(Q37072970)

English

Variation in NPC1, the gene encoding Niemann-Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population

scientific article published on 24 September 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Variation in NPC1, the gene encoding Niemann-Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Alzheimer's disease

0 references

Jacek Kuźnicki

object named as

Jacek Kuznicki

8

0 references

Małgorzata Mossakowska

5

object named as

Malgorzata Mossakowska

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Maria Barcikowska

7

object named as

Maria Barcikowska

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Aleksandra Szybinska

4

object named as

Aleksandra Szybinska

1 reference

Europe PubMed Central

18 August 2017

PMC publication ID

author name string

Robert P Erickson

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Katherine Larson-Thomé

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Lyndon Weberg

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Maria Styczynska

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

0 references

publication date

24 September 2008

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Neuroscience Letters

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

447

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

2-3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

153-157

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Astrocyte-only Npc1 reduces neuronal cholesterol and triples life span of Npc1-/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630970

29 September 2017

Analysis and application of European genetic substructure using 300 K SNP information

1 reference

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29 September 2017

A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase

1 reference

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29 September 2017

The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Abeta generation in vivo

1 reference

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29 September 2017

Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways

1 reference

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29 September 2017

Cholesterol, statins and dementia.

1 reference

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29 September 2017

Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport

1 reference

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29 September 2017

Apolipoprotein E, amyloid, and Alzheimer disease

1 reference

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29 September 2017

Niemann-Pick Type C disease and Alzheimer's disease: the APP-endosome connection fattens up.

1 reference

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29 September 2017

The endocrine regulation of aging by insulin-like signals

1 reference

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29 September 2017

Cholesterol trafficking in the secretory and endocytic systems

1 reference

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29 September 2017

The Niemann-Pick C proteins and trafficking of cholesterol through the late endosomal/lysosomal system

1 reference

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29 September 2017

LRP: a multifunctional scavenger and signaling receptor

1 reference

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29 September 2017

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

1 reference

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29 September 2017

Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans.

1 reference

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29 September 2017

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630970

29 September 2017

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1 reference

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29 September 2017

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

1 reference

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29 September 2017

The neuropathological changes associated with normal brain aging

1 reference

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29 September 2017

Paired helical filament tau (PHFtau) in Niemann-Pick type C disease is similar to PHFtau in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630970

29 September 2017

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

1 reference

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29 September 2017

Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)

1 reference

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29 September 2017

Neuronal membrane cholesterol loss enhances amyloid peptide generation

1 reference

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27 June 2018

Distinct patterns of neuronal loss and Alzheimer's disease lesion distribution in elderly individuals older than 90 years.

1 reference

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27 June 2018

Genetic associations with human longevity at the APOE and ACE loci

1 reference

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27 June 2018

Polish Centenarians Programme. Multidisciplinary studies of successful ageing: aims, methods, and preliminary results.

1 reference

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4 September 2018

Association study of cholesterol-related genes in Alzheimer's disease.

1 reference

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4 September 2018

Targeting the role of the endosome in the pathophysiology of Alzheimer's disease: a strategy for treatment.

1 reference

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4 September 2018

Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling.

1 reference

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4 September 2018

Argyrophilic grain disease: frequency and neuropathology in centenarians.

1 reference

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4 September 2018

Cholesterol substrate pools and steroid hormone levels are normal in the face of mutational inactivation of NPC1 protein

1 reference

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4 September 2018

Sirtuin 1 (SIRT1) sequence variation is not associated with exceptional human longevity

1 reference

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4 September 2018

Neurodegeneration in heterozygous Niemann-Pick type C1 (NPC1) mouse: implication of heterozygous NPC1 mutations being a risk for tauopathy

1 reference

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4 September 2018

Liver disease with altered bile acid transport in Niemann-Pick C mice on a high-fat, 1% cholesterol diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630970

4 September 2018

NCR-1 and NCR-2, the C. elegans homologs of the human Niemann-Pick type C1 disease protein, function upstream of DAF-9 in the dauer formation pathways

1 reference

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4 September 2018

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

1 reference

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4 September 2018

Cholesterol storage and tau pathology in Niemann–Pick type C disease in the brain

1 reference

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4 September 2018

Sterols and intracellular vesicular trafficking: lessons from the study of NPC1.

1 reference

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4 September 2018

Distinguishing between neurodegenerative disease and disease-free aging: correlating neuropsychological evaluations and neuropathological studies in centenarians.

1 reference

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4 September 2018

DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity

1 reference

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4 September 2018

CNS synaptogenesis promoted by glia-derived cholesterol

1 reference

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4 September 2018

Mild amyloid pathology in the primary visual system of nonagenarians and centenarians.

1 reference

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4 September 2018

Clinical validity of Braak neuropathological staging in the oldest-old

1 reference

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4 September 2018

A model for niemann-pick type C disease in the nematode Caenorhabditis elegans

1 reference

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4 September 2018

The extent of neurofibrillary pathology in perforant pathway neurons is the key determinant of dementia in the very old

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18834923

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A novel PCR-RFLP assay for the detection of the single nucleotide polymorphism at position +1440 in the human CXCR2 gene

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18834923

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18834923

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1 reference

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Identifiers

10.1016/J.NEULET.2008.09.046

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

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