(Q37103177)

18 August 2017

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title

S100A4: a common mediator of epithelial-mesenchymal transition, fibrosis and regeneration in diseases? (English)

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18 August 2017

2

Jakob L Hansen

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author name string

Mikael Schneider

series ordinal

1

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18 August 2017

Jakob L Hansen

series ordinal

2

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18 August 2017

Søren P Sheikh

series ordinal

3

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18 August 2017

publication date

6 March 2008

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Journal of Molecular Medicine

18 August 2017

published in

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18 August 2017

volume

86

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18 August 2017

issue

5

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18 August 2017

page(s)

507-522

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

18 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00109-007-0301-3

S100A4/Mts1 produces murine pulmonary artery changes resembling plexogenic arteriopathy and is increased in human plexogenic arteriopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-007-0301-3

Extracellular S100A4 stimulates the migration rate of astrocytic tumor cells by modifying the organization of their actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-007-0301-3

Immunocytochemical distribution of the calcium-binding protein p9Ka in normal rat tissues: variation in the cellular location in different tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-007-0301-3

Metastasis-associated protein S100A4: spotlight on its role in cell migration

21 January 2018

1 reference

12 December 2020

Isoproterenol-induced myocardial injury resulting in altered S100A4 and S100A11 protein expression in the rat.

1 reference

12 December 2020

S100A4 is upregulated in injured myocardium and promotes growth and survival of cardiac myocytes

1 reference

12 December 2020

Wnt/beta-catenin signaling in cancer stemness and malignant behavior

1 reference

12 December 2020

Differentiation and migration of astrocytes in the spinal cord following dorsal root injury in the adult rat.

1 reference

12 December 2020

The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer

1 reference

12 December 2020

Expression of the rat, S-100-related, calcium-binding protein gene, p9Ka, in transgenic mice demonstrates different patterns of expression between these two species

1 reference

12 December 2020

Metastasis-associated protein S100A4--a potential prognostic marker for colorectal cancer

1 reference

12 December 2020

Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization.

1 reference

12 December 2020

Expression of S100A4 by a variety of cell types present in the tumor microenvironment of human breast cancer

1 reference

12 December 2020

Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor

1 reference

12 December 2020

Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction

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12 December 2020

Intimal smooth muscle cells of porcine and human coronary artery express S100A4, a marker of the rhomboid phenotype in vitro.

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12 December 2020

Metastasis-associated protein S100A4 induces angiogenesis through interaction with Annexin II and accelerated plasmin formation

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12 December 2020

Expression of the calcium-binding protein S100A4 is markedly up-regulated by osmotic stress and is involved in the renal osmoadaptive response

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12 December 2020

S100A4 is expressed at site of invasion in rheumatoid arthritis synovium and modulates production of matrix metalloproteinases.

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12 December 2020

Identification of a core set of genes that signifies pathways underlying cardiac hypertrophy

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12 December 2020

Prognostic significance of S100A4 expression in gallbladder cancer

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12 December 2020

Expression of antisense RNA to S100A4 gene encoding an S100-related calcium-binding protein suppresses metastatic potential of high-metastatic Lewis lung carcinoma cells

1 reference

12 December 2020

Mutually antagonistic actions of S100A4 and S100A1 on normal and metastatic phenotypes

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12 December 2020

Molecular mechanisms of Ca(2+) signaling in neurons induced by the S100A4 protein

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12 December 2020

Metastasis-associated protein Mts1 (S100A4) inhibits CK2-mediated phosphorylation and self-assembly of the heavy chain of nonmuscle myosin

1 reference

12 December 2020

Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours

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12 December 2020

Oligomeric forms of the metastasis-related Mts1 (S100A4) protein stimulate neuronal differentiation in cultures of rat hippocampal neurons

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12 December 2020

Friends or foes - bipolar effects of the tumour stroma in cancer

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12 December 2020

A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration.

1 reference

12 December 2020

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

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12 December 2020

Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury

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12 December 2020

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

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12 December 2020

Identification and characterization of a fibroblast marker: FSP1

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12 December 2020

Characterization of fibroblast-specific protein 1 in pulmonary fibrosis

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12 December 2020

Expression of S100A4 and Met: potential predictors for metastasis and survival in early-stage breast cancer.

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12 December 2020

Distinct subcellular localization of calcium binding S100 proteins in human smooth muscle cells and their relocation in response to rises in intracellular calcium

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12 December 2020

Metastasis of mammary carcinomas in GRS/A hybrid mice transgenic for the mts1 gene

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12 December 2020

Clinical significance of S100A4 and E-cadherin-related adhesion molecules in non-small cell lung cancer

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12 December 2020

Prognostic significance of calcium-binding protein S100A4 in colorectal cancer

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12 December 2020

Expression of the metastasis-associated mts1 gene during mouse development.

