(Q37101353)

18 August 2017

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title

The effect of the microscopic and nanoscale structure on bone fragility (English)

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18 August 2017

M E Ruppel

1

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18 August 2017

L M Miller

series ordinal

2

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18 August 2017

D B Burr

series ordinal

3

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18 August 2017

language of work or name

English

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publication date

4 March 2008

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Osteoporosis International

18 August 2017

published in

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18 August 2017

volume

19

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18 August 2017

issue

9

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18 August 2017

page(s)

1251-1265

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https://scigraph.springernature.com/pub.10.1007/s00198-008-0579-1

18 August 2017

exact match

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cites work

Bone density and risk of hip fracture in men and women: cross sectional analysis

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In situ analysis of mineral content and crystallinity in bone using infrared micro-spectroscopy of the nu(4) PO(4)(3-) vibration.

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The association between environmental lead exposure and bone density in children

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Collagen cross-linking in human bone and articular cartilage. Age-related changes in the content of mature hydroxypyridinium residues

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Biochemical changes in the collagenous matrix of osteoporotic avian bone

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Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage

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Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications

21 January 2018

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Structural and functional changes of laminin and type IV collagen after nonenzymatic glycation

21 January 2018

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Effects of surface roughness and maximum load on the mechanical properties of cancellous bone measured by nanoindentation

21 January 2018

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Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis

21 January 2018

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12 December 2020

Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes

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12 December 2020

Strength of cancellous bone trabecular tissue from normal, ovariectomized and drug-treated rats over the course of ageing.

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12 December 2020

Comparison of histomorphometric descriptors of bone architecture with dual-energy X-ray absorptiometry for assessing bone loss in the orchidectomized rat.

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12 December 2020

High-resolution three-dimensional micro-computed tomography detects bone loss and changes in trabecular architecture early: comparison with DEXA and bone histomorphometry in a rat model of disuse osteoporosis.

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12 December 2020

Collagen cross-links in mineralizing tissues: a review of their chemistry, function, and clinical relevance

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12 December 2020

The thickness of human vertebral cortical bone and its changes in aging and osteoporosis: a histomorphometric analysis of the complete spinal column from thirty-seven autopsy specimens.

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12 December 2020

Brittle IV mouse model for osteogenesis imperfecta IV demonstrates postpubertal adaptations to improve whole bone strength

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12 December 2020

Relationships among carbonated apatite solubility, crystallite size, and microstrain parameters

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12 December 2020

Mechanical properties of human trabecular bone lamellae quantified by nanoindentation

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12 December 2020

The role of the collagen matrix in skeletal fragility

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12 December 2020

Role of advanced glycation end products (AGEs) and their receptor (RAGE) in the pathogenesis of diabetic microangiopathy

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12 December 2020

Collagen maturity, glycation induced-pentosidine, and mineralization are increased following 3-year treatment with incadronate in dogs

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12 December 2020

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12 December 2020

Fluoride salts are no better at preventing new vertebral fractures than calcium-vitamin D in postmenopausal osteoporosis: the FAVOStudy

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12 December 2020

Nanoindentation discriminates the elastic properties of individual human bone lamellae under dry and physiological conditions

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12 December 2020

Six-month daily administration of parathyroid hormone and parathyroid hormone-related protein peptides to adult ovariectomized rats markedly enhances bone mass and biomechanical properties: a comparison of human parathyroid hormone 1-34, parathyroid

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12 December 2020

Isolation of calcium-phosphate crystals of bone by non-aqueous methods at low temperature

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12 December 2020

Type I collagen mutation alters the strength and fatigue behavior of Mov13 cortical tissue

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12 December 2020

[The study on the anti-osteoporosis effect of clodronate in ovariectomized rats]

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12 December 2020

Effect of carbonate and fluoride on the dissolution behaviour of synthetic apatites

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12 December 2020

FTIR microspectroscopic analysis of normal human cortical and trabecular bone

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12 December 2020

Atomic force microscopy and nanoindentation characterization of human lamellar bone prepared by microtome sectioning and mechanical polishing technique.

