(Q37000231)

English

A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats.

scientific article published on 22 January 2013

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scholarly article

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22 February 2020

A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats (English)

1 reference

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22 February 2020

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Maria Domenica Cappellini

7

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22 February 2020

8

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22 February 2020

author name string

Chia Chi Sun

1

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22 February 2020

Valentina Vaja

2

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22 February 2020

Shanzhuo Chen

3

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22 February 2020

Igor Theurl

4

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22 February 2020

Aaron Stepanek

5

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22 February 2020

Diane E Brown

6

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22 February 2020

Charles C Hong

9

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22 February 2020

Herbert Y Lin

10

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22 February 2020

Jodie L Babitt

11

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22 February 2020

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publication date

22 January 2013

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22 February 2020

Nephrology Dialysis Transplantation

1 reference

Europe PubMed Central

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22 February 2020

28

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22 February 2020

7

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Europe PubMed Central

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22 February 2020

1733-1743

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22 February 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3707526/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Pathways for the regulation of hepcidin expression in anemia of chronic disease and iron deficiency anemia in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Iron supplementation to treat anemia in patients with chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Molecular mechanisms of hepcidin regulation: implications for the anemia of CKD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Hepcidin--a potential novel biomarker for iron status in chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

The role of hepcidin in iron homeostasis and anemia in hemodialysis patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Secondary analysis of the CHOIR trial epoetin-alpha dose and achieved hemoglobin outcomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Fine tuning of hepcidin expression by positive and negative regulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Ferric gluconate reduces epoetin requirements in hemodialysis patients with elevated ferritin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Anemia of chronic disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

A randomized controlled study of iron supplementation in patients treated with erythropoietin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Reduction in recombinant human erythropoietin doses by the use of chronic intravenous iron supplementation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Anemia lessens and its prevention with recombinant human erythropoietin worsens glomerular injury and hypertension in rats with reduced renal mass

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Iron deficiency in patients with dialysis-associated anemia during erythropoietin replacement therapy: strategies for assessment and management.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

29 September 2017

Iron balance in hemodialysis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

27 June 2018

A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

4 September 2018

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

4 September 2018

Alteration of mRNA expression of molecules related to iron metabolism in adenine-induced renal failure rats: a possible mechanism of iron deficiency in chronic kidney disease patients on treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

4 September 2018

Effects of erythropoietin-gene electrotransfer in rats with adenine-induced renal failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

4 September 2018

Evaluation of the erythroid regenerative response in two different models of experimentally induced iron deficiency anemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

4 September 2018

Reduction in erythropoietin doses by the use of chronic intravenous iron supplementation in iron-replete hemodialysis patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

4 September 2018

Effectiveness of intravenous administration of Fe-gluconate-Na complex to maintain adequate body iron stores in hemodialysis patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

4 September 2018

Hematologic and erythropoietin responses to iron dextran in the hemodialysis environment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

4 September 2018

Immunoreactive erythropoietin in serum. I. Evidence for the validity of the assay method and the physiological relevance of estimates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

4 September 2018

Immunoassay for human serum hepcidin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3707526

20 October 2018

Erythropoietic Response and Outcomes in Kidney Disease and Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1093%2FNDT%2FGFS584

21 January 2018

Intravenous iron: how much is too much?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of iron supply for erythropoietin therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of parenteral iron regimens in hemodialysis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous iron supplementation for the treatment of anaemia in pre-dialyzed chronic renal failure patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Q: Is iron therapy for anemia harmful in the setting of infection?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correction of anemia with epoetin alfa in chronic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting higher ferritin concentrations with intravenous iron dextran lowers erythropoietin requirement in hemodialysis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ferric gluconate is highly efficacious in anemic hemodialysis patients with high serum ferritin and low transferrin saturation: results of the Dialysis Patients' Response to IV Iron with Elevated Ferritin (DRIVE) Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An evaluation of the effectiveness of oral iron therapy in hemodialysis patients receiving recombinant human erythropoietin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of purified recombinant human erythropoietin on anemia in rats with experimental renal failure induced by five-sixth nephrectomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythropoietin deficiency and inhibition of erythropoiesis in renal insufficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal model of adenine-induced chronic renal failure in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radioimmunoassay of erythropoietin: circulating levels in normal and polycythemic human beings.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous iron supplementation for the treatment of the anemia of moderate to severe chronic renal failure patients not receiving dialysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NDT/GFS584

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23345622%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23345622%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23345622%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

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