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12 December 2020

Extracellular S100A4(mts1) stimulates invasive growth of mouse endothelial cells and modulates MMP-13 matrix metalloproteinase activity

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12 December 2020

Differential expression of S100A2 and S100A4 during progression of human prostate adenocarcinoma

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12 December 2020

Mts1 regulates the assembly of nonmuscle myosin-IIA

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12 December 2020

Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products.

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12 December 2020

Overexpression of S100A4 is closely related to the aggressiveness of gastric cancer

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12 December 2020

Interdependent serotonin transporter and receptor pathways regulate S100A4/Mts1, a gene associated with pulmonary vascular disease

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12 December 2020

Modulation of mts1 expression in mouse and human normal and tumor cells

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12 December 2020

Phenotype of airway epithelial cells suggests epithelial to mesenchymal cell transition in clinically stable lung transplant recipients.

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12 December 2020

Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts

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12 December 2020

Transforming growth factor beta in cardiovascular development and function

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12 December 2020

Modified expression of Mts1/S100A4 protein in C6 glioma cells or surrounding astrocytes affects migration of tumor cells in vitro and in vivo.

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12 December 2020

Renewal of FSP1: a marker of fibrogenesis on human renal biopsies

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12 December 2020

Up-regulation of metastasis-promoting S100A4 (Mts-1) in rheumatoid arthritis: putative involvement in the pathogenesis of rheumatoid arthritis

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12 December 2020

Increased S100A4 expression combined with decreased E-cadherin expression predicts a poor outcome of patients with pancreatic cancer

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12 December 2020

Early role of Fsp1 in epithelial-mesenchymal transformation

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12 December 2020

Sensory neurite outgrowth on white matter astrocytes is influenced by intracellular and extracellular S100A4 protein

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12 December 2020

S100A4 (Mts1): is there any relation to the pathogenesis of rheumatoid arthritis?

1 reference

12 December 2020

Immunofluorometric assay for the metastasis-related protein S100A4: release of S100A4 from normal blood cells prohibits the use of S100A4 as a tumor marker in plasma and serum

1 reference

12 December 2020

Metastasis-associated mts1 (S100A4) protein is selectively expressed in white matter astrocytes and is up-regulated after peripheral nerve or dorsal root injury

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12 December 2020

Expression of S100A4 protein is associated with metastasis and reduced survival in human bladder cancer

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12 December 2020

Delayed inflammation-associated corneal neovascularization in MMP-2-deficient mice.

1 reference

12 December 2020

Biliary epithelial-mesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis

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12 December 2020

Comparison of the metastasis-inducing protein S100A4 (p9ka) with other prognostic markers in human breast cancer

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12 December 2020

The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor

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12 December 2020

Association of S100A4 and osteopontin with specific prognostic factors and survival of patients with minimally invasive breast cancer

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12 December 2020

Nuclear expression of S100A4 is associated with aggressive behavior of epithelial ovarian carcinoma: an important autocrine/paracrine factor in tumor progression

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12 December 2020

Mts1/S100A4 stimulates human pulmonary artery smooth muscle cell migration through multiple signaling pathways

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12 December 2020

Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation

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12 December 2020

The microenvironment of the tumour-host interface

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12 December 2020

Calcium-binding protein S100A4 in health and disease

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12 December 2020

Tissue-specific posttranscriptional downregulation of expression of the S100A4(mts1) gene in transgenic animals

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12 December 2020

Heterocomplex formation between metastasis-related protein S100A4 (Mts1) and S100A1 as revealed by the yeast two-hybrid system

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12 December 2020

Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay

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12 December 2020

Protein S100A4: too long overlooked by pathologists?

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12 December 2020

Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition.

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12 December 2020

Relevance of the stroma and epithelial-mesenchymal transition (EMT) for the rheumatic diseases

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12 December 2020

Immunolocalization of fibroblast growth factor-1 (FGF-1), its receptor (FGFR-1), and fibroblast-specific protein-1 (FSP-1) in inflammatory renal disease

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12 December 2020

Parietal endoderm secreted S100A4 promotes early cardiomyogenesis in embryoid bodies.

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12 December 2020

Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys

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12 December 2020

Calcium-dependent and -independent interactions of the S100 protein family.

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12 December 2020

Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosis

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12 December 2020

Sensitization of interferon-gamma induced apoptosis in human osteosarcoma cells by extracellular S100A4

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12 December 2020

Differential expression of S100A2 and S100A4 in lung adenocarcinomas: clinicopathological significance, relationship to p53 and identification of their target genes

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12 December 2020

Antibodies against macrophages that overlap in specificity with fibroblasts.

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12 December 2020

Metastasis-associated S100A4 (Mts1) protein is expressed in subpopulations of sensory and autonomic neurons and in Schwann cells of the adult rat

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12 December 2020

Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmonary hypertension

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12 December 2020

Human S100A4 (p9Ka) induces the metastatic phenotype upon benign tumour cells

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12 December 2020

Mts1 protein expression in the central nervous system after injury.

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12 December 2020

A proximal activator of transcription in epithelial-mesenchymal transition

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12 December 2020

Extracellular role of S100A4 calcium-binding protein in the periodontal ligament

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12 December 2020

Expression profiling of laser-microdissected intrapulmonary arteries in hypoxia-induced pulmonary hypertension

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12 December 2020

Selective depletion of fibroblasts preserves morphology and the functional integrity of peritoneum in transgenic mice with peritoneal fibrosing syndrome

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12 December 2020

Poor outcome of patients with pulmonary adenocarcinoma showing decreased E-cadherin combined with increased S100A4 expression.

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12 December 2020

S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles

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12 December 2020

Inverse expression of S100A4 and E-cadherin is associated with metastatic potential in gastric cancer

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12 December 2020

Extracellular S100A1 protein inhibits apoptosis in ventricular cardiomyocytes via activation of the extracellular signal-regulated protein kinase 1/2 (ERK1/2)

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12 December 2020

Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka)

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12 December 2020

The Mts1/S100A4 protein is a neuroprotectant

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12 December 2020

Complex networks orchestrate epithelial-mesenchymal transitions

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12 December 2020

Reversal of the in vivo metastatic phenotype of human tumor cells by an anti-CAPL (mts1) ribozyme

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12 December 2020

Correlation of S100A4 expression with invasion and metastasis in oral squamous cell carcinoma

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12 December 2020

Regulation of myosin-IIA assembly and Mts1 binding by heavy chain phosphorylation

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12 December 2020

Effect of Mts1 on the structure and activity of nonmuscle myosin II

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12 December 2020

Intracellular calcium-binding protein S100A4 influences injury-induced migration of white matter astrocytes.

1 reference

12 December 2020

Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation.

1 reference

12 December 2020

Focal S100A4 protein expression is an independent predictor of development of metastatic disease in cystectomized bladder cancer patients

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12 December 2020

The metastasis associated protein S100A4: role in tumour progression and metastasis

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12 December 2020

Calvasculin, an encoded protein from mRNA termed pEL-98, 18A2, 42A, or p9Ka, is secreted by smooth muscle cells in culture and exhibits Ca(2+)-dependent binding to 36-kDa microfibril-associated glycoprotein

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12 December 2020

Increased expression of S100A4 and its prognostic significance in esophageal squamous cell carcinoma

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12 December 2020

Nuclear localization of the metastasis-related protein S100A4 correlates with tumour stage in colorectal cancer

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12 December 2020

Calcyclin and calvasculin exist in human platelets

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12 December 2020

Parietal endoderm secreted SPARC promotes early cardiomyogenesis in vitro

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12 December 2020

Mass spectrometric proteomics profiles of in vivo tumor secretomes: capillary ultrafiltration sampling of regressive tumor masses

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12 December 2020

Prognostic significance of the metastasis-inducing protein S100A4 (p9Ka) in human breast cancer

1 reference

12 December 2020

Effect of mts1 (S100A4) expression on the progression of human breast cancer cells

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12 December 2020

Epithelial to mesenchymal transition during late deterioration of human kidney transplants: the role of tubular cells in fibrogenesis

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12 December 2020

S100A4, a mediator of metastasis

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12 December 2020

Proteome profiling of corneal epithelium and identification of marker proteins for keratoconus, a pilot study

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12 December 2020

Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1).

1 reference

12 December 2020

Metastasis-associated Mts1 (S100A4) Protein Modulates Protein Kinase C Phosphorylation of the Heavy Chain of Nonmuscle Myosin

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12 December 2020

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins

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12 December 2020

Fibroblast-specific protein 1 is a specific prognostic marker for renal survival in patients with IgAN.

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12 December 2020

Involvement of S100A4 in Stromal Fibroblasts of the Regenerating Cornea

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12 December 2020

Progressive renal fibrosis in murine polycystic kidney disease: an immunohistochemical observation

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12 December 2020

BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

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12 December 2020

Interaction in vivo and in vitro of the metastasis-inducing S100 protein, S100A4 (p9Ka) with S100A1

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12 December 2020

10.1007/S00109-007-0301-3

Identifiers

DOI

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18 August 2017

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