(Q36963125)

17 August 2017

1 reference

title

Engineering secretable forms of chaperones for immune modulation and vaccine development (English)

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17 August 2017

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Beachy SH

1

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17 August 2017

Kisailus AJ

2

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17 August 2017

Repasky EA

3

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17 August 2017

Subjeck JR

4

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17 August 2017

Wang XY

5

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17 August 2017

Kazim AL

6

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17 August 2017

publication date

1 November 2007

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17 August 2017

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17 August 2017

volume

43

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17 August 2017

issue

3

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17 August 2017

page(s)

184-193

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17 August 2017

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Inconstant association between 27-kDa heat-shock protein (Hsp27) content and doxorubicin resistance in human colon cancer cells. The doxorubicin-protecting effect of Hsp27

7 January 2021

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Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1- and staurosporine-induced cell death.

7 January 2021

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Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma

7 January 2021

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The 70 kilodalton heat shock protein is an inhibitor of apoptosis in prostate cancer.

7 January 2021

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Heat shock proteins in cancer: chaperones of tumorigenesis

7 January 2021

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The nucleation and maintenance of heterochromatin by a histone deacetylase in fission yeast.

7 January 2021

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GRP94, an ER chaperone with protein and peptide binding properties

7 January 2021

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Identification of novel peptide binding proteins in the endoplasmic reticulum: ERp72, calnexin, and grp170.

7 January 2021

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The 170-kDa glucose-regulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin

7 January 2021

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Tumor-specific cell surface expression of the -KDEL containing endoplasmic reticular heat shock protein gp96

7 January 2021

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7 January 2021

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7 January 2021

based on heuristic

Forced expression of heat-shock protein 70 increases the secretion of Hsp70 and provides protection against tumour growth

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat shock protein 70 is secreted from tumor cells by a nonclassical pathway involving lysosomal endosomes

7 January 2021

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Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cells

7 January 2021

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The release of Hsp70 from A431 carcinoma cells is mediated by secretory-like granules

7 January 2021

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Effects of exogenous stress protein 70 on the functional properties of human promonocytes through binding to cell surface and internalization

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Extracellular heat shock protein 70: a critical component for motoneuron survival

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

The acute phase protein haptoglobin is a mammalian extracellular chaperone with an action similar to clusterin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Quality control of protein folding in extracellular space

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

The danger model: a renewed sense of self

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Danger signals: SOS to the immune system

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Tumor rejection antigens of chemically induced sarcomas of inbred mice

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat shock protein 70-associated peptides elicit specific cancer immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Re-evaluating the role of heat-shock protein-peptide interactions in tumour immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Binding of the viral immunogenic octapeptide VSV8 to native glucose-regulated protein Grp94 (gp96) and its inhibition by the physiological ligands ATP and Ca2+.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Immunotherapy for human cancer using heat shock protein-peptide complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

The role of heat shock protein (hsp70) in dendritic cell maturation: hsp70 induces the maturation of immature dendritic cells but reduces DC differentiation from monocyte precursors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

A proposed mechanism for the induction of cytotoxic T lymphocyte production by heat shock fusion proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat shock proteins gp96 and hsp70 activate the release of nitric oxide by APCs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Cross-presentation of glycoprotein 96-associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

How is the immune response affected by hyperthermia and heat shock proteins?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat shock protein 70-reactivity is associated with increased cell surface density of CD94/CD56 on primary natural killer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Effects of thermal stress on tumor antigenicity and recognition by immune effector cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

The cell surface-localized heat shock protein 70 epitope TKD induces migration and cytolytic activity selectively in human NK cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Role of scavenger receptors in the binding and internalization of heat shock protein 70.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Scavenger receptor-A mediates gp96/GRP94 and calreticulin internalization by antigen-presenting cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

CD91: a receptor for heat shock protein gp96

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Extracellular HSP70 binding to surface receptors present on antigen presenting cells and endothelial/epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat shock proteins and scavenger receptors: role in adaptive immune responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Roles of heat-shock proteins in innate and adaptive immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Characterization of heat shock protein 110 and glucose-regulated protein 170 as cancer vaccines and the effect of fever-range hyperthermia on vaccine activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Effect of adenovirus-mediated heat shock protein expression and oncolysis in combination with low-dose cyclophosphamide treatment on antitumor immune responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat shock protein-peptide complexes, reconstituted in vitro, elicit peptide-specific cytotoxic T lymphocyte response and tumor immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

