(Q36963811)

17 August 2017

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title

Apoptosis regulators as targets for cancer therapy (English)

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17 August 2017

Fernández-Luna JL

1

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17 August 2017

1 September 2007

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Clinical and Translational Oncology

17 August 2017

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17 August 2017

9

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17 August 2017

555-562

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17 August 2017

9

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https://scigraph.springernature.com/pub.10.1007/s12094-007-0103-7

17 August 2017

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cites work

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12094-007-0103-7

Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12094-007-0103-7

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

21 January 2018

1 reference

12 December 2020

Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins

1 reference

12 December 2020

Why neurons die: cell death in the nervous system.

1 reference

12 December 2020

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

1 reference

12 December 2020

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

12 December 2020

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

12 December 2020

Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas

1 reference

12 December 2020

Oncogenic potential of bcl-2 demonstrated by gene transfer.

1 reference

12 December 2020

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors

1 reference

12 December 2020

Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand receptor-1.

1 reference

12 December 2020

Proapoptotic BID is required for myeloid homeostasis and tumor suppression

1 reference

12 December 2020

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors

1 reference

12 December 2020

Breast cancer cells can evade apoptosis-mediated selective killing by a novel small molecule inhibitor of Bcl-2

1 reference

12 December 2020

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

1 reference

12 December 2020

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

1 reference

12 December 2020

Bad-deficient mice develop diffuse large B cell lymphoma

1 reference

12 December 2020

A unified model for apical caspase activation

1 reference

12 December 2020

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

1 reference

12 December 2020

Cell death in the nervous system

1 reference

12 December 2020

Drug insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms

1 reference

12 December 2020

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

1 reference

12 December 2020

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death

1 reference

12 December 2020

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

12 December 2020

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

1 reference

12 December 2020

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

1 reference

12 December 2020

Caspases: the proteases of the apoptotic pathway

1 reference

12 December 2020

Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy

1 reference

12 December 2020

The apoptosome activates caspase-9 by dimerization

1 reference

12 December 2020

Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death

1 reference

12 December 2020

Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay

1 reference

12 December 2020

Apoptosis in development

1 reference

12 December 2020

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

12 December 2020

The ins and outs of programmed cell death during C. elegans development

1 reference

12 December 2020

harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)

1 reference

12 December 2020

IAPs, RINGs and ubiquitylation

1 reference

12 December 2020

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

12 December 2020

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

1 reference

12 December 2020

TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice

1 reference

12 December 2020

BID: a novel BH3 domain-only death agonist

1 reference

12 December 2020

An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12

1 reference

12 December 2020

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

1 reference

12 December 2020

Critical role for DP5/Harakiri, a Bcl-2 homology domain 3-only Bcl-2 family member, in axotomy-induced neuronal cell death.

1 reference

12 December 2020

Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM.

1 reference

12 December 2020

Morphologic and biochemical hallmarks of apoptosis

1 reference

12 December 2020

Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway

1 reference

12 December 2020

Oblimersen Bcl-2 antisense: facilitating apoptosis in anticancer treatment

1 reference

12 December 2020

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

1 reference

12 December 2020

Apoptosis in human disease: a new skin for the old ceremony?

1 reference

12 December 2020

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

1 reference

12 December 2020

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

1 reference

12 December 2020

BH3-only proteins in control: specificity regulates MCL-1 and BAK-mediated apoptosis

1 reference

12 December 2020

Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells

1 reference

12 December 2020

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

1 reference

12 December 2020

10.1007/S12094-007-0103-7

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

17921102