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12 December 2020

Effects of vertebral bone fragility and bone formation rate on the mineralization levels of cancellous bone from white females

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12 December 2020

Cooperative deformation of mineral and collagen in bone at the nanoscale

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12 December 2020

Molecular changes in bone collagen in osteoporosis and osteoarthritis in the elderly

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12 December 2020

Effects of non-enzymatic glycation on cancellous bone fragility.

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12 December 2020

A proposed mechanism of the mitogenic action of fluoride on bone cells: inhibition of the activity of an osteoblastic acid phosphatase

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12 December 2020

Osteopontin Deficiency Increases Mineral Content and Mineral Crystallinity in Mouse Bone

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12 December 2020

The strength of a calcified tissue depends in part on the molecular structure and organization of its constituent mineral crystals in their organic matrix

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12 December 2020

Acid-stable fluorescent advanced glycation end products: vesperlysines A, B, and C are formed as crosslinked products in the Maillard reaction between lysine or proteins with glucose

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12 December 2020

The role of collagen in bone strength

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12 December 2020

Scanning acoustic microscope studies of the elastic properties of osteons and osteon lamellae

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12 December 2020

Collagen fiber orientation in the femoral necks of apes and humans: do their histological structures reflect differences in locomotor loading?

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12 December 2020

Mechanical behavior of damaged trabecular bone

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12 December 2020

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12 December 2020

Multinational, Placebo-Controlled, Randomized Trial of the Effects of Alendronate on Bone Density and Fracture Risk in Postmenopausal Women with Low Bone Mass: Results of the FOSIT Study

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12 December 2020

Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women

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12 December 2020

Role of nonenzymatic glycosylation of type I collagen in diabetic osteopenia

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12 December 2020

Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation

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12 December 2020

Suppression of pentosidine formation in galactosemic rat lens by an inhibitor of aldose reductase

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12 December 2020

Orientation of apatite in single osteon samples as studied by pole figures

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12 December 2020

Comparison of bone apatite in osteoporotic and normal Eskimos

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12 December 2020

The mechanical strength of bone in different rat models of experimental osteoporosis

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12 December 2020

Scanning Small Angle X-ray Scattering Analysis of Human Bone Sections

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12 December 2020

Nanoindentation and whole-bone bending estimates of material properties in bones from the senescence accelerated mouse SAMP6

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12 December 2020

Nonenzymatic glycosylation in vitro and in bovine endothelial cells alters basic fibroblast growth factor activity. A model for intracellular glycosylation in diabetes

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12 December 2020

Contribution of raloxifene and calcium and vitamin D3 supplementation to the increase of the degree of mineralization of bone in postmenopausal women

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12 December 2020

Therapeutic potential of breakers of advanced glycation end product–protein crosslinks

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12 December 2020

The elastic properties of trabecular and cortical bone tissues are similar: results from two microscopic measurement techniques

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12 December 2020

Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases

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12 December 2020

Scanning acoustic microscopy study of human cortical and trabecular bone

1 reference

12 December 2020

Femoral neck bone density. Direct measurement and histomorphometric validation

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12 December 2020

The role of collagen in the declining mechanical properties of aging human cortical bone

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12 December 2020

Does early PTH treatment compromise bone strength? The balance between remodeling, porosity, bone mineral, and bone size

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12 December 2020

Nanoscale Deformation Mechanisms in Bone

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12 December 2020

Collagen and bone strength

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12 December 2020

Effect of lead on parathyroid hormone-induced responses in rat osteoblastic osteosarcoma cells (ROS 17/2.8) using 19F-NMR.

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12 December 2020

Contribution of collagen and mineral to the elastic-plastic properties of bone

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12 December 2020

Aging of microstructural compartments in human compact bone

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12 December 2020

Accretion of bone quantity and quality in the developing mouse skeleton

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12 December 2020

Do more highly organized collagen fibrils increase bone mechanical strength in loss of mineral density after one-year running training?

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12 December 2020

Topographic imaging of mineral and collagen in the calcifying turkey tendon

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12 December 2020

Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group

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12 December 2020

Elastic properties of microstructural components of human bone tissue as measured by nanoindentation.

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12 December 2020

31P NMR and saturation transfer studies of the effect of Pb2+ on cultured osteoblastic bone cells

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12 December 2020

Structural and geometric changes in iliac bone: relationship to normal aging and osteoporosis

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12 December 2020

Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density

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12 December 2020

The effect of sodium fluoride on trabecular architecture

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12 December 2020

Chemical stability of carbonate- and fluoride-containing apatites

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12 December 2020

Fluoride for the treatment of postmenopausal osteoporotic fractures: a meta-analysis.

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12 December 2020

Consensus development conference: diagnosis, prophylaxis, and treatment of osteoporosis

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12 December 2020

The effect of risedronate on bone mineralization as measured by micro-computed tomography with synchrotron radiation: correlation to histomorphometric indices of turnover

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12 December 2020

Local variations in the micromechanical properties of mouse femur: the involvement of collagen fiber orientation and mineralization

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12 December 2020

Bone osteonal tissues by Raman spectral mapping: orientation-composition.

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12 December 2020

Bisphosphonates alter trabecular bone collagen cross-linking and isomerization in beagle dog vertebra.

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12 December 2020

Vertebral trabecular bone microscopic tissue elastic modulus and hardness do not change in ovariectomized rats

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12 December 2020

Advanced glycation end products and bone loss during aging.

1 reference

12 December 2020

Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis

1 reference

12 December 2020

Variations in the individual thick lamellar properties within osteons by nanoindentation

1 reference

12 December 2020

Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: relevance of glycated collagen products versus HbA1c as markers of diabetic complications. DCCT S

1 reference

12 December 2020

TEM analysis of the nanostructure of normal and osteoporotic human trabecular bone

1 reference

12 December 2020

Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen

1 reference

12 December 2020

Mechanical properties of adult vertebral cancellous bone: correlation with collagen intermolecular cross-links

1 reference

12 December 2020

Pathogenic effects of advanced glycosylation: biochemical, biologic, and clinical implications for diabetes and aging.

1 reference

12 December 2020

Nucleation and growth of mineral crystals in bone studied by small-angle X-ray scattering

1 reference

12 December 2020

A physical, chemical, and mechanical study of lumbar vertebrae from normal, ovariectomized, and nandrolone decanoate-treated cynomolgus monkeys (macaca fascicularis)

1 reference

12 December 2020

The relative effects of collagen fiber orientation, porosity, density, and mineralization on bone strength

1 reference

12 December 2020

Therapy for Fracture Prevention

1 reference

12 December 2020

Infrared microspectroscopic imaging of biomineralized tissues using a mercury-cadmium-telluride focal-plane array detector

1 reference

12 December 2020

Cellular lead toxicity and metabolism in primary and clonal osteoblastic bone cells

1 reference

12 December 2020

The role of fluoride in the prevention of osteoporosis

1 reference

12 December 2020

Bone crystal sizes: a comparison of transmission electron microscopic and X-ray diffraction line width broadening techniques

1 reference

12 December 2020

Structural alterations in rat skin and bone collagen fibrils induced by ovariectomy

1 reference

12 December 2020

Mechanical properties of collagen from decalcified rat femur in relation to age and in vitro maturation

1 reference

12 December 2020

Collagen cross-linking amino acids

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12 December 2020

1 reference

12 December 2020

Transitional structures in lamellar bone

1 reference

12 December 2020

Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae

1 reference

12 December 2020

Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study.

1 reference

12 December 2020

Microfocus small angle X-ray scattering reveals structural features in archaeological bone samples: detection of changes in bone mineral habit and size

1 reference

12 December 2020

Quantity and quality of trabecular bone in the femur are enhanced by a strongly anabolic, noninvasive mechanical intervention

1 reference

12 December 2020

Collagen fiber orientations in human secondary osteons

1 reference

12 December 2020

Assessing bone mineral density in vivo: dual energy X-ray absorptiometry

1 reference

12 December 2020

Osteonectin, a bone-specific protein linking mineral to collagen

1 reference

12 December 2020

Structure of the Femoral Neck in Hip Fracture: Cortical Bone Loss in the Inferoanterior to Superoposterior Axis

1 reference

12 December 2020

High-resolution AFM imaging of intact and fractured trabecular bone

1 reference

12 December 2020

Osteopenia induced by long-term, low- and high-level exposure of the adult rat to lead

1 reference

12 December 2020

Osteonectin, bone proteoglycan, and phosphophoryn defects in a form of bovine osteogenesis imperfecta

