(Q37050391)

English

Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor.

scientific article published on 15 July 2010

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scholarly article

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7 February 2020

Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor (English)

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7 February 2020

diabetic nephropathy

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inferred from title

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7 February 2020

Josephine M. Forbes

15

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7 February 2020

Peter P Nawroth

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P P Nawroth

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7 February 2020

Angelika Bierhaus

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A Bierhaus

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7 February 2020

author name string

K C Sourris

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7 February 2020

A L Morley

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7 February 2020

A Koitka

3

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7 February 2020

P Samuel

4

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7 February 2020

M T Coughlan

5

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7 February 2020

S A Penfold

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7 February 2020

H Yamamoto

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7 February 2020

T J Allen

11

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7 February 2020

T Walther

12

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7 February 2020

T Hussain

13

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7 February 2020

M E Cooper

14

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7 February 2020

publication date

15 July 2010

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7 February 2020

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7 February 2020

53

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7 February 2020

11

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7 February 2020

2442-2451

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7 February 2020

https://scigraph.springernature.com/pub.10.1007/s00125-010-1837-2

0 references

Renal and retinal effects of enalapril and losartan in type 1 diabetes

1 reference

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29 September 2017

c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals

1 reference

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29 September 2017

RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

The renin-angiotensin system and diabetes: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Oxidative stress as a major culprit in kidney disease in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Tissue angiotensin II generating system by angiotensin-converting enzyme and chymase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

The effects of valsartan on the accumulation of circulating and renal advanced glycation end products in experimental diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Increased AT(1) receptor expression and mRNA in kidney glomeruli of AT(2) receptor gene-disrupted mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the candesartan and lisinopril microalbuminuria (CALM) study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Signal transduction from the angiotensin II AT2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Sustained hypersensitivity to angiotensin II and its mechanism in mice lacking the subtype-2 (AT2) angiotensin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Protective role of the angiotensin AT2 receptor in a renal wrap hypertension model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective Diabetes Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Possible role of P-450 metabolite of arachidonic acid in vasodilator mechanism of angiotensin II type 2 receptor in the isolated microperfused rabbit afferent arteriole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

The subtype 2 angiotensin receptor regulates renal prostaglandin F2 alpha formation in conscious rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

29 September 2017

AT2 receptor-mediated vasodilation in the mouse heart depends on AT1A receptor activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

27 June 2018

Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

27 June 2018

Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

27 June 2018

Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: three randomized trials.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

4 September 2018

Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

4 September 2018

Angiotensin II upregulates RAGE expression on podocytes: role of AT2 receptors

1 reference

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RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low-molecular weight heparin

1 reference

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4 September 2018

A severe diabetic nephropathy model with early development of nodule-like lesions induced by megsin overexpression in RAGE/iNOS transgenic mice

1 reference

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4 September 2018

Telmisartan inhibits expression of a receptor for advanced glycation end products (RAGE) in angiotensin-II-exposed endothelial cells and decreases serum levels of soluble RAGE in patients with essential hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

4 September 2018

Interactions between renin angiotensin system and advanced glycation in the kidney.

1 reference

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4 September 2018

AGEs activate mesangial TGF-beta-Smad signaling via an angiotensin II type I receptor interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

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Elevated blood pressure in normotensive rats produced by 'knockdown' of the angiotensin type 2 receptor

1 reference

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4 September 2018

Utility of endogenous creatinine clearance as a measure of renal function in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

4 September 2018

Prophylactic and therapeutic treatments with AT 1 and AT 2 receptor antagonists and their effects on changes in the severity of pancreatitis

1 reference

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4 September 2018

Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

4 September 2018

Role of AT2 receptor in the brain in regulation of blood pressure and water intake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

4 September 2018

Angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors lower in vitro the formation of advanced glycation end products: biochemical mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

4 September 2018

The renin–angiotensin system and diabetes: An update

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1837-2

21 January 2018

The losartan renal protection study--rationale, study design and baseline characteristics of RENAAL (Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4926314

20 October 2018

Accelerated fibrosis and collagen deposition develop in the renal interstitium of angiotensin type 2 receptor null mutant mice during ureteral obstruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631980

12 December 2020

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inferred from PubMed ID database lookup

Deletion of Nicotinamide Nucleotide Transhydrogenase: A New Quantitive Trait Locus Accounting for Glucose Intolerance in C57BL/6J Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631980

12 December 2020

based on heuristic

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ANG II induces c-Jun NH2-terminal kinase activation and proliferation of human mesangial cells via redox-sensitive transactivation of the EGFR

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of AT2 receptor blockade on the pathogenesis of renal fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination Therapy with the Advanced Glycation End Product Cross-Link Breaker, Alagebrium, and Angiotensin Converting Enzyme Inhibitors in Diabetes: Synergy or Redundancy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse models of diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-010-1837-2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20631980%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20631980%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20631980%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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