(Q37008467)

English

Darbepoetin alfa exerts a cardioprotective effect in autoimmune cardiomyopathy via reduction of ER stress and activation of the PI3K/Akt and STAT3 pathways

scientific article published on 27 May 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Darbepoetin alfa exerts a cardioprotective effect in autoimmune cardiomyopathy via reduction of ER stress and activation of the PI3K/Akt and STAT3 pathways (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

darbepoetin alfa

0 references

autoimmune cardiomyopathy

1 reference

based on heuristic

inferred from title

author name string

Weike Mao

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Chikao Iwai

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Jiahao Liu

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Shey-Shing Sheu

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Michael Fu

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Chang-Seng Liang

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

27 May 2008

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Journal of Molecular and Cellular Cardiology

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

45

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

250-260

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Role of gp130-mediated signalling pathways in the heart and its impact on potential therapeutic aspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Adoptive passive transfer of rabbit beta1-adrenoceptor peptide immune cardiomyopathy into the Rag2-/- mouse: participation of the ER stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

The role of the unfolded protein response in the heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

LIF- and IL-6-induced acetylation of STAT3 at Lys-685 through PI3K/Akt activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

ER stress triggers apoptosis by activating BH3-only protein Bim

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

The JAK/STAT pathway is essential for opioid-induced cardioprotection: JAK2 as a mediator of STAT3, Akt, and GSK-3 beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Erythropoietin, modified to not stimulate red blood cell production, retains its cardioprotective properties.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Dilated cardiomyopathy caused by aberrant endoplasmic reticulum quality control in mutant KDEL receptor transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Direct evidence for a beta 1-adrenergic receptor-directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Orchestrating the unfolded protein response in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Regulation of erythropoietin-induced STAT serine phosphorylation by distinct mitogen-activated protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

An essential role of the JAK-STAT pathway in ischemic preconditioning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Stat3 as an oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

STATs and gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Requirement of serine phosphorylation for formation of STAT-promoter complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

29 September 2017

Effect of a long-term treatment with a low-dose granulocyte colony-stimulating factor on post-infarction process in the heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

27 June 2018

Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

27 June 2018

Peptides derived from cardiovascular G-protein-coupled receptors induce morphological cardiomyopathic changes in immunized rabbits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

27 June 2018

Effects of darbepoetin alpha on right and left ventricular systolic and diastolic function in anemic patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Pim-1 regulates cardiomyocyte survival downstream of Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Antibodies against the beta1-adrenergic receptor induce progressive development of cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Preventive effect of erythropoietin on cardiac dysfunction in doxorubicin-induced cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

PI3K-Akt inactivation induced CHOP expression in endoplasmic reticulum-stressed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Norepinephrine-induced oxidative stress causes PC-12 cell apoptosis by both endoplasmic reticulum stress and mitochondrial intrinsic pathway: inhibition of phosphatidylinositol 3-kinase survival pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Norepinephrine induces endoplasmic reticulum stress and downregulation of norepinephrine transporter density in PC12 cells via oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Erythropoietin protects the infant heart against ischemia-reperfusion injury by triggering multiple signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Derivatives of erythropoietin that are tissue protective but not erythropoietic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Long-acting erythropoietin: clinical studies and potential uses in neonates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Beta1-adrenoceptor antibodies induce apoptosis in adult isolated cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599925

4 September 2018

Depression of proteasome activities during the progression of cardiac dysfunction in pressure-overloaded heart of mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Cardiomyocyte apoptosis in autoimmune cardiomyopathy: mediated via endoplasmic reticulum stress and exaggerated by norepinephrine

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Low-dose erythropoietin improves cardiac function in experimental heart failure without increasing haematocrit

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Alterations in Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling in patients with end-stage dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Both proteasomes and lysosomes degrade the activated erythropoietin receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Activation of JAK/STAT pathway transduces cytoprotective signal in rat acute myocardial infarction

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Ischemia-induced STAT-1 Expression and Activation Play a Critical Role in Cardiomyocyte Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Cardioprotection by ischemic postconditioning is lost in aged and STAT3-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Reduction of inflammatory cytokine expression and oxidative damage by erythropoietin in chronic heart failure

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Protective role of endogenous erythropoietin system in nonhematopoietic cells against pressure overload-induced left ventricular dysfunction in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.05.010

7 January 2021

Identification of a neurotrophic sequence in erythropoietin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18586265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase is involved in the protection of primary cultured human erythroid precursor cells from apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18586265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.YJMCC.2008.05.010

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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