1 reference

12 December 2020

Bone matrix and mineral abnormalities in postmenopausal osteoporosis

1 reference

12 December 2020

Does the degree of laminarity correlate with site-specific differences in collagen fibre orientation in primary bone? An evaluation in the turkey ulna diaphysis

1 reference

12 December 2020

Relation of collagen fiber orientation to some mechanical properties of human cortical bone

1 reference

12 December 2020

The influence of bone volume fraction and ash fraction on bone strength and modulus

1 reference

12 December 2020

Strontium ranelate reduces the risk of vertebral and nonvertebral fractures in women eighty years of age and older

1 reference

12 December 2020

Advanced glycation end product modification of bone proteins and bone remodelling: hypothesis and preliminary immunohistochemical findings

1 reference

12 December 2020

Important determinants of bone strength: beyond bone mineral density

1 reference

12 December 2020

Alendronate influences bending force of femoral diaphysis after orchidectomy in rats.

1 reference

12 December 2020

The influence of collagen fiber orientation and other histocompositional characteristics on the mechanical properties of equine cortical bone

1 reference

12 December 2020

Scanning electron microscopy of lamellar bone

1 reference

12 December 2020

Treatment of postmenopausal vertebral osteopenia with monofluorophospate: a long-term calcium-controlled study

1 reference

12 December 2020

Constant mineralization density distribution in cancellous human bone

1 reference

12 December 2020

A three-dimensional simulation of age-related remodeling in trabecular bone

1 reference

12 December 2020

Effect of high-impact and low-repetition training on bones in ovariectomized rats

1 reference

12 December 2020

Osteoblasts and chondrocytes are important target cells for the toxic effects of lead

1 reference

12 December 2020

Post-translational modifications in the collagen of human osteoporotic femoral head

1 reference

12 December 2020

Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways.

1 reference

12 December 2020

FTIR microspectroscopic analysis of human osteonal bone

1 reference

12 December 2020

Contribution of collagen and mineral to the elastic anisotropy of bone

1 reference

12 December 2020

Osteonectin content in human osteogenesis imperfecta bone shows a range similar to that of two bovine models of OI

1 reference

12 December 2020

BAPN dose dependence of mature crosslinking in bone matrix collagen of rabbit compact bone: corresponding variation of sonic velocity and equatorial diffraction spacing

1 reference

12 December 2020

The influence of inflammation-mediated osteopenia (IMO) on the structure of rabbit bone and skin collagen fibrils

1 reference

12 December 2020

Size and shape of mineralites in young bovine bone measured by atomic force microscopy.

1 reference

12 December 2020

Toward a Maillard reaction theory of aging.

1 reference

12 December 2020

Influence of estrogen therapy at conventional and high doses on the degree of mineralization of iliac bone tissue: a quantitative microradiographic analysis in postmenopausal women

1 reference

12 December 2020

Effects of lead on osteoclast-like cell formation in mouse bone marrow cell cultures

1 reference

12 December 2020

Cross-linking and new bone collagen synthesis in immobilized and recovering primate osteoporosis

1 reference

12 December 2020

Effect of lead on bone development and bone mass: a morphometric, densitometric, and histomorphometric study in growing rats

1 reference

12 December 2020

Bone mineralization density and femoral neck fragility

1 reference

12 December 2020

Basement-membrane stromal relationships: interactions between collagen fibrils and the lamina densa

1 reference

12 December 2020

Influence of nutritional factors on bone collagen fibrils in ovariectomized rats

1 reference

12 December 2020

Reduced concentrations of collagen cross-links are associated with reduced strength of bone.

1 reference

12 December 2020

Crystal-collagen relationships in calcified turkey leg tendons visualized by selected-area dark field electron microscopy

1 reference

12 December 2020

Advanced glycation end products (AGEs) and diabetic vascular complications

1 reference

12 December 2020

Ten year probabilities of osteoporotic fractures according to BMD and diagnostic thresholds

1 reference

12 December 2020

Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial

1 reference

12 December 2020

Mineral anisotropy in mineralized tissues is similar among species and mineral growth occurs independently of collagen orientation in rats: results from acoustic velocity measurements

1 reference

12 December 2020

Characterization of bone mineral crystals in horse radius by small-angle X-ray scattering

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12 December 2020

1 reference

12 December 2020

Trabecular microfracture and the influence of pyridinium and non-enzymatic glycation-mediated collagen cross-links

1 reference

12 December 2020

Mineralized collagen fibrils: a mechanical model with a staggered arrangement of mineral particles

1 reference

12 December 2020

The elastic modulus for bone

1 reference

12 December 2020

Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin

1 reference

12 December 2020

The effects of inflammation-mediated osteoporosis (IMO) on the skeletal Ca/P ratio and on the structure of rabbit bone and skin collagen

1 reference

12 December 2020

The TEM characterization of the lamellar structure of osteoporotic human trabecular bone

1 reference

12 December 2020

Extracellular post-translational modifications of collagen are major determinants of biomechanical properties of fetal bovine cortical bone

1 reference

12 December 2020

Alendronate increases degree and uniformity of mineralization in cancellous bone and decreases the porosity in cortical bone of osteoporotic women

1 reference

12 December 2020

Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss

1 reference

12 December 2020

Comparison of mineral quality and quantity in iliac crest biopsies from high- and low-turnover osteoporosis: an FT-IR microspectroscopic investigation.

1 reference

12 December 2020

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

1 reference

12 December 2020

The loci of mineral in turkey leg tendon as seen by atomic force microscope and electron microscopy

1 reference

12 December 2020

The burden of rheumatoid arthritis: facts and figures.

1 reference

12 December 2020

Structural relations between collagen and mineral in bone as determined by high voltage electron microscopic tomography

1 reference

12 December 2020

Mechanisms of maturation and ageing of collagen

1 reference

12 December 2020

Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues.

1 reference

12 December 2020

Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group

1 reference

12 December 2020

The effects of collagen fiber orientation, porosity, density, and mineralization on bovine cortical bone bending properties

1 reference

12 December 2020

Twisted plywood architecture of collagen fibrils in human compact bone osteons

1 reference

12 December 2020

Intervention against the Maillard reaction in vivo

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12 December 2020

A scanning electron microscope study of human bony lamellae. Proposal for a new model of collagen lamellar organization

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12 December 2020

1 reference

12 December 2020

A damage model for nonlinear tensile behavior of cortical bone

1 reference

12 December 2020

Effect of sodium fluoride, calcium, phosphate, and vitamin D2 on trabecular bone balance and remodeling in osteoporotics

1 reference

12 December 2020

Fracture incidence and association with bone mineral density in elderly men and women: the Rotterdam Study

1 reference

12 December 2020

Bone fragility and collagen cross-links.

1 reference

12 December 2020

The effects of ageing and changes in mineral content in degrading the toughness of human femora

1 reference

12 December 2020

Role of collagen and other organics in the mechanical properties of bone

1 reference

12 December 2020

The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates

1 reference

12 December 2020

A comparison of different screening strategies to identify elderly women at high risk of hip fracture: results from the EPIDOS prospective study.

1 reference

12 December 2020

Shape and size of isolated bone mineralites measured using atomic force microscopy

1 reference

12 December 2020

The long-term effect of ovariectomy on the quality and quantity of cancellous bone in young macaques

1 reference

12 December 2020

Materials become insensitive to flaws at nanoscale: lessons from nature

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12 December 2020

Increased bone formation in osteocalcin-deficient mice.

1 reference

12 December 2020

Complementary information on bone ultrastructure from scanning small angle X-ray scattering and Fourier-transform infrared microspectroscopy

1 reference

12 December 2020

Reduced concentration of collagen reducible cross links in human trabecular bone with respect to age and osteoporosis.

1 reference

12 December 2020

Age and bone mass as predictors of fracture in a prospective study

1 reference

12 December 2020

Fourier transform infrared spectroscopy of the solution-mediated conversion of amorphous calcium phosphate to hydroxyapatite: new correlations between X-ray diffraction and infrared data

1 reference

12 December 2020

The morphology of bone mineral crystals.

1 reference

12 December 2020

Crystal size and organization in bone

1 reference

12 December 2020

Abnormal bone mineralization after fluoride treatment in osteoporosis: A small-angle x-ray-scattering study

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12 December 2020

Aging and cross-linking of skin collagen

1 reference

12 December 2020

10.1007/S00198-008-0579-1

Identifiers

DOI

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18 August 2017

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