The chaperoning properties of mouse grp170, a member of the third family of hsp70 related proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

HSP110-HER2/neu Chaperone Complex Vaccine Induces Protective Immunity Against Spontaneous Mammary Tumors in HER-2/neu Transgenic Mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Chaperoning function of stress protein grp170, a member of the hsp70 superfamily, is responsible for its immunoadjuvant activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat shock fusion proteins as vehicles for antigen delivery into the major histocompatibility complex class I presentation pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Tumor-derived, chaperone-rich cell lysate activates dendritic cells and elicits potent antitumor immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Proteomics shows Hsp70 does not bind peptide sequences indiscriminately in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Surface expression of Hsp25 and Hsp72 differentially regulates tumor growth and metastasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

A stress-inducible 72-kDa heat-shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat shock protein 70 and glycoprotein 96 are differentially expressed on the surface of malignant and nonmalignant breast cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Effects of antineoplastic agents on cytoplasmic and membrane-bound heat shock protein 70 (Hsp70) levels.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Hyperthermia enhances CTL cross-priming

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Dual function of membrane-bound heat shock protein 70 (Hsp70), Bag-4, and Hsp40: protection against radiation-induced effects and target structure for natural killer cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Differential up-regulation of cytosolic and membrane-bound heat shock protein 70 in tumor cells by anti-inflammatory drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Alternative mechanism by which IFN-gamma enhances tumor recognition: active release of heat shock protein 72.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Phospholipse c inhibitor, u73122, stimulates release of hsp-70 stress protein from A431 human carcinoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Complex formation of 70-kDa heat shock protein with acidic glycolipids and phospholipids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Exosomes from plasmacytoma cells as a tumor vaccine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Releasing signals, secretory pathways, and immune function of endogenous extracellular heat shock protein 72.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Silencing the hsp25 gene eliminates migration capability of the highly metastatic murine 4T1 breast adenocarcinoma cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Natural adjuvants: endogenous activators of dendritic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

A simple method to cure established tumors by inflammatory killing of normal cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Potent tumor-specific immunity induced by an in vivo heat shock protein-suicide gene-based tumor vaccine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat induced release of Hsp70 from prostate carcinoma cells involves both active secretion and passive release from necrotic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Enhancement of Cancer Radiation Therapy by Use of Adenovirus-Mediated Secretable Glucose-Regulated Protein 94/gp96 Expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat shock fusion protein gp96-Ig mediates strong CD8 CTL expansion in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Glucose-regulated protein 94/glycoprotein 96 elicits bystander activation of CD4+ T cell Th1 cytokine production in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Cell surface targeting of heat shock protein gp96 induces dendritic cell maturation and antitumor immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Extracellular targeting of endoplasmic reticulum chaperone glucose-regulated protein 170 enhances tumor immunity to a poorly immunogenic melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Enhanced efficacy of tumor cell vaccines transfected with secretable hsp70.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

A novel anticancer approach: SEA-anchored tumor cells expressing heat shock protein 70 onto the surface elicit strong anticancer efficacy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Tumor cell membrane-bound heat shock protein 70 elicits antitumor immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Calreticulin exposure dictates the immunogenicity of cancer cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Intracellular signaling by the unfolded protein response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Quality control in the endoplasmic reticulum protein factory

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Unfolded protein response in a Drosophila model for retinal degeneration

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Perforin is required for innate and adaptive immunity induced by heat shock protein gp96.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

The dual nature of specific immunological activity of tumor-derived gp96 preparations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Over-expression of hsp70 confers tumorigenicity to mouse fibrosarcoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Expression of stress response protein glucose regulated protein-78 mediated by c-Myb

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

The regulation of exosome secretion: a novel function of the p53 protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Exosome release is regulated by a calcium-dependent mechanism in K562 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

A cure for traffic jams: small molecule chaperones in the endoplasmic reticulum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

Virally induced lytic cell death elicits the release of immunogenic GRP94/gp96

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

GRP94 (gp96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.06.001

10.1016/J.YMETH.2007.06.001

7 January 2021

Identifiers

DOI

1 reference

17 August 2017

1 reference