(Q36998857)

17 August 2017

1 reference

title

Voltage-gated sodium channel blockers for the treatment of neuropathic pain (English)

1 reference

17 August 2017

0 references

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Theodore R Cummins

1

1 reference

17 August 2017

Anthony M Rush

series ordinal

2

1 reference

17 August 2017

language of work or name

1 reference

1 November 2007

1 reference

Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

17 August 2017

published in

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17 August 2017

volume

7

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17 August 2017

issue

11

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17 August 2017

page(s)

1597-1612

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Defining neuropathic pain

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A treatment algorithm for neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Cell type-specific changes of the membrane properties of peripherally-axotomized dorsal root ganglion neurons in a rat model of neuropathic pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Change in excitability and phenotype of substance P and its receptor in cat Abeta sensory neurons following peripheral inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Systemic lidocaine for neuropathic pain relief

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Continuous lidocaine infusion for the relief of refractory malignant pain in a terminally ill pediatric cancer patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Resurgence of sodium channel research

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

The role of sodium channels in chronic inflammatory and neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Inherited disorders of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Transcriptional channelopathies: an emerging class of disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Sodium channel beta subunits: anything but auxiliary

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Nomenclature of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Structure and distribution of a broadly expressed atypical sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Nax channel involved in CNS sodium-level sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Sodium channel alpha-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): different expression patterns in developing rat nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Localization of voltage-gated ion channels in mammalian brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Na(v)1.5 underlies the 'third TTX-R sodium current' in rat small DRG neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Diversity of expression of the sensory neuron-specific TTX-resistant voltage-gated sodium ion channels SNS and SNS2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Potent analgesic effects of GDNF in neuropathic pain states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Molecular mechanisms of neurotoxin action on voltage-gated sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Differences in saxitoxin and tetrodotoxin binding revealed by mutagenesis of the Na+ channel outer vestibule.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A single serine residue confers tetrodotoxin insensitivity on the rat sensory-neuron-specific sodium channel SNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Critical molecular determinants of voltage-gated sodium channel sensitivity to mu-conotoxins GIIIA/B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Molecular basis of isoform-specific micro-conotoxin block of cardiac, skeletal muscle, and brain Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

An evaluation of intrathecal ziconotide for the treatment of chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

muO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Synthetic muO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1.8 and has a long-lasting analgesic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Voltage-gated sodium channel toxins: poisons, probes, and future promise

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

An overview of peptide toxins from the venom of the Chinese bird spider Selenocosmia huwena Wang [=Ornithoctonus huwena (Wang)].

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Two tarantula peptides inhibit activation of multiple sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Voltage-gated sodium channels as therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na(+) channel alpha subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel alpha subunit in voltage-dependent gating and drug block.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Interactions of local anesthetics with voltage-gated Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Relationship between the firing frequency of injured peripheral neurons and inhibition of firing by sodium channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Lacosamide: a review of preclinical properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Molecular basis for exaggerated sensitivity to mexiletine in the cardiac isoform of the fast Na channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Use-dependent block by lidocaine but not amitriptyline is more pronounced in tetrodotoxin (TTX)-Resistant Nav1.8 than in TTX-sensitive Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Phenytoin and carbamazepine: differential inhibition of sodium currents in small cells from adult rat dorsal root ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

The role of voltage-gated sodium channels in neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Voltage-gated sodium channels and hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Systemic lidocaine silences ectopic neuroma and DRG discharge without blocking nerve conduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Autosomal dominant erythermalgia associated with a novel mutation in the voltage-gated sodium channel alpha subunit Nav1.7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Sporadic onset of erythermalgia: a gain-of-function mutation in Nav1.7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Na(V)1.7 mutant A863P in erythromelalgia: effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Characterization of a familial case with primary erythromelalgia from Taiwan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

An SCN9A channelopathy causes congenital inability to experience pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A stop codon mutation in SCN9A causes lack of pain sensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Electrophysiological properties of sodium current subtypes in small cells from adult rat dorsal root ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Two sodium channels contribute to the TTX-R sodium current in primary sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Contribution of the tetrodotoxin-resistant voltage-gated sodium channel NaV1.9 to sensory transmission and nociceptive behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

NaN/Nav1.9: a sodium channel with unique properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

PGE2 increases the tetrodotoxin-resistant Nav1.9 sodium current in mouse DRG neurons via G-proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Tetrodotoxin-resistant Na+ currents and inflammatory hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Small interfering RNA-mediated selective knockdown of Na(V)1.8 tetrodotoxin-resistant sodium channel reverses mechanical allodynia in neuropathic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A tetrodotoxin-resistant sodium current mediates inflammatory pain in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Involvement of the TTX-resistant sodium channel Nav 1.8 in inflammatory and neuropathic, but not post-operative, pain states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Ceramide, a putative second messenger for nerve growth factor, modulates the TTX-resistant Na(+) current and delayed rectifier K(+) current in rat sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Sphingosine-1-phosphate via activation of a G-protein-coupled receptor(s) enhances the excitability of rat sensory neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A role for the TTX-resistant sodium channel Nav 1.8 in NGF-induced hyperalgesia, but not neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Mechanism of local anesthetic drug action on voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Tetrodotoxin-resistant action potentials in dorsal root ganglion neurons are blocked by local anesthetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Effect of drugs used for neuropathic pain management on tetrodotoxin-resistant Na(+) currents in rat sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Micromolar lidocaine selectively blocks propagating ectopic impulses at a distance from their site of origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

