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Mechanisms and molecular probes of sirtuins.
scientific article published on October 2008
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Europe PubMed Central
PMC publication ID
2626554
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940661%20AND%20SRC:MED&resulttype=core&format=json
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24 December 2019
review article
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title
Mechanisms and molecular probes of sirtuins
(English)
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Europe PubMed Central
PMC publication ID
2626554
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940661%20AND%20SRC:MED&resulttype=core&format=json
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24 December 2019
author
Brian Smith
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1
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Europe PubMed Central
PMC publication ID
2626554
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24 December 2019
author name string
William C Hallows
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2
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Europe PubMed Central
PMC publication ID
2626554
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940661%20AND%20SRC:MED&resulttype=core&format=json
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24 December 2019
John M Denu
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3
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2626554
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940661%20AND%20SRC:MED&resulttype=core&format=json
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24 December 2019
publication date
1 October 2008
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24 December 2019
published in
Chemistry and Biology
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stated in
Europe PubMed Central
PMC publication ID
2626554
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940661%20AND%20SRC:MED&resulttype=core&format=json
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24 December 2019
volume
15
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Europe PubMed Central
PMC publication ID
2626554
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940661%20AND%20SRC:MED&resulttype=core&format=json
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24 December 2019
issue
10
1 reference
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Europe PubMed Central
PMC publication ID
2626554
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940661%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 December 2019
page(s)
1002-1013
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PMC publication ID
2626554
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24 December 2019
cites work
Structural Insights into Intermediate Steps in the Sir2 Deacetylation Reaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Molecular characterization of propionyllysines in non-histone proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Development of a fluorescence polarization based assay for histone deacetylase ligand discovery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Analysis of DBC1 and its homologs suggests a potential mechanism for regulation of sirtuin domain deacetylases by NAD metabolites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Sirtuins: novel targets for metabolic disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Inhibitors of NAD+ dependent histone deacetylases (sirtuins).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
The Sirtuin family: therapeutic targets to treat diseases of aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Negative regulation of the deacetylase SIRT1 by DBC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
DBC1 is a negative regulator of SIRT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Optimization of activity-based probes for proteomic profiling of histone deacetylase complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
A therapeutic role for sirtuins in diseases of aging?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
A spectrophotometric assay for histone deacetylase 8.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
A homogeneous cellular histone deacetylase assay suitable for compound profiling and robotic screening
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
N-lysine propionylation controls the activity of propionyl-CoA synthetase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Substrate activity screening (SAS): a general procedure for the preparation and screening of a fragment-based non-peptidic protease substrate library for inhibitor discovery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Lysine propionylation and butyrylation are novel post-translational modifications in histones
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Activity-based probes for proteomic profiling of histone deacetylase complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Catalytic mechanism of a MYST family histone acetyltransferase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Caspase-mediated changes in Sir2alpha during apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
The biochemistry of sirtuins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Small molecule regulation of Sir2 protein deacetylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Mechanism of human SIRT1 activation by resveratrol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Substrate-specific activation of sirtuins by resveratrol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Members of the histone deacetylase superfamily differ in substrate specificity towards small synthetic substrates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
A chromosomal SIR2 homologue with both histone NAD-dependent ADP-ribosyltransferase and deacetylase activities is involved in DNA repair in Trypanosoma brucei
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Tissue-specific regulation of SIRT1 by calorie restriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
29 September 2017
Transition State Structure for the Hydrolysis of NAD Catalyzed by Diphtheria Toxin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
27 June 2018
Plasmodium falciparum Sir2 is an NAD+-dependent deacetylase and an acetyllysine-dependent and acetyllysine-independent NAD+ glycohydrolase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
27 June 2018
Where in the cell is SIRT3?--functional localization of an NAD+-dependent protein deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
27 June 2018
Sir2 deacetylases exhibit nucleophilic participation of acetyl-lysine in NAD+ cleavage.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
27 June 2018
Pertussis toxin: transition state analysis for ADP-ribosylation of G-protein peptide alphai3C20.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
27 June 2018
Substituting N(epsilon)-thioacetyl-lysine for N(epsilon)-acetyl-lysine in peptide substrates as a general approach to inhibiting human NAD(+)-dependent protein deacetylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Characterization of the binding properties of SIRT2 inhibitors with a N-(3-phenylpropenoyl)-glycine tryptamide backbone.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Biochemical characterization of Plasmodium falciparum Sir2, a NAD+-dependent deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Plasmodium falciparum Sir2: an unusual sirtuin with dual histone deacetylase and ADP-ribosyltransferase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Catalase alleviates cardiomyocyte dysfunction in diabetes: role of Akt, Forkhead transcriptional factor and silent information regulator 2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Use of substrate analogs and mutagenesis to study substrate binding and catalysis in the Sir2 family of NAD-dependent protein deacetylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Subtype selective substrates for histone deacetylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Structural basis for the mechanism and regulation of Sir2 enzymes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Transition state structure for ADP-ribosylation of eukaryotic elongation factor 2 catalyzed by diphtheria toxin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Mechanism of Nicotinamide Inhibition and Transglycosidation by Sir2 Histone/Protein Deacetylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Fluorogenic substrate [Ala-Pro]2-cresyl violet but not Ala-Pro-rhodamine 110 is cleaved specifically by DPPIV activity: a study in living Jurkat cells and CD26/DPPIV-transfected Jurkat cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD+-dependent histone/protein deacetylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Kinetic isotope effect characterization of the transition state for oxidized nicotinamide adenine dinucleotide hydrolysis by pertussis toxin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 September 2018
Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD+ and Acetylated Peptide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 December 2018
Highly Potent and Selective Histone Deacetylase 6 Inhibitors Designed Based on a Small-Molecular Substrate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626554
retrieved
4 December 2018
Acetylation-dependent ADP-ribosylation by Trypanosoma brucei Sir2
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18940661
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Vitamins and aging: pathways to NAD+ synthesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18940661
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18940661
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Detection of histone deacetylase inhibition by noninvasive magnetic resonance spectroscopy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18940661
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Metabolite of SIR2 reaction modulates TRPM2 ion channel
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18940661
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nepsilon-thioacetyl-lysine: a multi-facet functional probe for enzymatic protein lysine Nepsilon-deacetylation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18940661
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transition-state structure for the ADP-ribosylation of recombinant Gialpha1 subunits by pertussis toxin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18940661
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CHEMBIOL.2008.09.009
1 reference
stated in
Europe PubMed Central
PMC publication ID
2626554
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940661%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 December 2019
PMC publication ID
2626554
1 reference
stated in
Europe PubMed Central
PMC publication ID
2626554
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940661%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 December 2019
PubMed publication ID
18940661
1 reference
stated in
Europe PubMed Central
PMC publication ID
2626554
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940661%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 December 2019
ResearchGate publication ID
23404781
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