(Q36962785)

English

Smad2 functions as a co-activator of canonical Wnt/beta-catenin signaling pathway independent of Smad4 through histone acetyltransferase activity of p300.

scientific article published on 18 May 2008

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scholarly article

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9 January 2020

Smad2 functions as a co-activator of canonical Wnt/beta-catenin signaling pathway independent of Smad4 through histone acetyltransferase activity of p300 (English)

1 reference

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9 January 2020

Tadahiro Nagaoka

7

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9 January 2020

9

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9 January 2020

author name string

Morihisa Hirota

1

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9 January 2020

Kazuhide Watanabe

2

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9 January 2020

Shin Hamada

3

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9 January 2020

Youping Sun

4

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9 January 2020

Luigi Strizzi

5

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9 January 2020

Mario Mancino

6

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9 January 2020

Monica Gonzales

8

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9 January 2020

Caterina Bianco

10

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9 January 2020

David S Salomon

11

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9 January 2020

publication date

18 May 2008

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9 January 2020

number of pages

10

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Cellular Signalling

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9 January 2020

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9 January 2020

1632-1641

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9 January 2020

9

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9 January 2020

Requirement of glycosylphosphatidylinositol anchor of Cripto-1 for trans activity as a Nodal co-receptor.

1 reference

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Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis

1 reference

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29 September 2017

The Wnt signal transduction pathway in stem cells and cancer cells: influence on cellular invasion.

1 reference

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29 September 2017

Wnt pathway and breast cancer

1 reference

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A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling

1 reference

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29 September 2017

Nodal signaling: developmental roles and regulation.

1 reference

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29 September 2017

Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis

1 reference

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29 September 2017

The many ways of Wnt in cancer

1 reference

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29 September 2017

Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness.

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29 September 2017

Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors

1 reference

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29 September 2017

Wnt/beta-catenin signaling and body plan formation in mouse embryos

1 reference

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29 September 2017

Cripto-1: an oncofetal gene with many faces

1 reference

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29 September 2017

TGF beta-induced focal complex formation in epithelial cells is mediated by activated ERK and JNK MAP kinases and is independent of Smad4.

1 reference

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29 September 2017

Duel nature of TGF-beta signaling: tumor suppressor vs. tumor promoter

1 reference

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29 September 2017

Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and beta-catenin

1 reference

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29 September 2017

An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells

1 reference

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29 September 2017

The Wnt signaling pathway in development and disease

1 reference

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29 September 2017

The murine gastrin promoter is synergistically activated by transforming growth factor-beta/Smad and Wnt signaling pathways

1 reference

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29 September 2017

Cripto-1 overexpression leads to enhanced invasiveness and resistance to anoikis in human MCF-7 breast cancer cells

1 reference

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29 September 2017

Smad4 and β-Catenin Co-activators Functionally Interact with Lymphoid-enhancing Factor to Regulate Graded Expression of Msx2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2578836

29 September 2017

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

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29 September 2017

Caught up in a Wnt storm: Wnt signaling in cancer

1 reference

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29 September 2017

HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells

1 reference

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29 September 2017

Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcription

1 reference

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29 September 2017

Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4

1 reference

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29 September 2017

Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study.

1 reference

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Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling

1 reference

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The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.

1 reference

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29 September 2017

TGFbeta signaling in growth control, cancer, and heritable disorders

1 reference

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29 September 2017

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways

1 reference

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29 September 2017

The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates

1 reference

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1 reference

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Biochemical analysis of distinct activation functions in p300 that enhance transcription initiation with chromatin templates

1 reference

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Evidence that Smad2 is a tumor suppressor implicated in the control of cellular invasion

1 reference

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Smad2 role in mesoderm formation, left-right patterning and craniofacial development

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The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

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29 September 2017

Activation of signalling by the activin receptor complex

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A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

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A genetic model for colorectal tumorigenesis

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Down-regulation of activin, activin receptors, and Smads in high-grade breast cancer.

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4 September 2018

Wnt signaling controls the phosphorylation status of beta-catenin.

1 reference

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Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.

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Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

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4 September 2018

Cross-talk between the TGFbeta and Wnt signaling pathways in murine embryonic maxillary mesenchymal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18595660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18595660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic in vivo alterations of the JV18-1 gene at 18q21 in human lung cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18595660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Smad proteins in human colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18595660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CELLSIG.2008.05.003

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18595660%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18595660%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18595660%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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