(Q39990819)

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A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells

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scholarly article

1 reference

Europe PubMed Central

16 September 2017

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells (English)

1 reference

Europe PubMed Central

16 September 2017

1 reference

based on heuristic

inferred from title

Matthias Hentze

3

1 reference

Europe PubMed Central

16 September 2017

Guillem Casanovas

object named as

Guillem Casanovas

2

0 references

Martina U Muckenthaler

4

object named as

Martina U Muckenthaler

1 reference

Europe PubMed Central

16 September 2017

author name string

Maria Vittoria Verga Falzacappa

1

1 reference

Europe PubMed Central

16 September 2017

publication date

18 April 2008

1 reference

Europe PubMed Central

16 September 2017

Journal of Molecular Medicine

1 reference

Europe PubMed Central

16 September 2017

86

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Europe PubMed Central

16 September 2017

5

1 reference

Europe PubMed Central

16 September 2017

531-540

1 reference

Europe PubMed Central

16 September 2017

https://scigraph.springernature.com/pub.10.1007/s00109-008-0313-7

0 references

Characterization of a bone morphogenetic protein-responsive Smad-binding element

1 reference

https://api.crossref.org/works/10.1007%2FS00109-008-0313-7

21 January 2018

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepcidin is decreased in TFR2 hemochromatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectrum of hemojuvelin gene mutations in 1q-linked juvenile hemochromatosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Smad transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hierarchical model of gene regulation by transforming growth factor beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 induces hepcidin expression through STAT3

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased hepcidin expression and hypoferraemia associated with an acute phase response are not affected by inactivation of HFE

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distal location of the iron responsive region of the hepcidin promoter.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an element within the promoter of human selenoprotein P responsive to transforming growth factor-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Balancing acts: molecular control of mammalian iron metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mouse model of juvenile hemochromatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of STAT, AP-1, E-box and TIEG motifs in the regulation of hepcidin by IL-6 and BMP-9: lessons from human HAMP and murine Hamp1 and Hamp2 gene promoters

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron imports. IV. Hepcidin and regulation of body iron metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

1 reference

https://pubmed.ncbi.nlm.nih.gov/18421430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00109-008-0313-7

1 reference

Europe PubMed Central

16 September 2017

1 reference

Europe PubMed Central

16 September 2017

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