(Q37040574)

English

TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer

scientific article published on 18 June 2012

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scholarly article

1 reference

Europe PubMed Central

17 August 2017

TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer (English)

1 reference

Europe PubMed Central

17 August 2017

1 reference

based on heuristic

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author name string

M K Wendt

1

1 reference

Europe PubMed Central

17 August 2017

B J Schiemann

2

1 reference

Europe PubMed Central

17 August 2017

J G Parvani

3

1 reference

Europe PubMed Central

17 August 2017

Y-H Lee

4

1 reference

Europe PubMed Central

17 August 2017

Y Kang

5

1 reference

Europe PubMed Central

17 August 2017

W P Schiemann

6

1 reference

Europe PubMed Central

17 August 2017

language of work or name

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publication date

18 June 2012

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Europe PubMed Central

17 August 2017

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Europe PubMed Central

17 August 2017

32

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Europe PubMed Central

17 August 2017

2005-2015

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Europe PubMed Central

17 August 2017

16

1 reference

Europe PubMed Central

17 August 2017

https://scigraph.springernature.com/pub.10.1038/onc.2012.230

0 references

In vivo dual substrate bioluminescent imaging.

1 reference

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Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer.

1 reference

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1 reference

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Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity

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Noncanonical TGF-β signaling during mammary tumorigenesis

1 reference

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The Src family kinase inhibitors PP2 and PP1 block TGF-beta1-mediated cellular responses by direct and differential inhibition of type I and type II TGF-beta receptors

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Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression

1 reference

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Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

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The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells

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1 reference

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Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival

1 reference

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1 reference

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Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

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Latent bone metastasis in breast cancer tied to Src-dependent survival signals

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Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

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Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness

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Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton.

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Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways

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Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.

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Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271

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Grb2 binding to Tyr284 in TbetaR-II is essential for mammary tumor growth and metastasis stimulated by TGF-beta

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Cellular characterization of a novel focal adhesion kinase inhibitor

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Genes that mediate breast cancer metastasis to lung

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1 reference

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1 reference

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Different modes and qualities of tyrosine phosphorylation of Fak and Pyk2 during epithelial-mesenchymal transdifferentiation and cell migration: analysis of specific phosphorylation events using site-directed antibodies

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1 reference

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31 March 2020

Identifiers

10.1038/ONC.2012.230

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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