(Q36970205)

17 August 2017

1 reference

title

Erythroid and megakaryocytic transformation (English)

1 reference

17 August 2017

A Wickrema

1

1 reference

PubMed ID

17934487

17 August 2017

J D Crispino

series ordinal

2

1 reference

PubMed ID

17934487

17 August 2017

language of work or name

English

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publication date

1 October 2007

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17 August 2017

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17 August 2017

26

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17 August 2017

47

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17 August 2017

6803-6815

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210763

17 August 2017

0 references

cites work

High incidence of CALM-AF10 fusion and the identification of a novel fusion transcript in acute megakaryoblastic leukemia in children without Down's syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

The NF-E2 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Transcriptional regulation of erythropoiesis: an affair involving multiple partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

split ends, a new component of the Drosophila EGF receptor pathway, regulates development of midline glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Transmembrane domain of the envelope gene of a polycythemia-inducing retrovirus determines erythropoietin-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

GATA1 in normal and malignant hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Malignant hematopoietic cell lines: in vitro models for the study of erythroleukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Growth factor-independent 1B gene (GFI1B) is overexpressed in erythropoietic and megakaryocytic malignancies and increases their proliferation rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Role of the transmembrane sequence of spleen focus-forming virus gp55 in erythroleukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Cell-free transmission in adult Swiss mice of a disease having the character of a leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Genetics of myeloid malignancies: pathogenetic and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Acute myeloid leukemia and Down syndrome evolution of modern therapy--state of the art review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Gfi-1B plays a critical role in terminal differentiation of normal and transformed erythroid progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Gene expression profiling in polycythaemia vera: overexpression of transcription factor NF-E2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Perspective: chromosomal aneuploidy in leukemia--lessons from down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Tumor necrosis factor-alpha expressed constitutively in erythroid cells or induced by erythropoietin has negative and stimulatory roles in normal erythropoiesis and erythroleukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Transcriptional regulation of megakaryopoiesis: thrombopoietin signaling and nuclear factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Kit-activating mutations cooperate with Spi-1/PU.1 overexpression to promote tumorigenic progression during erythroleukemia in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

New insights into erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

A gain-of-function mutation of JAK2 in myeloproliferative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

The management of neoplastic disorders of haematopoiesis in children with Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Increased megakaryocytopoiesis in Lyn-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Identification and activation of Src family kinases in primary megakaryocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Retroviral integration within the Fli-2 locus results in inactivation of the erythroid transcription factor NF-E2 in Friend erythroleukemias: evidence that NF-E2 is essential for globin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Overexpression of Ets-1 in human hematopoietic progenitor cells blocks erythroid and promotes megakaryocytic differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Rbm15 modulates Notch-induced transcriptional activation and affects myeloid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Transcription factor GATA-1 and Down syndrome leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

JAK2 V617F in myeloid disorders: what do we know now, and where are we headed?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Increased dosage of the RUNX1/AML1 gene: a third mode of RUNX leukemia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Maturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Erythroleukemia: a need for a new definition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

The 8;21 translocation in leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Congenital erythropoietic porphyria due to a mutation in GATA1: the first trans-acting mutation causative for a human porphyria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

AML1 deletion in adult mice causes splenomegaly and lymphomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Ott1(Rbm15) has pleiotropic roles in hematopoietic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Megakaryocyte polyploidization is associated with a functional gene amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Roads to polyploidy: the megakaryocyte example

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Avian erythroleukemia: a model for corepressor function in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Transcription factors in myeloid development: balancing differentiation with transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Target cells infected by avian erythroblastosis virus differentiate and become transformed

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

More on Myb in myelofibrosis: molecular analyses of MYB and EP300 in 55 patients with myeloproliferative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Molecular mechanisms of megakaryopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

GRB2-mediated recruitment of GAB2, but not GAB1, to SF-STK supports the expansion of Friend virus-infected erythroid progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

X-linked gray platelet syndrome due to a GATA1 Arg216Gln mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Development of myelofibrosis in mice genetically impaired for GATA-1 expression (GATA-1(low) mice).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Molecular insights into Down syndrome-associated leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Down myeloid disorders: a paradigm for childhood preleukaemia and leukaemia and insights into normal megakaryopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Activating alleles of JAK3 in acute megakaryoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Engagement of Gab1 and Gab2 in erythropoietin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Identification of a TAL1 Target Gene Reveals a Positive Role for the LIM Domain-Binding Protein Ldb1 in Erythroid Gene Expression and Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Haploinsufficiency of Runx1/AML1 promotes myeloid features and leukaemogenesis in BXH2 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Increased dosage of Runx1/AML1 acts as a positive modulator of myeloid leukemogenesis in BXH2 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Identification of an acquired JAK2 mutation in polycythemia vera

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

JAK2 V617F is a rare finding in de novo acute myeloid leukemia, but STAT3 activation is common and remains unexplained

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

Long-term results of an ultra low-dose cytarabine-based regimen for the treatment of acute megakaryoblastic leukaemia in children with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Incidence and treatment of potentially lethal diseases in transient leukemia of Down syndrome: Pediatric Oncology Group Study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Comparison of childhood myelodysplastic syndrome, AML FAB M6 or M7, CCG 2891: report from the Children's Oncology Group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Nineteen cases of the t(1;22)(p13;q13) acute megakaryblastic leukaemia of infants/children and a review of 39 cases: report from a t(1;22) study group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Ets and retroviruses - transduction and activation of members of the Ets oncogene family in viral oncogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Purification, amplification and characterization of a population of human erythroid progenitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

The relationship between human megakaryocyte nuclear DNA content and gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Expression of erythroid-specific genes in acute megakaryoblastic leukaemia and transient myeloproliferative disorder in Down's syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Constitutive activation of Stat1 and Stat3 in primary erythroleukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Splenic erythroblasts in anemia-inducing Friend disease: a source of cells for studies of erythropoietin-mediated differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Adult acute megakaryocytic leukemia: an analysis of 37 patients treated at M.D. Anderson Cancer Center

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Acute megakaryoblastic leukemia: experience of GIMEMA trials

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

The proto-oncogene ERG in megakaryoblastic leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Prognostic factors and outcome of recurrence in childhood acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Histone H5 in the immature blood cells of chickens with leukosis induced by avian leukosis virus strain E26.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Haploinsufficiency of AML1 results in a decrease in the number of LTR-HSCs while simultaneously inducing an increase in more mature progenitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210763

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210763

1 reference

17 August 2017

1 reference

PubMed ID

17934487