(Q37063570)

18 August 2017

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title

Click chemistry and medicinal chemistry: a case of "cyclo-addiction". (English)

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18 August 2017

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A D Moorhouse

1

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18 August 2017

J E Moses

series ordinal

2

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18 August 2017

publication date

1 May 2008

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18 August 2017

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18 August 2017

volume

3

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18 August 2017

issue

5

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18 August 2017

page(s)

715-723

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Click-Chemie: diverse chemische Funktionalität mit einer Handvoll guter Reaktionen

18 August 2017

cites work

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The growing applications of click chemistry

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1,3-dipolar cycloadditions of azides and alkynes: a universal ligation tool in polymer and materials science.

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Triazole: the keystone in glycosylated molecular architectures constructed by a click reaction

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Peptidomimetics via copper-catalyzed azide-alkyne cycloadditions.

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Click Chemistry - What’s in a Name? Triazole Synthesis and Beyond

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Azide/Alkyne-'Click' Reactions: Applications in Material Science and Organic Synthesis

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CuI-Catalyzed Alkyne-Azide “Click” Cycloadditions from a Mechanistic and Synthetic Perspective

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The growing impact of click chemistry on drug discovery

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A two stage click-based library of protein tyrosine phosphatase inhibitors

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Metal catalyzed diazo transfer for the synthesis of azides from amines

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One-pot procedure for diazo transfer and azide-alkyne cycloaddition: triazole linkages from amines

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A microwave-assisted click chemistry synthesis of 1,4-disubstituted 1,2,3-triazoles via a copper(I)-catalyzed three-component reaction

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Efficient conversion of aromatic amines into azides: a one-pot synthesis of triazole linkages

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Syntheses of triazole-modified zanamivir analogues via click chemistry and anti-AIV activities.

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Synthesis and characterization of the 7-(4-aminomethyl-1H-1,2,3-triazol-1-yl) analogue of kabiramide C

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Diversifying vancomycin via chemoenzymatic strategies.

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Syntheses and biological activity of bisdaunorubicins

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Multisite Modification of Neomycin B: Combined Mitsunobu and Click Chemistry Approach

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Click linker: efficient and high-yielding synthesis of a new family of SPOS resins by 1,3-dipolar cycloaddition

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Click chemistry based solid phase supported synthesis of dopaminergic phenylacetylenes

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Click chemistry on solid phase: parallel synthesis of N-benzyltriazole carboxamides as super-potent G-protein coupled receptor ligands

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Chemical library synthesis using convergent approaches

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Rapid assembly and in situ screening of bidentate inhibitors of protein tyrosine phosphatases

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Rapid assembly of matrix metalloprotease inhibitors using click chemistry.

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Microtiter plate based chemistry and in situ screening: a useful approach for rapid inhibitor discovery

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A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry

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7 January 2021

Rapid Diversity‐Oriented Synthesis in Microtiter Plates for In Situ Screening of HIV Protease Inhibitors

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7 January 2021

Virtual combinatorial libraries: dynamic generation of molecular and supramolecular diversity by self-assembly

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7 January 2021

Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase

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7 January 2021

Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks

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7 January 2021

Inhibitors of HIV-1 protease by using in situ click chemistry

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7 January 2021

Integrated microfluidics for parallel screening of an in situ click chemistry library

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7 January 2021

Stabilization of G-Quadruplex DNA by Highly Selective Ligands via Click Chemistry

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7 January 2021

Rationally designed nucleoside antibiotics that inhibit siderophore biosynthesis of Mycobacterium tuberculosis

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7 January 2021

Rapid synthesis of triazole-modified resveratrol analogues via click chemistry.

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7 January 2021

Design, synthesis, and preliminary biological evaluation of a novel triazole analogue of ceramide

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7 January 2021

1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors

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7 January 2021

Application of azide-alkyne cycloaddition 'click chemistry' for the synthesis of Grb2 SH2 domain-binding macrocycles

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7 January 2021

Design and synthesis of a new, conformationally constrained, macrocyclic small-molecule inhibitor of STAT3 via 'click chemistry'

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7 January 2021

Identifiers

DOI

10.1002/CMDC.200700334

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18 August 2017

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