(Q36968413)

English

The kinase activity of IL-1 receptor-associated kinase 4 is required for interleukin-1 receptor/toll-like receptor-induced TAK1-dependent NFkappaB activation

scientific article published on 15 September 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

The kinase activity of IL-1 receptor-associated kinase 4 is required for interleukin-1 receptor/toll-like receptor-induced TAK1-dependent NFkappaB activation (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

toll-like receptor

0 references

Jean-Laurent Casanova

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

4

object named as

Jianhong Yao

1 reference

Europe PubMed Central

17 August 2017

PMC publication ID

1

object named as

Jerzy Fraczek

1 reference

Europe PubMed Central

17 August 2017

PMC publication ID

author name string

Tae Whan Kim

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Hui Xiao

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Qian Wen

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Yali Li

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Juliusz Pryjma

8

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Xiaoxia Li

9

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

15 September 2008

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

283

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

46

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

31697-31705

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

IRAK-4 kinase activity is required for interleukin-1 (IL-1) receptor- and toll-like receptor 7-mediated signaling and gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

Cutting edge: molecular structure of the IL-1R-associated kinase-4 death domain and its implications for TLR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

A toll-like receptor that prevents infection by uropathogenic bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

Pyogenic bacterial infections in humans with IRAK-4 deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

Toll-like receptors: critical proteins linking innate and acquired immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

A Toll-like receptor recognizes bacterial DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

TLR6: A novel member of an expanding toll-like receptor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

A family of human receptors structurally related to Drosophila Toll

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

TRAF6 is a signal transducer for interleukin-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

IRAK: a kinase associated with the interleukin-1 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

29 September 2017

IRAK-4 kinase activity-dependent and -independent regulation of lipopolysaccharide-inducible genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

4 September 2018

Regulation of human IP-10 gene expression in astrocytoma cells by inflammatory cytokines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

4 September 2018

Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581573

20 October 2018

IRAK4 in TLR/IL-1R signaling: possible clinical applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/18794297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification

1 reference

https://pubmed.ncbi.nlm.nih.gov/18794297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M804779200

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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