(Q37044780)

17 August 2017

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title

Inhibition of microRNA with antisense oligonucleotides (English)

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17 August 2017

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Christine C Esau

1

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17 August 2017

1 January 2008

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17 August 2017

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17 August 2017

44

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17 August 2017

55-60

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17 August 2017

1

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Effective targeted gene 'knockdown' in zebrafish

17 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Inhibition of C-raf expression by antisense oligonucleotides extends heart allograft survival in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Antisense oligonucleotide-based therapeutics for cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Potent reduction of apolipoprotein B and low-density lipoprotein cholesterol by short-term administration of an antisense inhibitor of apolipoprotein B.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Improved targeting of miRNA with antisense oligonucleotides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Sequence-specific inhibition of small RNA function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

LNA-modified oligonucleotides mediate specific inhibition of microRNA function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Double-stranded regions are essential design components of potent inhibitors of RISC function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Silencing of microRNAs in vivo with 'antagomirs'

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Regulation of apoptosis by alternative pre-mRNA splicing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

The nuclear RNase III Drosha initiates microRNA processing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

The role of PACT in the RNA silencing pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Cerebellar neurodegeneration in the absence of microRNAs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Inhaled p38alpha mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Bioavailability and therapeutic activity of alicaforsen (ISIS 2302) administered as a rectal retention enema to subjects with active ulcerative colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Alicaforsen therapy in inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Spinal distribution and metabolism of 2'-O-(2-methoxyethyl)-modified oligonucleotides after intrathecal administration in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Intravitreous anti-raf-1 kinase antisense oligonucleotide as an angioinhibitory agent in porcine preretinal neovascularization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Liposome-mediated delivery of oligodeoxynucleotides in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Phase I study of liposome-encapsulated c-raf antisense oligodeoxyribonucleotide infusion in combination with radiation therapy in patients with advanced malignancies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

RNAi-mediated gene silencing in non-human primates.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Oligonucleotide conjugates as potential antisense drugs with improved uptake, biodistribution, targeted delivery, and mechanism of action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

bis-Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides are highly selectively taken up by the liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Modulation of plasma protein binding and in vivo liver cell uptake of phosphorothioate oligodeoxynucleotides by cholesterol conjugation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Enhanced hepatic uptake and bioactivity of type alpha1(I) collagen gene promoter-specific triplex-forming oligonucleotides after conjugation with cholesterol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Immunostimulatory activity of CpG containing phosphorothioate oligodeoxynucleotide is modulated by modification of a single deoxynucleoside

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

G-quartet structures in telomeric DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

Antiproliferative activity of G-quartet-forming oligonucleotides with backbone and sugar modifications.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.11.001

10.1016/J.YMETH.2007.11.001

7 January 2021

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

18158133