(Q37040342)

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Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes

scientific article published on 27 June 2016

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16 March 2020

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes (English)

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16 March 2020

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Pemphigus vulgaris

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Pemphigus vulgaris

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8

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16 March 2020

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Rüdiger Eming

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16 March 2020

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Michael Hertl

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16 March 2020

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Frauke Völlner

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16 March 2020

Jawahir Ali

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16 March 2020

Nina Kurrle

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16 March 2020

Yvonne Exner

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16 March 2020

Antje Banning

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16 March 2020

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27 June 2016

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16 March 2020

Scientific Reports

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16 March 2020

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16 March 2020

28820

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16 March 2020

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Creative Commons Attribution 4.0 International

1 June 2016

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11 June 2022

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Cholinergic transactivation of the EGFR in HaCaT keratinocytes stimulates a flotillin-1 dependent MAPK-mediated transcriptional response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922016

29 September 2017

Flotillins in intercellular adhesion - from cellular physiology to human diseases

1 reference

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29 September 2017

Localization of VE-cadherin in plasmalemmal cholesterol rich microdomains and the effects of cholesterol depletion on VE-cadherin mediated cell-cell adhesion.

1 reference

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29 September 2017

Endocytic trafficking of membrane-bound cargo: a flotillin point of view.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922016

29 September 2017

Role of dynamin and clathrin in the cellular trafficking of flotillins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922016

29 September 2017

Flotillins in receptor tyrosine kinase signaling and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922016

29 September 2017

Desmosome assembly and disassembly are membrane raft-dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922016

29 September 2017

Flotillins directly interact with γ-catenin and regulate epithelial cell-cell adhesion

1 reference

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29 September 2017

Increased activity of mitogen activated protein kinase pathway in flotillin-2 knockout mouse model.

1 reference

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29 September 2017

Flotillin microdomains stabilize cadherins at cell-cell junctions

1 reference

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29 September 2017

Reggies/flotillins interact with Rab11a and SNX4 at the tubulovesicular recycling compartment and function in transferrin receptor and E-cadherin trafficking

1 reference

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29 September 2017

The C-terminal unique region of desmoglein 2 inhibits its internalization via tail-tail interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922016

29 September 2017

Galectin-3 protein regulates mobility of N-cadherin and GM1 ganglioside at cell-cell junctions of mammary carcinoma cells

1 reference

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29 September 2017

Reggies/flotillins regulate E-cadherin-mediated cell contact formation by affecting EGFR trafficking

1 reference

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29 September 2017

Functional aspects of membrane association of reggie/flotillin proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922016

29 September 2017

Flotillin-1/reggie-2 protein plays dual role in activation of receptor-tyrosine kinase/mitogen-activated protein kinase signaling.

1 reference

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29 September 2017

Desmoglein as a target in skin disease and beyond

1 reference

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Pemphigus autoimmunity: hypotheses and realities

1 reference

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The pathogenic role of autoantibodies in pemphigus vulgaris

1 reference

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29 September 2017

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922016

29 September 2017

Desmosome disassembly in response to pemphigus vulgaris IgG occurs in distinct phases and can be reversed by expression of exogenous Dsg3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922016

29 September 2017

Desmosome assembly and cell-cell adhesion are membrane raft-dependent processes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922016

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Intercellular junction assembly, dynamics, and homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922016

29 September 2017

1 reference

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A missense variant in desmoglein-2 predisposes to dilated cardiomyopathy

1 reference

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29 September 2017

Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanism

1 reference

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1 reference

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Desmoglein endocytosis and desmosome disassembly are coordinated responses to pemphigus autoantibodies

1 reference

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Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells

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Stratification-related expression of isoforms of the desmosomal cadherins in human epidermis

1 reference

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Identification of the ubiquitous human desmoglein, Dsg2, and the expression catalogue of the desmoglein subfamily of desmosomal cadherins

1 reference

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Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

1 reference

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IgG autoantibodies against desmocollin 3 in pemphigus sera induce loss of keratinocyte adhesion

1 reference

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Expression of distinct desmocollin isoforms in human epidermis

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1 reference

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Prion protein promotes growth cone development through reggie/flotillin-dependent N-cadherin trafficking.

1 reference

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1 reference

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inferred from PubMed ID database lookup

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1 reference

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Role of genetic testing in arrhythmogenic right ventricular cardiomyopathy/dysplasia

1 reference

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based on heuristic

inferred from PubMed ID database lookup

In vitro keratinocyte dissociation assay for evaluation of the pathogenicity of anti-desmoglein 3 IgG autoantibodies in pemphigus vulgaris

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Coassembly of flotillins induces formation of membrane microdomains, membrane curvature, and vesicle budding

1 reference

https://pubmed.ncbi.nlm.nih.gov/27346727

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP28820

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Europe PubMed Central

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16 March 2020

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Europe PubMed Central

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16 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27346727%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

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