(Q37055039)

English

Mast cell-restricted, tetramer-forming tryptases induce aggrecanolysis in articular cartilage by activating matrix metalloproteinase-3 and -13 zymogens

scientific article published on 24 June 2013

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

Mast cell-restricted, tetramer-forming tryptases induce aggrecanolysis in articular cartilage by activating matrix metalloproteinase-3 and -13 zymogens (English)

1 reference

Europe PubMed Central

18 August 2017

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

object named as

Roberto Adachi

4

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object named as

Amanda J Fosang

3

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author name string

Natalia J Magarinos

1

1 reference

Europe PubMed Central

18 August 2017

Katherine J Bryant

2

1 reference

Europe PubMed Central

18 August 2017

Richard L Stevens

5

1 reference

Europe PubMed Central

18 August 2017

H Patrick McNeil

6

1 reference

Europe PubMed Central

18 August 2017

language of work or name

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publication date

24 June 2013

1 reference

Europe PubMed Central

18 August 2017

number of pages

9

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inferred from page(s)

Journal of Immunology

1 reference

Europe PubMed Central

18 August 2017

191

1 reference

Europe PubMed Central

18 August 2017

3

1 reference

Europe PubMed Central

18 August 2017

1404-1412

1 reference

Europe PubMed Central

18 August 2017

Ras guanine nucleotide-releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Baseline serum MMP-3 levels in patients with Rheumatoid Arthritis are still independently predictive of radiographic progression in a longitudinal observational cohort at 8 years follow up

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Mouse mast cell tryptase mMCP-6 is a critical link between adaptive and innate immunity in the chronic phase of Trichinella spiralis infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Mast cell-restricted tryptases: structure and function in inflammation and pathogen defense.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

The roles of substrate thermal stability and P2 and P1' subsite identity on matrix metalloproteinase triple-helical peptidase activity and collagen specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Human mast cell-derived gelatinase B (matrix metalloproteinase-9) is regulated by inflammatory cytokines: role in cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Matrix metalloproteinases are not essential for aggrecan turnover during normal skeletal growth and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Mast cells: a cellular link between autoantibodies and inflammatory arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Genetic deficiency of human mast cell alpha-tryptase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Synovial mast cell responses during clinical improvement in early rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Distribution, activation and tryptase/chymase phenotype of mast cells in the rheumatoid lesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Mast cells, cytokines, and metalloproteinases at the rheumatoid lesion: dual immunolocalisation studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Production and characterization of monoclonal antibodies directed against connective tissue proteoglycans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Cloning and characterization of a second complementary DNA for human tryptase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

The role of stromelysin in the cartilage destruction that accompanies inflammatory arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Cleavage of cartilage proteoglycan between G1 and G2 domains by stromelysins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Isolation, characterization, and transcription of the gene encoding mouse mast cell protease 7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

29 September 2017

Human mast cell beta-tryptase is a gelatinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

27 June 2018

Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

27 June 2018

Automation of 1,9-dimethylmethylene blue dye-binding assay for sulfated glycosaminoglycans with application to cartilage microcultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

27 June 2018

Sites of stromelysin cleavage in collagen types II, IX, X, and XI of cartilage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

27 June 2018

Investigating ADAMTS-mediated aggrecanolysis in mouse cartilage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

4 September 2018

The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

4 September 2018

The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

4 September 2018

Synovial tissue protease gene expression and joint erosions in early rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

4 September 2018

Activation mechanisms of matrix metalloproteinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

4 September 2018

Cloning of the cDNA and gene of mouse mast cell protease-6. Transcription by progenitor mast cells and mast cells of the connective tissue subclass.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

4 September 2018

Neoepitope Antibodies Against MMP-Cleaved and Aggrecanase-Cleaved Aggrecan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727140

4 December 2018

Tryptase from human pulmonary mast cells. Purification and characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and functional studies of rheumatoid synovial mast cells. Activation by secretagogues, anti-IgE, and a histamine-releasing lymphokine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast cell numbers and histamine levels in synovial fluids from patients with diverse arthritides

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of mast cells in antigen induced arthritis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of rat cutaneous mast cells with Percoll density centrifugation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan. Evidence for proteolysis at this site in vivo in human articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serosal mast cells maintain their viability and promote the metabolism of cartilage proteoglycans when cocultured with chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of cartilage aggrecan by collagenase-3 (MMP-13)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast cell responses in rheumatoid synovium. Association of the MCTC subset with matrix turnover and clinical progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast cell activation in arthritis: detection of alpha- and beta-tryptase, histamine and eosinophil cationic protein in synovial fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast cell subpopulations in the synovial tissue of patients with osteoarthritis: selective increase in numbers of tryptase-positive, chymase-negative mast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of aggrecan at the Asn341-Phe342 site coincides with the initiation of collagen damage in murine antigen-induced arthritis: a pivotal role for stromelysin 1 in matrix metalloproteinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/23797671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1300856

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

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