(Q37089549)

English

Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin

scientific article published on 24 June 2008

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin (English)

1 reference

Europe PubMed Central

18 August 2017

0 references

Dennis C. Liotta

11

object named as

Dennis Liotta

1 reference

Europe PubMed Central

18 August 2017

9

object named as

Aiming Sun

1 reference

Europe PubMed Central

18 August 2017

3

object named as

Shala L Thomas

1 reference

Europe PubMed Central

18 August 2017

author name string

Andrea L Kasinski

1

1 reference

Europe PubMed Central

18 August 2017

Yuhong Du

2

1 reference

Europe PubMed Central

18 August 2017

Jing Zhao

4

1 reference

Europe PubMed Central

18 August 2017

Shi-Yong Sun

5

1 reference

Europe PubMed Central

18 August 2017

Fadlo R Khuri

6

1 reference

Europe PubMed Central

18 August 2017

Cun-Yu Wang

7

1 reference

Europe PubMed Central

18 August 2017

Mamoru Shoji

8

1 reference

Europe PubMed Central

18 August 2017

James P Snyder

10

1 reference

Europe PubMed Central

18 August 2017

Haian Fu

12

1 reference

Europe PubMed Central

18 August 2017

publication date

24 June 2008

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Europe PubMed Central

18 August 2017

Molecular Pharmacology

1 reference

Europe PubMed Central

18 August 2017

74

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Europe PubMed Central

18 August 2017

3

1 reference

Europe PubMed Central

18 August 2017

654-661

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Europe PubMed Central

18 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2638506/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Bioavailability of curcumin: problems and promises

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638506

29 September 2017

EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638506

29 September 2017

Molecular targets of curcumin

1 reference

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29 September 2017

NMR study of the solution structure of curcumin

1 reference

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Biological effects of curcumin and its role in cancer chemoprevention and therapy

1 reference

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NF-kappaB and cancer: mechanisms and targets

1 reference

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29 September 2017

Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation

1 reference

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1 reference

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Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation

1 reference

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Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents

1 reference

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29 September 2017

Suppression of PTEN expression by NF-kappa B prevents apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638506

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Roscovitine and other purines as kinase inhibitors. From starfish oocytes to clinical trials

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Nf-kappa B, chemokine gene transcription and tumour growth

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Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions

1 reference

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A review of cancer chemopreventive agents

1 reference

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Aberrant rel/nfkb genes and activity in human cancer

1 reference

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Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638506

29 September 2017

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

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Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers

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IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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Cytotoxicity and cytoprotective activities of natural compounds. The case of curcumin.

1 reference

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Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638506

29 September 2017

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

1 reference

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Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines

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New colorimetric cytotoxicity assay for anticancer-drug screening

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EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism

1 reference

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Curcumin and derivatives

1 reference

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Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

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Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18577686

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Altered expression of the p50 subunit of the NF-kappa B transcription factor complex in non-small cell lung carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18577686

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inferred from PubMed ID database lookup

Antioxidative activity of tetrahydrocurcuminoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18577686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/MOL.108.046201

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

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