(Q37061560)

18 August 2017

1 reference

title

Genes encoding longevity: from model organisms to humans (English)

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18 August 2017

1 reference

5

P Eline Slagboom

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18 August 2017

6

Rudi G J Westendorp

1 reference

18 August 2017

4

Bas J Zwaan

1 reference

18 August 2017

2

Simon P Mooijaart

1 reference

18 August 2017

3

Diana van Heemst

1 reference

18 August 2017

Maris Kuningas

1

1 reference

18 August 2017

15 January 2008

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18 August 2017

1 reference

18 August 2017

7

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18 August 2017

270-280

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18 August 2017

2

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Regulation of life-span by germ-line stem cells in Caenorhabditis elegans

18 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Association of human aging with a functional variant of klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Association between a functional variant of the KLOTHO gene and high-density lipoprotein cholesterol, blood pressure, stroke, and longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

The role of p53-mediated apoptosis as a crucial anti-tumor response to genomic instability: lessons from mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Methuselah life history in a variety of conditions, implications for the use of mutants in longevity research

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Unique lipoprotein phenotype and genotype associated with exceptional longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

New tricks of an old molecule: lifespan regulation by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Resveratrol improves health and survival of mice on a high-calorie diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Superoxide dismutase 1 knock-down induces senescence in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

MicroRNA control of lifespan and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Werner syndrome protein 1367 variants and disposition towards coronary artery disease in Caucasian patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Calorie restriction, SIRT1 and metabolism: understanding longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Almost all human genes resulted from ancient duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Dwarf mice and the ageing process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Cancer and ageing: rival demons?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Population stratification and spurious allelic association

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

FOXO transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Chromosomal instability at common fragile sites in Seckel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

The catalase -262C/T promoter polymorphism and aging phenotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Dietary restriction in long-lived dwarf flies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Cancer in xeroderma pigmentosum and related disorders of DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

A phylogenomic study of DNA repair genes, proteins, and processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Sirtuin 1 (SIRT1) sequence variation is not associated with exceptional human longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Growth hormone and prolactin--molecular and functional evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Epigenetics and aging: the targets and the marks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Ten years of life: Is it a matter of choice?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Role of insulin-like signalling in Drosophila lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Role of duplicate genes in genetic robustness against null mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Aging and genome maintenance: lessons from the mouse?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Reduced insulin/IGF-1 signalling and human longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Variation in the human TP53 gene affects old age survival and cancer mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Lipoprotein particle profiles mark familial and sporadic human longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Genetic influence on human lifespan and longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

21 January 2018

DNA repair mechanisms

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Signals from the reproductive system regulate the lifespan of C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Modulated microRNA expression during adult lifespan in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Analysis of FOXO1A as a candidate gene for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Phenotypic analysis of seizure-prone mice lacking L-isoaspartate (D-aspartate) O-methyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Multilocus analysis of SNP and metabolic data within a given pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

SIRT1 gene, age-related diseases, and mortality: the Leiden 85-plus study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Suppression of aging in mice by the hormone Klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Determination of life-span in Caenorhabditis elegans by four clock genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Do deficiencies in growth hormone and insulin-like growth factor-1 (IGF-1) shorten or prolong longevity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

The evolutionary origin of complex features

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Transcription regulation and animal diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

The SOD2 Val/Val genotype enhances the risk of nonsmall cell lung carcinoma by p53 and XRCC1 polymorphisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

21 January 2018

Evolution of novel genes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Limited accumulation of damaged proteins in l-isoaspartyl (D-aspartyl) O-methyltransferase-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

The nuclear receptor superfamily: the second decade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Genes, environment and the value of prospective cohort studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Heritability of life span in the Old Order Amish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

ApoE plasma levels and risk of cardiovascular mortality in old age

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Plasma levels of apolipoprotein E and cognitive function in old age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Reproduction and longevity: secrets revealed by C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Molecular bases of progeroid syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Insulin, insulin-like growth factor-I (IGF-I) and glucagon: the evolution of their receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Demography. Broken limits to life expectancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

In vivo mutagenesis of the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Serum levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 in healthy centenarians: relationship with plasma leptin and lipid concentrations, insulin action, and cognitive function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Sex and death: what is the connection?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Obesity in Adulthood and Its Consequences for Life Expectancy: A Life-Table Analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Life-long sustained mortality advantage of siblings of centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

p53 polymorphic variants at codon 72 exert different effects on cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Control of Caenorhabditis elegans life history by nuclear receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Extension of murine life span by overexpression of catalase targeted to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

A delayed wave of death from reproduction in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Simultaneous overexpression of copper- and zinc-containing superoxide dismutase and catalase retards age-related oxidative damage and increases metabolic potential in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Evolution of complexity in signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Effect of DNA Repair on Aging of Transgenic Drosophila melanogaster: I. mei-41 Locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Is the Val16Ala manganese superoxide dismutase polymorphism associated with the aging process?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

p53 mutant mice that display early ageing-associated phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Plasma levels of apolipoprotein E and risk of stroke in old age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Evolution of lifespan in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

MicroRNA, the putative molecular control for mid-life decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Liver X receptors as integrators of metabolic and inflammatory signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Human longevity at the cost of reproductive success

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

Benchmarks for ageing studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00366.X

10.1111/J.1474-9726.2008.00366.X

21 January 2018

Identifiers

DOI

1 reference

18 August 2017

1 reference

PubMed ID

18208581