(Q37028880)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071705%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

review article

1 reference

title

Role of TLRs/MyD88 in host resistance and pathogenesis during protozoan infection: lessons from malaria (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071705%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

0 references

0 references

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071705%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Ricardo Gazzinelli

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071705%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Catherine Ropert

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071705%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

publication date

11 December 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071705%20AND%20SRC:MED&resulttype=core&format=json

Seminars in Immunopathology

29 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071705%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071705%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071705%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

41-51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071705%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00281-007-0103-2

29 December 2019

exact match

0 references

cites work

Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection

1 reference

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Innate immune responses to human malaria: heterogeneous cytokine responses to blood-stage Plasmodium falciparum correlate with parasitological and clinical outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Aberrant Toll receptor expression and endotoxin hypersensitivity in mice lacking a functional TGF-beta 1 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Hemozoin (malarial pigment) inhibits differentiation and maturation of human monocyte-derived dendritic cells: a peroxisome proliferator-activated receptor-gamma-mediated effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Hemozoin Increases IFN-γ-Inducible Macrophage Nitric Oxide Generation Through Extracellular Signal-Regulated Kinase- and NF-κB-Dependent Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Hemozoin-inducible proinflammatory events in vivo: potential role in malaria infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Plasmodium falciparum infection causes proinflammatory priming of human TLR responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Cutting edge: the acquisition of TLR tolerance during malaria infection impacts T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

The Induction of a Type 1 Immune Response following a Trypanosoma brucei Infection Is MyD88 Dependent

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

21 January 2018

12 December 2020

Requirement of Mitogen-Activated Protein Kinases and I B Phosphorylation for Induction of Proinflammatory Cytokines Synthesis by Macrophages Indicates Functional Similarity of Receptors Triggered by Glycosylphosphatidylinositol Anchors from Parasitic

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

Regulatory role of Toll-like receptor 2 during infection with Trypanosoma cruzi

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00281-007-0103-2

21 January 2018

12 December 2020

In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection

1 reference

12 December 2020

Common and divergent immune response signaling pathways discovered in peripheral blood mononuclear cell gene expression patterns in presymptomatic and clinically apparent malaria.

1 reference

12 December 2020

The structure, biosynthesis and functions of glycosylphosphatidylinositol anchors, and the contributions of trypanosome research.

1 reference

12 December 2020

Signal transduction in host cells by a glycosylphosphatidylinositol toxin of malaria parasites

1 reference

12 December 2020

Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data

1 reference

12 December 2020

A Toll-like receptor recognizes bacterial DNA

1 reference

12 December 2020

Cerebral malaria in children: serum and cerebrospinal fluid TNF-alpha and TGF-beta levels and their relationship to clinical outcome

1 reference

12 December 2020

Toll-like receptor (TLR) polymorphisms in African children: common TLR-4 variants predispose to severe malaria

1 reference

12 December 2020

Manipulation of host innate immune responses by the malaria parasite

1 reference

12 December 2020

Innate immune recognition

1 reference

12 December 2020

Expression of toll-like receptors on antigen-presenting cells in patients with falciparum malaria.

1 reference

12 December 2020

Leishmania lipophosphoglycan (LPG) activates NK cells through toll-like receptor-2.

1 reference

12 December 2020

1 reference

12 December 2020

Common polymorphisms of toll-like receptors 4 and 9 are associated with the clinical manifestation of malaria during pregnancy

1 reference

12 December 2020

Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting

1 reference

12 December 2020

Signaling of immune system cells by glycosylphosphatidylinositol (GPI) anchor and related structures derived from parasitic protozoa.

1 reference

12 December 2020

Stimulation of B lymphocytes, macrophages, and dendritic cells by protozoan DNA.

1 reference

12 December 2020

Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria.

1 reference

12 December 2020

Impairment of macrophage functions after ingestion of Plasmodium falciparum-infected erythrocytes or isolated malarial pigment.

1 reference

12 December 2020

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

1 reference

12 December 2020

Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies

1 reference

12 December 2020

Macrophage signaling by glycosylphosphatidylinositol-anchored mucin-like glycoproteins derived from Trypanosoma cruzi trypomastigotes.

1 reference

12 December 2020

Malaria pigment paralyzes dendritic cells

1 reference

12 December 2020

Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism.

1 reference

12 December 2020

Cutting edge: IL-12 is required for the maintenance of IFN-gamma production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii

1 reference

12 December 2020

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

1 reference

12 December 2020

Roles of glycosylphosphatidylinositols of Toxoplasma gondii. Induction of tumor necrosis factor-alpha production in macrophages

1 reference

12 December 2020

IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi

1 reference

12 December 2020

Induction of experimental cerebral malaria is independent of TLR2/4/9.

1 reference

12 December 2020

Genetically Resistant Mice Lacking MyD88-Adapter Protein Display a High Susceptibility to Leishmania major Infection Associated with a Polarized Th2 Response

1 reference

12 December 2020

Acquisition of hemozoin by monocytes down-regulates interleukin-12 p40 (IL-12p40) transcripts and circulating IL-12p70 through an IL-10-dependent mechanism: in vivo and in vitro findings in severe malarial anemia

1 reference

12 December 2020

Interleukin-10 modulates susceptibility in experimental cerebral malaria.

