(Q37082758)

English

Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon

scientific article published on 09 September 2009

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1 reference

based on heuristic

inferred from title

multiple myeloma

1 reference

based on heuristic

inferred from title

10

object named as

Bart Barlogie

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Jeffrey R Sawyer

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Erming Tian

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Edward Thomas

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Mark Koller

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Colin Stangeby

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Gael Sammartino

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Linda Goosen

7

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Charles Swanson

8

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Regina L Binz

9

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

John Shaughnessy

11

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

0 references

publication date

9 September 2009

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

British Journal of Haematology

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

147

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

484-494

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Chromosome fragile sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Telomere-related genome instability in cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Gene amplification in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transpla

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Amplification and overexpression of CKS1B at chromosome band 1q21 is associated with reduced levels of p27Kip1 and an aggressive clinical course in multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Region-specific chromatin decondensation and micronucleus formation induced by 5-azacytidine in human TIG-7 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Chromosome organization and genic expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Induction of Tumors in Mice by Genomic Hypomethylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Initiation of the breakage-fusion-bridge mechanism through common fragile site activation in human breast cancer cells: the model of PIP gene duplication from a break at FRA7I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Molecular cytogenetic analysis of genomic instability at the 1q12-22 chromosomal site in B-cell non-Hodgkin lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Recent segmental duplications in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Uncovering novel inter- and intrachromosomal chromosome 1 aberrations in follicular lymphomas by using an innovative multicolor banding technique

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Myeloid cell factor-1 is a critical survival factor for multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Lessons from the human genome: transitions between euchromatin and heterochromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

JTB: a novel membrane protein gene at 1q21 rearranged in a jumping translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Induction of sister chromatid exchanges at common fragile sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Co-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

29 September 2017

Constitutive fragile sites and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

27 June 2018

A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

3 September 2018

The DNA demethylating 5-azaC induces endoreduplication in cultured Chinese hamster cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

3 September 2018

Genomic amplification of MET with boundaries within fragile site FRA7G and upregulation of MET pathways in esophageal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

3 September 2018

Prediction of Survival in Multiple Myeloma Based on Gene Expression Profiles Reveals Cell Cycle and Chromosomal Instability Signatures in High-Risk Patients and Hyperdiploid Signatures in Low-Risk Patients: A Study of the Intergroupe Francophone du M

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

4 December 2018

Molecular Dissection of Hyperdiploid Multiple Myeloma by Gene Expression Profiling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

4 December 2018

High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738438

4 December 2018

5-Azacytidine-induced undercondensations in human chromosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New classes of common fragile sites induced by 5-azacytidine and bromodeoxyuridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exclusion of specific human chromosomes into micronuclei by 5-azacytidine treatment of lymphocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytogenetic findings in 200 patients with multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Jumping translocations of chromosome 1q in multiple myeloma: evidence for a mechanism involving decondensation of pericentromeric heterochromatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of new nonrandom translocations in multiple myeloma with multicolor spectral karyotyping

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic instability in multiple myeloma: evidence for jumping segmental duplications of chromosome arm 1q

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significant increase of CKS1B amplification from monoclonal gammopathy of undetermined significance to multiple myeloma and plasma cell leukaemia as demonstrated by interphase fluorescence in situ hybridisation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple myeloma patients with CKS1B gene amplification have a shorter progression-free survival post-autologous stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional features of multiple myeloma patients with chromosome 1q gain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated soluble MUC1 levels and decreased anti-MUC1 antibody levels in patients with multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel evidence of a role for chromosome 1 pericentric heterochromatin in the pathogenesis of B-cell lymphoma and multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for common fragile site induction in amplification of human oncogenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2141.2009.07869.X

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q37082758&oldid=2158839994"