The effect of intravenous lidocaine, tocainide, and mexiletine on spontaneously active fibers originating in rat sciatic neuromas

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Continual systemic infusion of lidocaine provides analgesia in an animal model of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Efficacy of lidocaine patch 5% in the treatment of focal peripheral neuropathic pain syndromes: a randomized, double-blind, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Effectiveness, tolerability, and impact on quality of life of the 5% lidocaine patch in diabetic polyneuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

An open-label study of the lidocaine patch 5% in painful idiopathic sensory polyneuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

The lidocaine patch 5% effectively treats all neuropathic pain qualities: results of a randomized, double-blind, vehicle-controlled, 3-week efficacy study with use of the neuropathic pain scale.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Use of lidocaine patch 5% for chronic low back pain: a report of four cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Safety and tolerability of the lidocaine patch 5%, a targeted peripheral analgesic: a review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A randomized, double-masked, placebo-controlled pilot trial of extended IV lidocaine infusion for relief of ongoing neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Lidocaine block of cardiac sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Differential effect of ketamine and lidocaine on spontaneous and mechanical evoked pain in patients with nerve injury pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Local anesthetic effects on priming and activation of human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Inhibition of m3 muscarinic acetylcholine receptors by local anaesthetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Inhibition of mammalian Gq protein function by local anesthetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Lidocaine enhances Galphai protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Time-dependent inhibition of G protein-coupled receptor signaling by local anesthetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

The cutaneous analgesic effect of class I antiarrhythmic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A comparison of the antinociceptive effects of voltage-activated Na+ channel blockers in two rat models of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Critical review of oral drug treatments for diabetic neuropathic pain-clinical outcomes based on efficacy and safety data from placebo-controlled and direct comparative studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Antiepileptic drugs in the treatment of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Carbamazepine interacts with a slow inactivation state of NaV1.8-like sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

The suppressive effects of oxcarbazepine on mechanical and cold allodynia in a rat model of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Oxcarbazepine is effective and safe in the treatment of neuropathic pain: pooled analysis of seven clinical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Oxcarbazepine for treating paroxysmal painful symptoms in multiple sclerosis: a pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Oxcarbazepine in painful diabetic neuropathy: results of a dose-ranging study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Oxcarbazepine in painful diabetic neuropathy: a randomized, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Lamotrigine for treatment of pain associated with diabetic neuropathy: results of two randomized, double-blind, placebo-controlled studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Zonisamide in the treatment of painful diabetic neuropathy: a randomized, double-blind, placebo-controlled pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A comparative study of the action of tolperisone on seven different voltage dependent sodium channel isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Amitriptyline versus placebo in postherpetic neuralgia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Antidepressants in the treatment of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Intrathecal tri-cyclic antidepressants produce spinal anesthesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Amitriptyline modulation of Na(+) channels in rat dorsal root ganglion neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

State-dependent block of voltage-gated Na+ channels by amitriptyline via the local anesthetic receptor and its implication for neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Sodium channel blockade may contribute to the analgesic efficacy of antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Inhibition of Nav1.7 and Nav1.4 sodium channels by trifluoperazine involves the local anesthetic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Involvement of calmodulin inhibition in analgesia induced with low doses of intrathecal trifluoperazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of mammalian voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Pharmacology of 2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide: a potent, broad-spectrum state-dependent sodium channel blocker for treating pain states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Reversal of neuropathic pain by alpha-hydroxyphenylamide: a novel sodium channel antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Hydroxyamide analogs of propofol exhibit state-dependent block of sodium channels in hippocampal neurons: implications for anticonvulsant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

The anti-nociceptive agent ralfinamide inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive Na+ currents in dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

21 January 2018

Sodium channel blockers

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Lacosamide, a new anti-epileptic, alleviates neuropathic pain-like behaviors in rat models of spinal cord or trigeminal nerve injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Seeking a mechanism of action for the novel anticonvulsant lacosamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Lacosamide in painful diabetic peripheral neuropathy: a phase 2 double-blind placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Tetrodotoxin inhibits neuropathic ectopic activity in neuromas, dorsal root ganglia and dorsal horn neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Antinociceptive effects of tetrodotoxin (TTX) in rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Neosaxitoxin as a local anesthetic: preliminary observations from a first human trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

A re-examination of tetrodotoxin for prolonged duration local anesthesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na(v1.6) voltage-dependent sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Decrease in inflammatory hyperalgesia by herpes vector-mediated knockdown of Nav1.7 sodium channels in primary afferents

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Short hairpin RNA-mediated selective knockdown of NaV1.8 tetrodotoxin-resistant voltage-gated sodium channel in dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

beta3, a novel auxiliary subunit for the voltage-gated sodium channel, is expressed preferentially in sensory neurons and is upregulated in the chronic constriction injury model of neuropathic pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

Early painful diabetic neuropathy is associated with differential changes in tetrodotoxin-sensitive and -resistant sodium channels in dorsal root ganglion neurons in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.11.1597

10.1586/14737175.7.11.1597

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference