(Q46022665)

18 December 2017

title

Pim-1 regulates cardiomyocyte survival downstream of Akt. (English)

1 reference

18 December 2017

24

Piero Anversa

1 reference

18 December 2017

18

Jan Kajstura

0 references

Annarosa Leri

17

object named as

Annarosa Leri

0 references

Marcello Rota

2

object named as

Marcello Rota

0 references

Steven R Houser

22

object named as

Steven R Houser

1 reference

18 December 2017

author name string

John A Muraski

1

1 reference

18 December 2017

Marcello Rota

2

1 reference

18 December 2017

Yu Misao

3

1 reference

18 December 2017

Jenna Fransioli

4

1 reference

18 December 2017

Christopher Cottage

5

1 reference

18 December 2017

Natalie Gude

6

1 reference

18 December 2017

Grazia Esposito

7

1 reference

18 December 2017

Francesca Delucchi

8

1 reference

18 December 2017

Michael Arcarese

9

1 reference

18 December 2017

Roberto Alvarez

10

1 reference

18 December 2017

Sailay Siddiqi

11

1 reference

18 December 2017

Gregory N Emmanuel

12

1 reference

18 December 2017

Weitao Wu

13

1 reference

18 December 2017

Kimberlee Fischer

14

1 reference

18 December 2017

Joshua J Martindale

15

1 reference

18 December 2017

Christopher C Glembotski

16

1 reference

18 December 2017

Annarosa Leri

17

1 reference

18 December 2017

Jan Kajstura

18

1 reference

18 December 2017

Nancy Magnuson

19

1 reference

18 December 2017

Anton Berns

20

1 reference

18 December 2017

Remus M Beretta

21

1 reference

18 December 2017

Erik M Schaefer

23

1 reference

18 December 2017

Mark A Sussman

25

1 reference

18 December 2017

language of work or name

English

0 references

publication date

25 November 2007

1 reference

18 December 2017

published in

Nature Medicine

1 reference

18 December 2017

volume

13

1 reference

18 December 2017

issue

12

1 reference

18 December 2017

page(s)

1467-1475

1 reference

18 December 2017

https://scigraph.springernature.com/pub.10.1038/nm1671

exact match

0 references

cites work

The serine/threonine kinase Pim-1

1 reference

Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site

21 January 2018

1 reference

Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival

21 January 2018

1 reference

Tcl1 enhances Akt kinase activity and mediates its nuclear translocation

21 January 2018

1 reference

Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes

21 January 2018

1 reference

Prolactin signaling to pim-1 expression: a role for phosphatidylinositol 3-kinase

21 January 2018

1 reference

Prolactin-regulated pim-1 transcription: identification of critical promoter elements and Akt signaling

21 January 2018

1 reference

Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)

21 January 2018

1 reference

Pim-1 associates with protein complexes necessary for mitosis

21 January 2018

1 reference

Myocardial Akt activation and gender: increased nuclear activity in females versus males

21 January 2018

1 reference

Pim kinase expression is induced by LTP stimulation and required for the consolidation of enduring LTP.

21 January 2018

1 reference

Pim-1 levels determine the size of early B lymphoid compartments in bone marrow

21 January 2018

1 reference

Structure and substrate specificity of the Pim-1 kinase

21 January 2018

1 reference

Identification of the autophosphorylation sites of the Xenopus laevis Pim-1 proto-oncogene-encoded protein kinase.

21 January 2018

1 reference

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload

21 January 2018

1 reference

Interleukin-10 inhibits osteoclastogenesis by reducing NFATc1 expression and preventing its translocation to the nucleus

21 January 2018

1 reference

Opposite regulation of myc and p21waf1 transcription by STAT3 proteins

21 January 2018

1 reference

Cell cycle profiles and expressions of p21CIP1 AND P27KIP1 during myocyte development.

21 January 2018

1 reference

Embryonic heart failure in NFATc1-/- mice: novel mechanistic insights from in utero ultrasound biomicroscopy

21 January 2018

1 reference

Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression.

21 January 2018

1 reference

Dysregulation of connexins and inactivation of NFATc1 in the cardiovascular system of Nkx2-5 null mutants

21 January 2018

1 reference

The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway

21 January 2018

1 reference

Inhibition of the PI3 kinase/Akt pathway enhances doxorubicin-induced apoptotic cell death in tumor cells in a p53-dependent manner

21 January 2018

1 reference

Translational homeostasis: eukaryotic translation initiation factor 4E control of 4E-binding protein 1 and p70 S6 kinase activities

21 January 2018

1 reference

Regulation and function of IKK and IKK-related kinases

21 January 2018

1 reference

CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway

21 January 2018

1 reference

Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population.

21 January 2018

1 reference

Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy

21 January 2018

1 reference

Phenylephrine hypertrophy, Ca2+-ATPase (SERCA2), and Ca2+ signaling in neonatal rat cardiac myocytes

21 January 2018

1 reference

Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice

21 January 2018

1 reference

Doxycycline inducible expression of SERCA2a improves calcium handling and reverts cardiac dysfunction in pressure overload-induced cardiac hypertrophy

21 January 2018

1 reference

Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins

21 January 2018

1 reference

Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling

21 January 2018

1 reference

Mechanism of enhanced cardiac function in mice with hypertrophy induced by overexpressed Akt.

21 January 2018

1 reference

Nuclear targeting of Akt enhances ventricular function and myocyte contractility

21 January 2018

1 reference

Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002.

21 January 2018

1 reference

Atrial natriuretic peptide promotes cardiomyocyte survival by cGMP-dependent nuclear accumulation of zyxin and Akt.

21 January 2018

1 reference

Myofibril degeneration caused by tropomodulin overexpression leads to dilated cardiomyopathy in juvenile mice

21 January 2018

1 reference

7 January 2021

Cellular mechanisms of cardiac hypertrophy

1 reference

7 January 2021

Role of pim-1 in smooth muscle cell proliferation

1 reference

7 January 2021

Distinct types of primary cutaneous large B-cell lymphoma identified by gene expression profiling

1 reference

7 January 2021

Down-regulation of Pim-1 and Bcl-2 is accompanied with apoptosis of interleukin-6-depleted mouse B-cell hybridoma 7TD1 cells

1 reference

7 January 2021

Myocardial gene expression of leukaemia inhibitory factor, interleukin-6 and glycoprotein 130 in end-stage human heart failure

1 reference

7 January 2021

Prolactin-regulated apoptosis of Nb2 lymphoma cells: pim-1, bcl-2, and bax expression

1 reference

7 January 2021

Transcription of the SERCA2 gene is decreased in pressure-overloaded hearts: A study using in vivo direct gene transfer into living myocardium

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM1671

1 reference

18 December 2017

1 reference

18 December 2017