(Q37039456)

17 August 2017

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title

Beer and bread to brains and beyond: can yeast cells teach us about neurodegenerative disease? (English)

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17 August 2017

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Aaron D Gitler

1

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17 August 2017

5 December 2007

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17 August 2017

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17 August 2017

16

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17 August 2017

52-62

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17 August 2017

1

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Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs

17 August 2017

1 reference

Protein folding and misfolding

21 January 2018

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Thermotolerance in Saccharomyces cerevisiae: the Yin and Yang of trehalose

21 January 2018

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Novel insights into the mechanism of chaperone-assisted protein disaggregation

21 January 2018

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Pathways of chaperone-mediated protein folding in the cytosol

21 January 2018

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Hsp104: a weapon to combat diverse neurodegenerative disorders.

21 January 2018

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Yeast: an experimental organism for modern biology

21 January 2018

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Changing perspectives in yeast research nearly a decade after the genome sequence

21 January 2018

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21 January 2018

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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

21 January 2018

1 reference

Global analysis of protein expression in yeast

21 January 2018

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The transcriptional program of sporulation in budding yeast

21 January 2018

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Transcriptional regulatory code of a eukaryotic genome

21 January 2018

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Yeast cells provide insight into alpha-synuclein biology and pathobiology

21 January 2018

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Nosology of Parkinson's disease: looking for the way out of a quagmire

21 January 2018

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Molecular pathophysiology of Parkinson's disease

21 January 2018

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Alpha-synuclein and neurodegenerative diseases

21 January 2018

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 January 2018

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Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery

21 January 2018

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 January 2018

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alpha-Synuclein locus triplication causes Parkinson's disease

21 January 2018

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Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

21 January 2018

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Parkinson's disease: mechanisms and models

21 January 2018

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New animal models for Parkinson's disease

21 January 2018

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The role of alpha-synuclein in Parkinson's disease: insights from animal models

21 January 2018

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Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

21 January 2018

1 reference

A Drosophila model of Parkinson's disease

21 January 2018

1 reference

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 January 2018

1 reference

Torsin-mediated protection from cellular stress in the dopaminergic neurons of Caenorhabditis elegans.

21 January 2018

1 reference

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein

21 January 2018

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Alpha-synuclein targets the plasma membrane via the secretory pathway and induces toxicity in yeast

21 January 2018

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Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity

21 January 2018

1 reference

The molecular biology of Huntington's disease

21 January 2018

1 reference

Clinical Genetics, II. Huntington's disease: from the gene to pathophysiology

21 January 2018

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

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The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

21 January 2018

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Polyglutamine expansion and Huntington's disease

21 January 2018

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Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins

21 January 2018

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Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1

21 January 2018

1 reference

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

21 January 2018

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Flanking sequences profoundly alter polyglutamine toxicity in yeast

21 January 2018

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Toxic proteins in neurodegenerative disease

21 January 2018

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Mammalian prion biology: one century of evolving concepts

21 January 2018

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Oxidative damage to specific proteins in replicative and chronological-aged Saccharomyces cerevisiae: common targets and prevention by calorie restriction

21 January 2018

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Prime Time for -Synuclein

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000109759

1 reference

17 August 2017

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PubMed ID

18097160