(Q37051351)

17 August 2017

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title

Klotho as a regulator of oxidative stress and senescence (English)

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17 August 2017

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Makoto Kuro-o

1

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17 August 2017

publication date

1 March 2008

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17 August 2017

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17 August 2017

volume

389

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17 August 2017

issue

3

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17 August 2017

page(s)

233-241

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Klotho insufficiency causes decrease of ribosomal RNA gene transcription activity, cytoplasmic RNA and rough ER in the spinal anterior horn cells.

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Prolonged longevity of hypopituitary dwarf mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Extended longevity in mice lacking the insulin receptor in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Functional interaction between beta-catenin and FOXO in oxidative stress signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Amelioration of progressive renal injury by genetic manipulation of Klotho gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Ablation of vitamin D signaling rescues bone, mineral, and glucose homeostasis in Fgf-23 deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Calcium absorption across epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

alpha-Klotho as a regulator of calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Evolution of the Fgf and Fgfr gene families

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Expression of Klotho protein in the inner ear.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

A C. elegans mutant that lives twice as long as wild type

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

FGF-21 as a novel metabolic regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Suppression of aging in mice by the hormone Klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Regulation of fibroblast growth factor-23 signaling by klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Calpain as an effector of the Gq signaling pathway for inhibition of Wnt/beta -catenin-regulated cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Liver-specific activities of FGF19 require Klotho beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Augmented Wnt signaling in a mammalian model of accelerated aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Emerging role of fibroblast growth factor 23 in a bone-kidney axis regulating systemic phosphate homeostasis and extracellular matrix mineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Regulation of multiple ageing-like phenotypes by inducible klotho gene expression in klotho mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Structural basis for fibroblast growth factor receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Klotho protein protects against endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Angiogenesis and vasculogenesis are impaired in the precocious-aging klotho mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Klotho reduces apoptosis in experimental ischaemic acute renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Brain IRS2 signaling coordinates life span and nutrient homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

The endocrine regulation of aging by insulin-like signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Klotho is a novel beta-glucuronidase capable of hydrolyzing steroid beta-glucuronides

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Impaired regulation of gonadotropins leads to the atrophy of the female reproductive system in klotho-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Klotho converts canonical FGF receptor into a specific receptor for FGF23

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Co-receptor requirements for fibroblast growth factor-19 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Regulation of oxidative stress by the anti-aging hormone klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

Anti-apoptotic and anti-senescence effects of Klotho on vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2008.028

21 January 2018

Identifiers

DOI

10.1515/BC.2008.028

1 reference

release_42qptgpexnditpjdylye6pv6nq

17 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/42qptgpexnditpjdylye6pv6nq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference