(Q37073034)

English

Arabidopsis thaliana extracts optimized for polyphenols production as potential therapeutics for the APOE-modulated neuroinflammation characteristic of Alzheimer's disease in vitro

scientific article published on 07 July 2016

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scholarly article

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Europe PubMed Central

PMC publication ID

18 August 2017

Arabidopsis thaliana extracts optimized for polyphenols production as potential therapeutics for the APOE-modulated neuroinflammation characteristic of Alzheimer's disease in vitro (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Alzheimer's disease

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Arabidopsis thaliana

1 reference

0 references

1 reference

based on heuristic

inferred from title

2-[3-(4-Hydroxy-3,5-dimethoxyphenyl)prop-2-enoyloxy]butanedioic acid

1 reference

3-(4-hydroxy-3,5-dimethoxyphenyl)-N-[4-[3-[3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoylamino]propylamino]butyl]prop-2-enamide

1 reference

[4,5-Dihydroxy-2-[3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyloxy]-6-(hydroxymethyl)oxan-3-yl] 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate

1 reference

1 reference

author name string

Shivesh Ghura

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Leon Tai

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Ming Zhao

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Nicole Collins

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Chun-Tao Che

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Katherine M Warpeha

6

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Europe PubMed Central

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18 August 2017

Mary Jo LaDu

7

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Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

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publication date

7 July 2016

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Europe PubMed Central

PMC publication ID

18 August 2017

Scientific Reports

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Europe PubMed Central

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18 August 2017

6

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Europe PubMed Central

PMC publication ID

18 August 2017

1

1 reference

http://api.crossref.org/works/10.1038%2Fsrep29364

29364

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Europe PubMed Central

PMC publication ID

18 August 2017

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Creative Commons Attribution 4.0 International

7 July 2016

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April 2022 Public Data File from Crossref

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19 March 2024

https://api.unpaywall.org/v2/10.1038/srep29364?email=unpaywall_01@example.com

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based on heuristic

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Resveratrol as a Potential Therapeutic Candidate for the Treatment and Management of Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

29 September 2017

Bioavailability of dietary polyphenols: Factors contributing to their clinical application in CNS diseases

1 reference

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29 September 2017

Neuroinflammation in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

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APOE-modulated Aβ-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective

1 reference

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Anti-neuroinflammatory effects of DPTP, a novel synthetic clovamide derivative in in vitro and in vivo model of neuroinflammation.

1 reference

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Roles of resveratrol and other grape-derived polyphenols in Alzheimer's disease prevention and treatment

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Dietary polyphenols for treatment of Alzheimer's disease--future research and development

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Neuroprotective action of resveratrol

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Natural compounds and plant extracts as therapeutics against chronic inflammation in Alzheimer's disease--a translational perspective

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Mechanisms of action of phytochemicals from medicinal herbs in the treatment of Alzheimer's disease

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Follow-up evaluation of cognitive function in the randomized Alzheimer's Disease Anti-inflammatory Prevention Trial and its Follow-up Study

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Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition.

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Pirin1 (PRN1) is a multifunctional protein that regulates quercetin, and impacts specific light and UV responses in the seed-to-seedling transition of Arabidopsis thaliana

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Curcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st century

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ApoE4 delays dendritic spine formation during neuron development and accelerates loss of mature spines in vitro

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Inflammatory mediators as biomarkers in brain disorders

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Amyloid β-protein oligomers and Alzheimer's disease

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29 September 2017

Design, synthesis and biological evaluation of imine resveratrol derivatives as multi-targeted agents against Alzheimer's disease

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29 September 2017

The forgotten APOE allele: a review of the evidence and suggested mechanisms for the protective effect of APOE ɛ2.

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The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy

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Inflammatory process in Alzheimer's Disease

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Angiotensin converting enzyme inhibitors and the reduced risk of Alzheimer's disease in the absence of apolipoprotein E4 allele

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Down's syndrome, neuroinflammation, and Alzheimer neuropathogenesis

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29 September 2017

Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets.

1 reference

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29 September 2017

Results of a follow-up study to the randomized Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT).

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Flavonoids as antioxidants and developmental regulators: relative significance in plants and humans.

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Evidence for a protective effect of polyphenols-containing foods on cardiovascular health: an update for clinicians

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Neuroprotective and anti-inflammatory effects of the flavonoid-enriched fraction AF4 in a mouse model of hypoxic-ischemic brain injury

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Role of APOE and Age at Enrollment in the Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT).

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29 September 2017

Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects

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Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature

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Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis

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APOE genotype alters glial activation and loss of synaptic markers in mice

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Prevalence of apolipoprotein E4 genotype and homozygotes (APOE e4/4) among patients diagnosed with Alzheimer's disease: a systematic review and meta-analysis

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Neuroinflammation: modulation by flavonoids and mechanisms of action

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Alzheimer's disease, autoimmunity and inflammation. The good, the bad and the ugly

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Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease

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Extended results of the Alzheimer's disease anti-inflammatory prevention trial

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Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ)

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Effects of non-steroidal anti-inflammatory drug treatments on cognitive decline vary by phase of pre-clinical Alzheimer disease: findings from the randomized controlled Alzheimer's Disease Anti-inflammatory Prevention Trial

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Inhibitors of microglial neurotoxicity: focus on natural products

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Flavonoids as antioxidants evaluated by in vitro and in situ liver chemiluminescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

27 June 2018

Effects of flavonoids on nonenzymatic lipid peroxidation: Structure-activity relationship

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

27 June 2018

A comment on effect of plant extracts on Alzheimer's disease: An insight into therapeutic avenues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Reprogramming the phenylpropanoid metabolism in seeds of oilseed rape by suppressing the orthologs of reduced epidermal fluorescence1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Resveratrol protects cortical neurons against microglia-mediated neuroinflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

A review: inflammatory process in Alzheimer's disease, role of cytokines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

In vitro metabolism of nobiletin, a polymethoxy-flavonoid, by human liver microsomes and cytochrome P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Anti-inflammatory properties of clovamide and Theobroma cacao phenolic extracts in human monocytes: evaluation of respiratory burst, cytokine release, NF-κB activation, and PPARγ modulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Abeta1-42 oligomers and upregulating synaptic plasticity-related proteins in the hippocampus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

A novel polyamine acyltransferase responsible for the accumulation of spermidine conjugates in Arabidopsis seed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Adequate phenylalanine synthesis mediated by G protein is critical for protection from UV radiation damage in young etiolated Arabidopsis thaliana seedlings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Flavonoid intake and cognitive decline over a 10-year period.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Clovamide-type phenylpropenoic acid amides, N-coumaroyldopamine and N-caffeoyldopamine, inhibit platelet-leukocyte interactions via suppressing P-selectin expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Differential effects of oligomeric and fibrillar amyloid-beta 1-42 on astrocyte-mediated inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

A dual role for apolipoprotein e in neuroinflammation: anti- and pro-inflammatory activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Regulation of Flavonoid Biosynthetic Genes in Germinating Arabidopsis Seedlings.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Double placebo design in a prevention trial for Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Unique lipoproteins secreted by primary astrocytes from wild type, apoE (-/-), and human apoE transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Endogenous apolipoprotein E suppresses LPS-stimulated microglial nitric oxide production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4935988

4 September 2018

Apolipoprotein E receptors mediate the effects of beta-amyloid on astrocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/27383500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arabidopsis mutants lacking phenolic sunscreens exhibit enhanced ultraviolet-B injury and oxidative damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/27383500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors influencing the bioavailability of antioxidants in foods: A critical appraisal

1 reference

https://pubmed.ncbi.nlm.nih.gov/27383500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP29364

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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