1 reference

12 December 2020

Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection

1 reference

12 December 2020

Specificity in signal transduction among glycosylphosphatidylinositols of Plasmodium falciparum, Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp.

1 reference

12 December 2020

Endogenous IFN-gamma is required for resistance to acute Trypanosoma cruzi infection in mice.

1 reference

12 December 2020

Natural killer cells and innate immunity to protozoan pathogens

1 reference

12 December 2020

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

1 reference

12 December 2020

Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii

1 reference

12 December 2020

Pathogen recognition and innate immunity

1 reference

12 December 2020

Leukocyte activation by malarial pigment.

1 reference

12 December 2020

Glycosylphosphatidylinositol toxin of Plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelial cells by a protein tyrosine kinase-dependent and protein kinase C-dependent signaling pathway.

1 reference

12 December 2020

Modulation of host immune responses by protozoal DNA.

1 reference

12 December 2020

Involvement of IFN-gamma receptor-medicated signaling in pathology and anti-malarial immunity induced by Plasmodium berghei infection.

1 reference

12 December 2020

Virulence and disease in leishmaniasis: what is relevant for the patient?

1 reference

12 December 2020

Phagocytosis of the malarial pigment, hemozoin, impairs expression of major histocompatibility complex class II antigen, CD54, and CD11c in human monocytes

1 reference

12 December 2020

Cooperation of Toll-like receptor signals in innate immune defence

1 reference

12 December 2020

Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4

1 reference

12 December 2020

The human cytokine response to Leishmania major early after exposure to the parasite in vitro

1 reference

12 December 2020

Decreased resistance of TNF receptor p55- and p75-deficient mice to chronic toxoplasmosis despite normal activation of inducible nitric oxide synthase in vivo

1 reference

12 December 2020

Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages.

1 reference

12 December 2020

Modulation of phagolysosome biogenesis by the lipophosphoglycan of Leishmania

1 reference

12 December 2020

Murine cerebral malaria development is independent of toll-like receptor signaling

1 reference

12 December 2020

Inferences, questions and possibilities in Toll-like receptor signalling

1 reference

12 December 2020

IFNGR1 gene promoter polymorphisms and susceptibility to cerebral malaria

1 reference

12 December 2020

Trypanosoma cruzi infection in tumor necrosis factor receptor p55-deficient mice

1 reference

12 December 2020

Negative regulation of toll-like receptor-mediated immune responses

1 reference

12 December 2020

Toll-like receptor signalling

1 reference

12 December 2020

Levels of cytokines in plasma during Plasmodium falciparum malaria attacks

1 reference

12 December 2020

Glycoconjugates isolated from Trypanosoma cruzi but not from Leishmania species membranes trigger nitric oxide synthesis as well as microbicidal activity in IFN-gamma-primed macrophages

1 reference

12 December 2020

Involvement of MyD88 in host defense and the down-regulation of anti-heat shock protein 70 autoantibody formation by MyD88 in Toxoplasma gondii-infected mice.

1 reference

12 December 2020

Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function

1 reference

12 December 2020

DNA from protozoan parasites Babesia bovis, Trypanosoma cruzi, and T. brucei is mitogenic for B lymphocytes and stimulates macrophage expression of interleukin-12, tumor necrosis factor alpha, and nitric oxide

1 reference

12 December 2020

A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis

1 reference

12 December 2020

A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice

1 reference

12 December 2020

The heme moiety of malaria pigment (beta-hematin) mediates the inhibition of nitric oxide and tumor necrosis factor-alpha production by lipopolysaccharide-stimulated macrophages.

1 reference

12 December 2020

Proinflammatory activity of glycosylphosphatidylinositol anchors derived from Trypanosoma cruzi: structural and functional analyses.

1 reference

12 December 2020

Glycosylphosphatidylinositol anchors of Plasmodium falciparum: molecular characterization and naturally elicited antibody response that may provide immunity to malaria pathogenesis

1 reference

12 December 2020

Purified malaria pigment (hemozoin) enhances dendritic cell maturation and modulates the isotype of antibodies induced by a DNA vaccine

1 reference

12 December 2020

MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria.

1 reference

12 December 2020

Modulation of cytokine profiles by malaria pigment--hemozoin: role of IL-10 in suppression of proliferative responses of mitogen stimulated human PBMC.

1 reference

12 December 2020

Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity

1 reference

12 December 2020

MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll‐like receptor 2 signaling

1 reference

12 December 2020

Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in gamma interferon receptor or inducible nitric oxide synthase

1 reference

12 December 2020

Pathological role of Toll-like receptor signaling in cerebral malaria.

1 reference

12 December 2020

Re-examination of the immunosuppressive mechanisms mediating non-cure of Leishmania infection in mice

1 reference

12 December 2020

Transforming growth factor beta production is inversely correlated with severity of murine malaria infection

1 reference

12 December 2020

Innate immunity to malaria

1 reference

12 December 2020

Role of the Toll/interleukin-1 receptor signaling pathway in host resistance and pathogenesis during infection with protozoan parasites.

1 reference

12 December 2020

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha

1 reference

12 December 2020