(Q37079131)

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A novel dendritic cell targeting HPV16 E7 synthetic vaccine in combination with PD-L1 blockade elicits therapeutic antitumor immunity in mice.

scientific article published on 10 March 2016

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Europe PubMed Central

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20 March 2020

A novel dendritic cell targeting HPV16 E7 synthetic vaccine in combination with PD-L1 blockade elicits therapeutic antitumor immunity in mice (English)

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20 March 2020

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20 March 2020

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20 March 2020

author name string

Hang Zhou

2

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20 March 2020

Wenjun Wang

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20 March 2020

Mingzhao Zhu

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20 March 2020

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10 March 2016

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20 March 2020

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Europe PubMed Central

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20 March 2020

5

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20 March 2020

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20 March 2020

e1147641

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20 March 2020

Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b tri

1 reference

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Neoantigens in cancer immunotherapy.

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The future of immune checkpoint therapy

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PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma

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A novel method for synthetic vaccine construction based on protein assembly

1 reference

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Toll-like receptor agonist imiquimod facilitates antigen-specific CD8+ T-cell accumulation in the genital tract leading to tumor control through IFNγ

1 reference

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Anti-PD-1 antibody significantly increases therapeutic efficacy of Listeria monocytogenes (Lm)-LLO immunotherapy

1 reference

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29 September 2017

Preclinical evidence that PD1 blockade cooperates with cancer vaccine TEGVAX to elicit regression of established tumors

1 reference

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Targeting the tumor microenvironment with interferon-β bridges innate and adaptive immune responses.

1 reference

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29 September 2017

Dendritic-cell-based therapeutic cancer vaccines

1 reference

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Nivolumab plus ipilimumab in advanced melanoma

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Anti-programmed death-1 and anti-programmed death-ligand 1 antibodies in cancer therapy

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29 September 2017

Sortase-mediated modification of αDEC205 affords optimization of antigen presentation and immunization against a set of viral epitopes

1 reference

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Type I interferon response and innate immune sensing of cancer

1 reference

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29 September 2017

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

1 reference

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29 September 2017

PD-1/PD-L1 blockade can enhance HIV-1 Gag-specific T cell immunity elicited by dendritic cell-directed lentiviral vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938372

29 September 2017

Combining immunotherapy and targeted therapies in cancer treatment

1 reference

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29 September 2017

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

1 reference

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29 September 2017

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

1 reference

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29 September 2017

Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938372

29 September 2017

Immunosuppressive tumor microenvironment in cervical cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938372

29 September 2017

Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938372

29 September 2017

Control of cervicovaginal HPV-16 E7-expressing tumors by the combination of therapeutic HPV vaccination and vascular disrupting agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938372

29 September 2017

Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti–human DEC205 monoclonal antibody

1 reference

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29 September 2017

Human papillomavirus oncoproteins: pathways to transformation

1 reference

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Host immune responses to cervical cancer

1 reference

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The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

1 reference

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Human papillomavirus type 16 and 18 E7-pulsed dendritic cell vaccination of stage IB or IIA cervical cancer patients: a phase I escalating-dose trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938372

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Advances in dendritic-cell-based therapeutic vaccines for cervical cancer

1 reference

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Human papillomavirus infection: epidemiology and pathophysiology

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Recombinant Listeria vaccines containing PEST sequences are potent immune adjuvants for the tumor-associated antigen human papillomavirus-16 E7.

1 reference

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New tools for antigen delivery to the MHC class I pathway

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1 reference

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Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

1 reference

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Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple sclerosis

1 reference

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1 reference

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Identifiers

10.1080/2162402X.2016.1147641

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27471615%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27471615%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27471615%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

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