(Q36679241)

15 August 2017

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title

New antibiotics from bacterial natural products (English)

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15 August 2017

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1

Jon Clardy

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15 August 2017

2

Michael A Fischbach

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15 August 2017

3

Christopher T Walsh

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PubMed ID

17160060

15 August 2017

language of work or name

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1 December 2006

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15 August 2017

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24

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15 August 2017

1541-1550

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12

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https://scigraph.springernature.com/pub.10.1038/nbt1266

15 August 2017

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Novel natural products from soil DNA libraries in a streptomycete host

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Palmitoylputrescine, an antibiotic isolated from the heterologous expression of DNA extracted from bromeliad tank water

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Drug discovery from natural products

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Improving on nature: antibiotics that target the ribosome

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A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

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Structure and mechanism of DNA topoisomerases.

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Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

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Inhibiting bacterial fatty acid synthesis

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Platensimycin is a selective FabF inhibitor with potent antibiotic properties

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Pyrrolidinedione derivatives as antibacterial agents with a novel mode of action

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Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants

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Identification and characterization of the first class of potent bacterial acetyl-CoA carboxylase inhibitors with antibacterial activity.

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7 January 2021

Lipid II as a target for antibiotics

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7 January 2021

Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production

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Glycopeptide and lipoglycopeptide antibiotics

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Chemistry and biology of ramoplanin: a lipoglycodepsipeptide with potent antibiotic activity

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New developments in lantibiotic biosynthesis and mode of action.

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Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis.

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7 January 2021

The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics

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7 January 2021

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7 January 2021

Arylomycins A and B, new biaryl-bridged lipopeptide antibiotics produced by Streptomyces sp. Tü 6075. I. Taxonomy, fermentation, isolation and biological activities.

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7 January 2021

Novel lipoglycopeptides as inhibitors of bacterial signal peptidase I.

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7 January 2021

Crystallographic and biophysical analysis of a bacterial signal peptidase in complex with a lipopeptide-based inhibitor

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7 January 2021

Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway

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7 January 2021

A Diels-Alder macrocyclization enables an efficient asymmetric synthesis of the antibacterial natural product abyssomicin C

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7 January 2021

Lessons from natural molecules

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7 January 2021

Exploring nitrilase sequence space for enantioselective catalysis

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7 January 2021

Identifiers

DOI

10.1038/NBT1266

1 reference

PubMed ID

17160060

Dimensions Publication ID

15 August 2017

0 references

1 reference

PubMed ID

17160060