(Q36970549)

English

Activation and products of the cryptic secondary metabolite biosynthetic gene clusters by rifampin resistance (rpoB) mutations in actinomycetes

scientific article published on 19 April 2013

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Activation and products of the cryptic secondary metabolite biosynthetic gene clusters by rifampin resistance (rpoB) mutations in actinomycetes (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

1 reference

based on heuristic

inferred from title

secondary metabolite

1 reference

based on heuristic

inferred from title

author name string

Yukinori Tanaka

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Ken Kasahara

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Yutaka Hirose

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Kiriko Murakami

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Rie Kugimiya

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Kozo Ochi

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

19 April 2013

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Journal of Bacteriology

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

195

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

13

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

2959-2970

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Chemical perturbation of secondary metabolism demonstrates important links to primary metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Scandium stimulates the production of amylase and bacilysin in Bacillus subtilis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Strain improvement in actinomycetes in the postgenomic era.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Antibiotic overproduction by rpsL and rsmG mutants of various actinomycetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

The biosynthetic potential of myxobacteria and their impact in drug discovery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Phenotypes and gene expression profiles of Saccharopolyspora erythraea rifampicin-resistant (rif) mutants affected in erythromycin production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Regulation of the Bacillus subtilis divergent yetL and yetM genes by a transcriptional repressor, YetL, in response to flavonoids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Activation of dormant bacterial genes by Nonomuraea sp. strain ATCC 39727 mutant-type RNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

A key developmental regulator controls the synthesis of the antibiotic erythromycin in Saccharopolyspora erythraea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Dramatic activation of antibiotic production in Streptomyces coelicolor by cumulative drug resistance mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

From microbial differentiation to ribosome engineering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Natural products as sources of new drugs over the last 25 years

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

New antibiotics from bacterial natural products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Novel rpoB mutations conferring rifampin resistance on Bacillus subtilis: global effects on growth, competence, sporulation, and germination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Innovative approach for improvement of an antibiotic-overproducing industrial strain of Streptomyces albus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Enhanced expression of S-adenosylmethionine synthetase causes overproduction of actinorhodin in Streptomyces coelicolor A3(2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Activation of antibiotic biosynthesis by specified mutations in the rpoB gene (encoding the RNA polymerase beta subunit) of Streptomyces lividans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

BldD is a direct regulator of key developmental genes in Streptomyces coelicolor A3(2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Novel approach for improving the productivity of antibiotic-producing strains by inducing combined resistant mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Combinatorial approaches to polyketide biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Production of actinorhodin-related "blue pigments" by Streptomyces coelicolor A3(2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Metabolic initiation of differentiation and secondary metabolism by Streptomyces griseus: significance of the stringent response (ppGpp) and GTP content in relation to A factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

29 September 2017

Biosynthesis of formycin. Role of certain amino acids in formycin biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

27 June 2018

Rare earth elements activate the secondary metabolite-biosynthetic gene clusters in Streptomyces coelicolor A3(2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

4 September 2018

The G243D mutation (afsB mutation) in the principal sigma factor sigmaHrdB alters intracellular ppGpp level and antibiotic production in Streptomyces coelicolor A3(2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

4 September 2018

Production improvement of antifungal, antitrypanosomal nucleoside sinefungin by rpoB mutation and optimization of resting cell system of Streptomyces incarnatus NRRL 8089.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

4 September 2018

Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

4 September 2018

Biosynthesis of actinorhodin and related antibiotics: discovery of alternative routes for quinone formation encoded in the act gene cluster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

4 September 2018

Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

4 September 2018

Increased expression of ribosome recycling factor is responsible for the enhanced protein synthesis during the late growth phase in an antibiotic-overproducing Streptomyces coelicolor ribosomal rpsL mutant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

4 September 2018

RNA Polymerase Mutation Activates the Production of a Dormant Antibiotic 3,3′-Neotrehalosadiamine via an Autoinduction Mechanism in Bacillus subtilis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

4 September 2018

Genetic and physiological characterization of rpoB mutations that activate antibiotic production in Streptomyces lividans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

4 September 2018

A rifampicin resistance mutation in the rpoB gene confers ppGpp-independent antibiotic production in Streptomyces coelicolor A3(2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697537

4 September 2018

The regulator of streptomycin gene expression, StrR, of Streptomyces griseus is a DNA binding activator protein with multiple recognition sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/23603745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rare earth, scandium, causes antibiotic overproduction in Streptomyces spp

1 reference

https://pubmed.ncbi.nlm.nih.gov/23603745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of the ability to produce secondary metabolites in Streptomyces through the acquisition of erythromycin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23603745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of secondary metabolite-biosynthetic gene clusters by generating rsmG mutations in Streptomyces griseus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23603745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A magic bullet for antibiotic discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/23603745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stationary-phase production of the antibiotic actinorhodin in Streptomyces coelicolor A3(2) is transcriptionally regulated

1 reference

https://pubmed.ncbi.nlm.nih.gov/23603745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vancomycin production in batch and continuous culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/23603745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JB.00147-13

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36970549&oldid=1762049388"