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Balancing acts: molecular control of mammalian iron metabolism
scientific article (publication date: 30 April 2004)
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review article
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Europe PubMed Central
title
Balancing acts: molecular control of mammalian iron metabolism
(English)
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PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15109490
retrieved
30 April 2017
main subject
iron
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author
Nancy Andrews
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ORCID Public Data File 2021
author name string
Hentze MW
series ordinal
1
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PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15109490
retrieved
30 April 2017
Muckenthaler MU
series ordinal
2
1 reference
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PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15109490
retrieved
30 April 2017
Andrews NC
series ordinal
3
1 reference
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15109490
retrieved
30 April 2017
language of work or name
English
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30 April 2017
publication date
30 April 2004
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30 April 2017
published in
Cell
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15109490
retrieved
30 April 2017
volume
117
1 reference
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15109490
retrieved
30 April 2017
page(s)
285-97
1 reference
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PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15109490
retrieved
30 April 2017
issue
3
1 reference
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PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15109490
retrieved
30 April 2017
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Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: evidence that Yfh1p affects Fe-S cluster synthesis
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Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
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Novel Roles for Iron Regulatory Proteins in the Adaptive Response to Iron Deficiency
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A phosphomimetic mutation at Ser-138 renders iron regulatory protein 1 sensitive to iron-dependent degradation
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Waiting for frataxin
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Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.
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Co-trafficking of HFE, a nonclassical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation.
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A model for the structure and functions of iron-responsive elements
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Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function
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Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system
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Iron regulatory protein 2 as iron sensor. Iron-dependent oxidative modification of cysteine
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A mutation, in the iron-responsive element of H ferritin mRNA, causing autosomal dominant iron overload
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Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family
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Identification of the haemoglobin scavenger receptor.
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Effect of hepcidin on intestinal iron absorption in mice.
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Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
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Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor
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7 January 2021
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A human mitochondrial ferritin encoded by an intronless gene
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7 January 2021
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Transferrin receptor is necessary for development of erythrocytes and the nervous system
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Role of the ferroportin iron-responsive element in iron and nitric oxide dependent gene regulation
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Cytokine-mediated regulation of iron transport in human monocytic cells
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7 January 2021
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1 reference
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reference URL
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7 January 2021
based on heuristic
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An iron-regulated ferric reductase associated with the absorption of dietary iron
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
1 reference
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https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
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Increased lipid peroxidation and mitochondrial dysfunction in aceruloplasminemia brains
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Autosomal-dominant hemochrom-atosis is associated with a mutation in the ferroportin (SLC11A3) gene
1 reference
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https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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based on heuristic
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IRP-1 Binding to Ferritin mRNA Prevents the Recruitment of the Small Ribosomal Subunit by the Cap-Binding Complex eIF4F
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis
1 reference
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https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of ceruloplasmin in cellular iron uptake
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of transient receptor potential canonical 6 (TRPC6) in non-transferrin-bound iron uptake in neuronal phenotype PC12 cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Iron metabolism and mitochondrial abnormalities in Friedreich ataxia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of iron regulatory protein-1 by oxidative stress in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ribosomal pausing and scanning arrest as mechanisms of translational regulation from cap-distal iron-responsive elements
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
A mouse model of familial porphyria cutanea tarda
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship between erythropoiesis and the enhanced intestinal uptake of ferric iron in hypoxia in the mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of ABC7 in the biosynthesis of heme in erythroid cells: interaction of ABC7 with ferrochelatase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of ferritin genes and protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular defect in hypotransferrinemic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An iron delivery pathway mediated by a lipocalin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of reticuloendothelial iron transporter MTP1 (Slc11a3) by inflammation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900343-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(04)00343-5
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
546586
OpenCitations bibliographic resource ID
546586
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
546586
PubMed ID
15109490
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15109490
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
546586
ResearchGate publication ID
271558534
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