(Q37020095)

17 August 2017

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title

Protein engineers turned evolutionists (English)

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17 August 2017

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Sergio G Peisajovich

1

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17 August 2017

Dan S Tawfik

series ordinal

2

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17 August 2017

publication date

1 December 2007

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17 August 2017

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17 August 2017

volume

4

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17 August 2017

issue

12

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17 August 2017

page(s)

991-994

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https://scigraph.springernature.com/pub.10.1038/nmeth1207-991

17 August 2017

exact match

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cites work

Protein engineering 20 years on.

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7 January 2021

Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs

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7 January 2021

Robustness-epistasis link shapes the fitness landscape of a randomly drifting protein.

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7 January 2021

Butyramide-utilizing mutants of Pseudomonas aeruginosa 8602 which produce an amidase with altered substrate specificity.

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7 January 2021

Experimental evolution of Ebg enzyme provides clues about the evolution of catalysis and to evolutionary potential

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7 January 2021

How enzymes adapt: lessons from directed evolution

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7 January 2021

Antibody multispecificity mediated by conformational diversity

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7 January 2021

Enzyme recruitment in evolution of new function

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7 January 2021

Catalytic promiscuity and the evolution of new enzymatic activities

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7 January 2021

The Latent Promiscuity of Newly Identified Microbial Lactonases Is Linked to a Recently Diverged Phosphotriesterase†

1 reference

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7 January 2021

Evolution of enzyme superfamilies

1 reference

https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

The 'evolvability' of promiscuous protein functions

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https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

Design and evolution of new catalytic activity with an existing protein scaffold

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7 January 2021

In vitro evolution of beta-glucuronidase into a beta-galactosidase proceeds through non-specific intermediates

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7 January 2021

A despecialization step underlying evolution of a family of serine proteases

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7 January 2021

Biochemistry. Loop grafting and the origins of enzyme species.

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7 January 2021

Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity.

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7 January 2021

Dual selection enhances the signaling specificity of a variant of the quorum-sensing transcriptional activator LuxR.

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7 January 2021

Mechanistic approaches to the study of evolution: the functional synthesis

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https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

A segment of cold shock protein directs the folding of a combinatorial protein

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7 January 2021

Reconstruction of functional beta-propeller lectins via homo-oligomeric assembly of shorter fragments

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https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

The structure of the protein universe and genome evolution

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https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

Evolution of new protein topologies through multistep gene rearrangements

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https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

Probing the structural plasticity of an archaeal primordial cobaltochelatase CbiX(S)

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7 January 2021

Improving the Catalytic Activity of Candida antarctica Lipase B by Circular Permutation

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7 January 2021

Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution

1 reference

https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

Evolution favors protein mutational robustness in sufficiently large populations

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https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

DNA and the neutral theory

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https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

Neutral evolution of mutational robustness

1 reference

https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

The consensus concept for thermostability engineering of proteins: further proof of concept

1 reference

https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

Designing thermostable proteins: ancestral mutants of 3-isopropylmalate dehydrogenase designed by using a phylogenetic tree.

1 reference

https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

Protein stability promotes evolvability

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https://api.crossref.org/works/10.1038%2FNMETH1207-991

7 January 2021

Identifiers

DOI

10.1038/NMETH1207-991

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17 August 2017

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