictors of structural progression of hip osteoarthritis. The ECHODIAH Cohort

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

In vitro, ex vivo, and in vivo methodological approaches for studying therapeutic targets of osteoporosis and degenerative joint diseases: how biomarkers can assist?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Osteoarthritis: socioeconomic problems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

MMPs and ADAMTSs: functional studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Burden of major musculoskeletal conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Cleavage of fibromodulin in cartilage explants involves removal of the N-terminal tyrosine sulfate-rich region by proteolysis at a site that is sensitive to matrix metalloproteinase-13.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Functions of lumican and fibromodulin: lessons from knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Biglycan knockout mice: new models for musculoskeletal diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Elasticity in extracellular matrix 'shape modules' of tendon, cartilage, etc. A sliding proteoglycan-filament model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Age-related changes in the proteoglycans of human skin. Specific cleavage of decorin to yield a major catabolic fragment in adult skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Articular cartilage and changes in arthritis: matrix degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Changes in leucine-rich repeat proteoglycans during maturation of the bovine growth plate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Fibromodulin-null mice have abnormal collagen fibrils, tissue organization, and altered lumican deposition in tendon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Degradation of decorin by matrix metalloproteinases: identification of the cleavage sites, kinetic analyses and transforming growth factor-beta1 release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Changes with age in the structure of fibromodulin in human articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Non-proteoglycan forms of biglycan increase with age in human articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Cartilage proteoglycans: structure and potential functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Ultrastructure of normal and torn menisci of the human knee joint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

The ultrastructure and biochemistry of meniscal cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Pathology of the meniscus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

29 September 2017

Presence of pro-forms of decorin and biglycan in human articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

27 June 2018

Identification and characterization of glycanated and non-glycanated forms of biglycan and decorin in the human intervertebral disc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

27 June 2018

The cleavage of biglycan by aggrecanases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Direct and indirect costs attributable to osteoarthritis in active subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Cartilage elasticity resides in shape module decoran and aggrecan sumps of damping fluid: implications in osteoarthrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Serum cartilage oligomeric matrix protein and other biomarker profiles in tibiofemoral and patellofemoral osteoarthritis of the knee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

The economic burden of disabling hip and knee osteoarthritis (OA) from the perspective of individuals living with this condition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Health-related and overall quality of life of patients with chronic hip and knee complaints in general practice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Accelerated osteoarthritis in the temporomandibular joint of biglycan/fibromodulin double-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Analysis of cartilage biomarkers in the early phases of canine experimental osteoarthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Ocular and scleral alterations in gene-targeted lumican-fibromodulin double-null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Resistance of small leucine-rich repeat proteoglycans to proteolytic degradation during interleukin-1-stimulated cartilage catabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Age-related changes in the structure of the keratan sulphate chains attached to fibromodulin isolated from articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575625

4 September 2018

Mice deficient in biglycan and fibromodulin as a model for temporomandibular joint osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of the utility of biomarkers of osteoarthritis in the guinea pig

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SLRP interaction can protect collagen fibrils from cleavage by collagenases

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in the synthesis and mRNA expression of decorin and aggrecan in human meniscus and articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early changes in lapine menisci during osteoarthritis development: Part I: cellular and matrix alterations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal collagen fibrils in tendons of biglycan/fibromodulin-deficient mice lead to gait impairment, ectopic ossification, and osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A syndrome of joint laxity and impaired tendon integrity in lumican- and fibromodulin-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic compression of cartilage/bone explants in vitro leads to physical weakening, mechanical breakdown of collagen and release of matrix fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Keratocan-deficient mice display alterations in corneal structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathology of the degenerate meniscus lesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of small proteoglycan fragments in normal and arthritic human cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in the expression of decorin and biglycan in human articular cartilage with age and regulation by TGF-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large and small proteoglycans of osteoarthritic and rheumatoid articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in messenger RNA and protein levels of proteoglycans and link protein in human osteoarthritic cartilage samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in fibromodulin and lumican in human intervertebral discs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of keratan sulfate synthesis on lumican by the action of cytokines on human articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of Decorin and Biglycan on Mechanical Properties of Multiple Tendons in Knockout Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18620607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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