(Q37035288)

17 August 2017

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title

Ewing sarcoma family of tumors: a model for the new era of integrated laboratory diagnostics (English)

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17 August 2017

1

Joseph D Khoury

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publication date

1 January 2008

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Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

17 August 2017

published in

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17 August 2017

volume

8

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17 August 2017

issue

1

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17 August 2017

page(s)

97-105

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Ewing's sarcoma of bone. Experience with 140 patients

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Visceral primitive peripheral neuroectodermal tumors: a clinicopathologic and molecular study

21 January 2018

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Primary cutaneous Ewing's sarcoma: immunophenotypic and molecular cytogenetic evaluation of five cases.

21 January 2018

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Primary Ewing's sarcoma/primitive neuroectodermal tumor of the kidney: a clinicopathologic and immunohistochemical analysis of 11 cases.

21 January 2018

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Pharmacological management of Ewing sarcoma family of tumours

21 January 2018

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Primary metastatic (stage IV) Ewing tumor: survival analysis of 171 patients from the EICESS studies. European Intergroup Cooperative Ewing Sarcoma Studies.

21 January 2018

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Malignant small cell tumor of the thoracopulmonary region in childhood.A distinctive clinicopathologic entity of uncertain histogenesis

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.8.1.97

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

A novel chimera gene between EWS and E1A-F, encoding the adenovirus E1A enhancer-binding protein, in extraosseous Ewing's sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

A new member of the ETS family fused to EWS in Ewing tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

A novel zinc finger gene is fused to EWS in small round cell tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Genomic structure of the EWS gene and its relationship to EWSR1, a site of tumor-associated chromosome translocation

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Expression patterns of the human sarcoma-associated genes FUS and EWS and the genomic structure of FUS

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Mechanisms of sarcoma development

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Ewing sarcoma with novel translocation t(2;16) producing an in-frame fusion of FUS and FEV.

21 January 2018

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Ets target genes: past, present and future

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Expression of Fli-1, a nuclear transcription factor, distinguishes vascular neoplasms from potential mimics

21 January 2018

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The role of Fli-1 in normal cell function and malignant transformation

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Ewing's sarcoma--routine diagnostic utilization of MIC2 analysis: a Pediatric Oncology Group/Children's Cancer Group Intergroup Study.

21 January 2018

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The MIC2 gene product: epitope mapping and structural prediction analysis define an integral membrane protein

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Molecular genetics of MIC2: a gene shared by the human X and Y chromosomes

21 January 2018

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CD99 (MIC2) expression in paediatric B-lineage leukaemia/lymphoma reflects maturation-associated patterns of normal B-lymphopoiesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Molecular mechanisms of CD99-induced caspase-independent cell death and cell-cell adhesion in Ewing's sarcoma cells: actin and zyxin as key intracellular mediators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Targeting CD99 in association with doxorubicin: an effective combined treatment for Ewing's sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Immunostaining of the p30/32MIC2 antigen and molecular detection of EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Diagnostic utility of FLI-1 monoclonal antibody and dual-colour, break-apart probe fluorescence in situ (FISH) analysis in Ewing's sarcoma/primitive neuroectodermal tumour (EWS/PNET). A comparative study with CD99 and FLI-1 polyclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Immunohistochemical detection of FLI-1 protein expression: a study of 132 round cell tumors with emphasis on CD99-positive mimics of Ewing's sarcoma/primitive neuroectodermal tumor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Relation of neurological marker expression and EWS gene fusion types in MIC2/CD99-positive tumors of the Ewing family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Variability of EWS chimaeric transcripts in Ewing tumours: a comparison of clinical and molecular data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Molecular diagnosis of Ewing tumors: improved detection of EWS-FLI-1 and EWS-ERG chimeric transcripts and rapid determination of exon combinations

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Detection of t(11;22)(q24;q12) translocation breakpoint in paraffin-embedded tissue of the Ewing's sarcoma family by nested reverse transcription-polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Performance characteristics of a reverse transcriptase-polymerase chain reaction assay for the detection of tumor-specific fusion transcripts from archival tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Differentiating Ewing's sarcoma from other round blue cell tumors using a RT-PCR translocation panel on formalin-fixed paraffin-embedded tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Identification of various exon combinations of the ews/fli1 translocation: an optimized RT-PCR method for paraffin embedded tissue -- a report by the CWS-study group

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Predictive potential of testing for bone marrow involvement in Ewing tumor patients by RT-PCR: a preliminary evaluation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Increased risk of systemic relapses associated with bone marrow micrometastasis and circulating tumor cells in localized ewing tumor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Molecular diagnosis of Ewing sarcoma/primitive neuroectodermal tumor in routinely processed tissue: a comparison of two FISH strategies and RT-PCR in malignant round cell tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Molecular diagnosis of Ewing's sarcoma/primitive neuroectodermal tumor in formalin-fixed paraffin-embedded tissues by RT-PCR and fluorescence in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Chromosomal rearrangement t(11;22) in extraskeletal Ewing's sarcoma and primitive neuroectodermal tumour analysed by fluorescence in situ hybridization using paraffin-embedded tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumour based on the detection of t(11;22) using fluorescence in situ hybridisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

Detection of EWS-FLI-1 fusion in Ewing's sarcoma/peripheral primitive neuroectodermal tumor by fluorescence in situ hybridization using formalin-fixed paraffin-embedded tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.8.1.97

21 January 2018

Identifiers

DOI

10.1586/14737159.8.1.97

1 reference

17 August 2017

1 reference