(Q37063743)

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Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology.

scientific article published on 06 May 2013

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29 February 2020

Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology (English)

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29 February 2020

Artak Tovmasyan

1

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29 February 2020

2

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29 February 2020

Julio S Reboucas

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29 February 2020

Ludmil T. Benov

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29 February 2020

Ines Batinic-Haberle

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Ines Batinic-Haberle

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29 February 2020

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Huaxin Sheng

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29 February 2020

MiaoMiao Lu

4

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29 February 2020

Zrinka Rajic

5

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29 February 2020

David S Warner

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29 February 2020

Ivan Spasojevic

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29 February 2020

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6 May 2013

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29 February 2020

Inorganic Chemistry

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29 February 2020

52

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29 February 2020

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29 February 2020

5677-5691

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29 February 2020

Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.

1 reference

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29 September 2017

Catalytic peroxynitrite decomposition improves reperfusion injury after heart transplantation

1 reference

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29 September 2017

A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity

1 reference

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29 September 2017

Battles with iron: manganese in oxidative stress protection

1 reference

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29 September 2017

Manganese superoxide dismutase, MnSOD and its mimics

1 reference

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29 September 2017

Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate

1 reference

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29 September 2017

Effects of FP15, a peroxynitrite decomposition catalyst on cardiac and pulmonary function after cardiopulmonary bypass

1 reference

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29 September 2017

Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

1 reference

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29 September 2017

Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

The peroxynitrite catalyst WW-85 improves microcirculation in ovine smoke inhalation injury and septic shock

1 reference

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29 September 2017

Effects of a potent peroxynitrite decomposition catalyst in murine models of endotoxemia and sepsis

1 reference

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29 September 2017

Beneficial pulmonary effects of a metalloporphyrinic peroxynitrite decomposition catalyst in burn and smoke inhalation injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site

1 reference

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29 September 2017

Overcoming the heme paradox: heme toxicity and tolerance in bacterial pathogens

1 reference

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29 September 2017

The peroxynitrite catalyst WW-85 improves pulmonary function in ovine septic shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities

1 reference

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29 September 2017

Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Bacterial heme-transport proteins and their heme-coordination modes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

High-valent iron in chemical and biological oxidations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Mechanism of oxidation reactions catalyzed by cytochrome p450 enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Iron uptake by Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Iron uptake mechanisms and their regulation in pathogenic bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Manganese(III) biliverdin IX dimethyl ester: a powerful catalytic scavenger of superoxide employing the Mn(III)/Mn(IV) redox couple

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Bacterial solutions to the iron-supply problem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Characterization of the ferrous iron uptake system of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Lethal oxidative damage and mutagenesis are generated by iron in delta fur mutants of Escherichia coli: protective role of superoxide dismutase

1 reference

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29 September 2017

Mutagenesis and stress responses induced in Escherichia coli by hydrogen peroxide

1 reference

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29 September 2017

Molecular mechanism of regulation of siderophore-mediated iron assimilation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

29 September 2017

Fumarase C, the stable fumarase of Escherichia coli, is controlled by the soxRS regulon

1 reference

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29 September 2017

A structural model for heme in high-spin ferric hemoproteins. Iron atom centering, porphinato core expansion, and molecular stereochemistry of high-spin diaquo(meso-tetraphenylporphinato)iron(III) perchlorate

1 reference

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29 September 2017

Ferric uptake regulation protein acts as a repressor, employing iron (II) as a cofactor to bind the operator of an iron transport operon in Escherichia coli

1 reference

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29 September 2017

Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: potentiometric, spectrophotometric and spectroelectrochemical study of protolytic and redox equilibria.

1 reference

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27 June 2018

High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

27 June 2018

Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes

1 reference

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27 June 2018

Reactions of Manganese Porphyrins with Peroxynitrite and Carbonate Radical Anion

1 reference

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27 June 2018

alpha, beta-Dihydroxyisovalerate dehydratase. A superoxide-sensitive enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

27 June 2018

Superoxide sensitivity of the Escherichia coli 6-phosphogluconate dehydratase

1 reference

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27 June 2018

Superoxide sensitivity of the Escherichia coli aconitase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

27 June 2018

Thermal stability of the prototypical Mn porphyrin-based superoxide dismutase mimic and potent oxidative-stress redox modulator Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin chloride, MnTE-2-PyP(5+).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

4 September 2018

Metalloporphyrin synergizes with ascorbic acid to inhibit cancer cell growth through fenton chemistry

1 reference

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4 September 2018

Effects of a metalloporphyrinic peroxynitrite decomposition catalyst, ww-85, in a mouse model of spinal cord injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

4 September 2018

Oxoiron(IV) porphyrin pi-cation radical complexes with a chameleon behavior in cytochrome P450 model reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

4 September 2018

Protective mechanisms of a metalloporphyrinic peroxynitrite decomposition catalyst, WW85, in rat cardiac transplants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

4 September 2018

New class of potent catalysts of O2.-dismutation. Mn(III) ortho-methoxyethylpyridyl- and di-ortho-methoxyethylimidazolylporphyrins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

4 September 2018

Hemodynamic effects of metalloporphyrin catalytic antioxidants: structure-activity relationships and species specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

4 September 2018

Electrostatic contribution in the catalysis of O2*- dismutation by superoxide dismutase mimics. MnIIITE-2-PyP5+ versus MnIIIBr8T-2-PyP+.

1 reference

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4 September 2018

Anionic ligand effect on the nature of epoxidizing intermediates in iron porphyrin complex-catalyzed epoxidation reactions

1 reference

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4 September 2018

Manganese supplementation relieves the phenotypic deficits seen in superoxide-dismutase-null Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

4 September 2018

The inactivation of Fe-S cluster containing hydro-lyases by superoxide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731146

4 September 2018

Dihydroxy-acid dehydratase, a [4Fe-4S] cluster-containing enzyme in Escherichia coli: effects of intracellular superoxide dismutase on its inactivation by oxidant stress.

1 reference

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4 September 2018

Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants

1 reference

https://pubmed.ncbi.nlm.nih.gov/23646875

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New approach to the activation of anti-cancer pro-drugs by metalloporphyrin-based cytochrome P450 mimics in all-aqueous biologically relevant system

1 reference

https://pubmed.ncbi.nlm.nih.gov/23646875

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic

1 reference

https://pubmed.ncbi.nlm.nih.gov/23646875

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The peroxynitrite decomposition catalyst FP15 improves ageing-associated cardiac and vascular dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/23646875

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth in iron-enriched medium partially compensates Escherichia coli for the lack of manganese and iron superoxide dismutase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23646875

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrochemistry of P450cin: new insights into P450 electron transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23646875

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of the auxotrophy for sulfur-containing amino acids imposed upon Escherichia coli by superoxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/23646875

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Why superoxide imposes an aromatic amino acid auxotrophy on Escherichia coli. The transketolase connection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23646875

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypersensitive radical probes and the mechanisms of cytochrome P450-catalyzed hydroxylation reactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23646875

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/IC3012519

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23646875%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PMC publication ID

1 reference

Europe PubMed Central

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29 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23646875%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

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