(Q37012007)

17 August 2017

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title

Methylenetetrahydrofolate reductase (MTHFR) variants and fluorouracil-based treatments in colorectal cancer (English)

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17 August 2017

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Marie-Christine Etienne-Grimaldi

1

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17 August 2017

Mireille Francoual

2

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17 August 2017

Jean-Louis Formento

3

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17 August 2017

Gérard Milano

4

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17 August 2017

publication date

1 November 2007

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17 August 2017

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17 August 2017

volume

8

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17 August 2017

issue

11

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17 August 2017

page(s)

1561-1566

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Adjuvant treatment of colorectal cancer at the turn of the century: European and US perspectives.

17 August 2017

cites work

1 reference

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Effect of 5,10-methylenetetrahydrofolate on the dissociation of 5-fluoro-2'-deoxyuridylate from thymidylate synthetase: evidence for an ordered mechanism

21 January 2018

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Relevance of tumoral folylpolyglutamate synthetase and reduced folates for optimal 5-fluorouracil efficacy: experimental data

21 January 2018

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Tumoral-reduced folates and clinical resistance to fluorouracil-based treatment in head and neck cancer patients

21 January 2018

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Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma

21 January 2018

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Molecular genetics of methylenetetrahydrofolate reductase deficiency

21 January 2018

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A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

21 January 2018

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A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity

21 January 2018

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A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?

21 January 2018

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Biological and clinical implications of the MTHFR C677T polymorphism

21 January 2018

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Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia

21 January 2018

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Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses

21 January 2018

1 reference

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A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.

21 January 2018

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MTHFR C677T has differential influence on risk of MSI and MSS colorectal cancer

21 January 2018

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Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate

21 January 2018

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Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity

21 January 2018

1 reference

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Expression and clinical significance of methylenetetrahydrofolate reductase in patients with colorectal cancer

21 January 2018

1 reference

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Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.11.1561

Methylenetetrahydrofolate reductase gene polymorphisms: genomic predictors of clinical response to fluoropyrimidine-based chemotherapy?

21 January 2018

1 reference

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MTHFR (C677T) polymorphisms and stage III colon cancer: response to therapy

21 January 2018

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Phase I trial of UFT/leucovorin and irinotecan in patients with advanced cancer

21 January 2018

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Pharmacogenomics of thymidylate synthase in cancer treatment

21 January 2018

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A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.11.1561

10.2217/14622416.8.11.1561

21 January 2018

Identifiers

DOI

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17 August 2017

1 reference