(Q36994766)

English

The p85alpha subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration

scientific article published on 22 September 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

The p85alpha subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

author name string

Veerendra Munugalavadla

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Sasidhar Vemula

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Emily Catherine Sims

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Subha Krishnan

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Shi Chen

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Jincheng Yan

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Huijie Li

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Paul J Niziolek

8

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Clifford Takemoto

9

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Alexander G Robling

10

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Feng-Chun Yang

11

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Reuben Kapur

12

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Europe PubMed Central

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17 August 2017

language of work or name

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publication date

22 September 2008

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

28

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

23

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

7182-7198

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Possible role of direct Rac1-Rab7 interaction in ruffled border formation of osteoclasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

p85alpha subunit of class IA PI-3 kinase is crucial for macrophage growth and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Preprocessing of oligonucleotide array data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Mitf and Tfe3: members of a b-HLH-ZIP transcription factor family essential for osteoclast development and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

The expanding role of PI3-kinase in bone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Phosphoinositide 3-kinase signalling--which way to target?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Osteoclast differentiation and activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Signal transduction pathways regulating osteoclast differentiation and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Jun Dimerization Protein 2 (JDP2), a Member of the AP-1 Family of Transcription Factor, Mediates Osteoclast Differentiation Induced by RANKL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Synthesis and function of 3-phosphorylated inositol lipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Ras and Rho GTPases: a family reunion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Modulation of cellular apoptotic potential: contributions to oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Rac-GTPase, osteoclast cytoskeleton and bone resorption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Lipopolysaccharide-stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Identification of two SH3-binding motifs in the regulatory subunit of phosphatidylinositol 3-kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3′-kinase SH2 domains: a model for SH2-mediated receptor-target interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

9 September 2017

c-Fms and the alphavbeta3 integrin collaborate during osteoclast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

29 September 2017

PI3-K/AKT regulation of NF-kappaB signaling events in suppression of TNF-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

29 September 2017

Osteopetrosis in mice lacking haematopoietic transcription factor PU.1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

29 September 2017

Role of matrix metalloproteinases in human periodontal diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

29 September 2017

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

27 June 2018

Mice lacking cathepsin K maintain bone remodeling but develop bone fragility despite high bone mass.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

Vav3 regulates osteoclast function and bone mass

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

Osteoclast-derived serum tartrate-resistant acid phosphatase 5b in Albers-Schonberg disease (type II autosomal dominant osteopetrosis).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

High dose M-CSF partially rescues the Dap12-/- osteoclast phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

A novel immunoassay for the determination of tartrate-resistant acid phosphatase 5b from rat serum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

Isolation of human osteoclasts formed in vitro: hormonal effects on the bone-resorbing activity of human osteoclasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

Linkage of M-CSF signaling to Mitf, TFE3, and the osteoclast defect in Mitf(mi/mi) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

The role of phosphoinositide 3-kinase in spreading osteoclasts induced by colony-stimulating factor-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

A role for TGFbeta(1) in osteoclast differentiation and survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

Multiple isoforms of the regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase) are expressed in neurons in the rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

Wortmannin, a specific inhibitor of phosphatidylinositol-3 kinase, blocks osteoclastic bone resorption.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593377

4 September 2018

Role of 1 alpha,25-dihydroxyvitamin D3 in osteoclast differentiation and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18809581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wortmannin inhibits spreading and chemotaxis of rat osteoclasts in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18809581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous production of TGF-beta is essential for osteoclastogenesis induced by a combination of receptor activator of NF-kappa B ligand and macrophage-colony-stimulating factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18809581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid screening method for osteoclast differentiation in vitro that measures tartrate-resistant acid phosphatase 5b activity secreted into the culture medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/18809581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between histomorphometric parameters of bone resorption and serum type 5b tartrate-resistant acid phosphatase in uremic patients on maintenance hemodialysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18809581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic evidence for convergence of c-Kit- and alpha4 integrin-mediated signals on class IA PI-3kinase and the Rac pathway in regulating integrin-directed migration in mast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18809581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusion disability of embryonic osteoclast precursor cells and macrophages in the microphthalmic osteopetrotic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/18809581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/18809581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00920-08

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

0 references

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