(Q37090907)

18 August 2017

Antithrombotic effects of synthetic peptides targeting various functional domains of thrombin (English)

1 reference

18 August 2017

5

L. A. Harker

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1385867

21 September 2022

4

S. R. Hanson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1385867

21 September 2022

1

A. B. Kelly

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1385867

21 September 2022

author name string

J. M. Maraganore

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1385867

21 September 2022

P. Bourdon

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1385867

21 September 2022

language of work or name

English

0 references

publication date

1 July 1992

1 reference

PMCID

49433

full work available at URL

18 August 2017

https://europepmc.org/articles/PMC49433

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1385867

https://europepmc.org/articles/PMC49433?pdf=render

21 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1385867

Proceedings of the National Academy of Sciences of the United States of America

21 September 2022

published in

1 reference

18 August 2017

89

1 reference

18 August 2017

13

1 reference

18 August 2017

6040-6044

1 reference

Anticoagulant activities of heparin oligosaccharides and their neutralization by platelet factor 4

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Fibrin monomer protects thrombin from inactivation by heparin-antithrombin III: implications for heparin efficacy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

A view of vascular stents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Agkistrodon piscivorus piscivorus platelet aggregation inhibitor: a potent inhibitor of platelet activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

The structure of a complex of recombinant hirudin and human alpha-thrombin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Inhibition of coagulation and thrombin-induced platelet activities by a synthetic dodecapeptide modeled on the carboxy-terminus of hirudin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Selective inhibition by a synthetic hirudin peptide of fibrin-dependent thrombosis in baboons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Hirudin interruption of heparin-resistant arterial thrombus formation in baboons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Structure of the hirugen and hirulog 1 complexes of alpha-thrombin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Experimental arterial thromboembolism in baboons. Mechanism, quantitation, and pharmacologic prevention

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

A catalytic role for heparin. Evidence for a ternary complex of heparin cofactor thrombin and heparin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Human alpha-thrombin binding to nonpolymerized fibrin-Sepharose: evidence for an anionic binding region

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Prevention of heparin-resistant thrombotic occlusion of hollow-fiber hemodialyzers by synthetic antithrombin

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

Domains specifying thrombin–receptor interaction

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

The COOH-terminal domain of hirudin. An exosite-directed competitive inhibitor of the action of alpha-thrombin on fibrinogen.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49433

The relation of platelet density to platelet age: survival of low- and high-density 111indium-labeled platelets in baboons

3 September 2018

1 reference

12 December 2020

Confluent durable endothelialization of endarterectomized baboon aorta by early attachment of cultured endothelial cells

1 reference

12 December 2020

Effects of thrombin inhibition on the development of acute platelet-thrombus deposition during angioplasty in pigs. Heparin versus recombinant hirudin, a specific thrombin inhibitor

1 reference

12 December 2020

Long-term follow-up after percutaneous transluminal coronary angioplasty. The early Zurich experience

1 reference

12 December 2020

Catalytic competence of human alpha- and gamma-thrombin in the activation of fibrinogen and factor XIII

1 reference

12 December 2020

Effect of heparin on the interaction between thrombin and hirudin

1 reference

12 December 2020

Kinetics of In-111-platelets in the baboon: I. Isolation and labelling of a viable and representative platelet population

1 reference

12 December 2020

Design and characterization of hirulogs: a novel class of bivalent peptide inhibitors of thrombin

1 reference

12 December 2020

Evaluation of the inhibition by heparin and hirudin of coagulation activation during r-tPA-induced thrombolysis

1 reference

12 December 2020

Discrimination between platelet-mediated and coagulation-mediated mechanisms in a model of complex thrombus formation in vivo

1 reference

12 December 2020

Anticoagulant activity of synthetic hirudin peptides

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.89.13.6040

1 reference

18 August 2017

0 references

1 reference

18 August 2017

1 reference

PMCID

49433