(Q37073009)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

title

A role for FOXO1 in BCR-ABL1-independent tyrosine kinase inhibitor resistance in chronic myeloid leukemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

main subject

chronic myeloid leukemia

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Matthew J Wongchenko

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Mark R. Lackner

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

author name string

M Wagle

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

S Lu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Y Guan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Y Wang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

L Amler

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

G Hampton

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

M W Deininger

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

T O'Hare

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Y Yan

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

publication date

8 March 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

issue

7

1 reference

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31 March 2020

page(s)

1493-1501

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

31 March 2020

copyright license

start time

8 March 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/leu.2016.51

0 references

cites work

A therapeutically targetable mechanism of BCR-ABL-independent imatinib resistance in chronic myeloid leukemia.

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Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia

29 September 2017

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The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factors

29 September 2017

1 reference

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29 September 2017

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29 September 2017

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Blockade of JAK2-mediated extrinsic survival signals restores sensitivity of CML cells to ABL inhibitors.

29 September 2017

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The Role of BCL2 Family of Apoptosis Regulator Proteins in Acute and Chronic Leukemias

29 September 2017

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FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

29 September 2017

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BCR-ABL1-independent PI3Kinase activation causing imatinib-resistance

29 September 2017

1 reference

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Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer

29 September 2017

1 reference

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TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

29 September 2017

1 reference

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Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

29 September 2017

1 reference

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BCR-ABL gene expression is required for its mutations in a novel KCL-22 cell culture model for acquired resistance of chronic myelogenous leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935980

AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance

29 September 2017

1 reference

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Efficacy of imatinib dose escalation in patients with chronic myeloid leukemia in chronic phase

29 September 2017

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The forkhead transcription factor FOXO3a increases phosphoinositide-3 kinase/Akt activity in drug-resistant leukemic cells through induction of PIK3CA expression

29 September 2017

1 reference

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Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines

29 September 2017

1 reference

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The involvement of FOXO1 in cytotoxic stress and drug-resistance induced by paclitaxel in ovarian cancers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935980

Multiple roles of FOXO transcription factors in mammalian cells point to multiple roles in cancer

29 September 2017

1 reference

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Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty

29 September 2017

1 reference

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Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy

29 September 2017

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BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia

29 September 2017

1 reference

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27 June 2018

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Contribution of BCR-ABL-independent activation of ERK1/2 to acquired imatinib resistance in K562 chronic myeloid leukemia cells

4 September 2018

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Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development

4 September 2018

1 reference

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4 September 2018

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20 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FLEU.2016.51

21 January 2018

Identifiers

DOI

10.1038/LEU.2016.51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044711%20AND%20SRC:MED&resulttype=core&format=json