(Q37112692)

18 August 2017

ADP-ribosylation of translation elongation factor 2 by diphtheria toxin in yeast inhibits translation and cell separation (English)

1 reference

18 August 2017

Maria K Mateyak

1

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Terri Goss Kinzy

object named as

Terri Goss Kinzy

series ordinal

2

0 references

language of work or name

English

0 references

publication date

12 July 2013

1 reference

Journal of Biological Chemistry

18 August 2017

1 reference

18 August 2017

288

1 reference

18 August 2017

34

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18 August 2017

24647-24655

1 reference

PMC publication ID

3750162

describes a project that uses

18 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3750162/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The amidation step of diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Cotranslational response to proteotoxic stress by elongation pausing of ribosomes

14 September 2017

1 reference

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Widespread regulation of translation by elongation pausing in heat shock

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Unraveling the dynamics of ribosome translocation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

The elongation, termination, and recycling phases of translation in eukaryotes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Morphogenesis and the cell cycle

14 September 2017

1 reference

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The power of MEN in cytokinesis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Fast-acting and nearly gratuitous induction of gene expression and protein depletion in Saccharomyces cerevisiae.

14 September 2017

1 reference

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Identification of an mRNP complex regulating tumorigenesis at the translational elongation step

14 September 2017

1 reference

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The eukaryotic translation elongation Factor 1Bgamma has a non-guanine nucleotide exchange factor role in protein metabolism

14 September 2017

1 reference

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Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins

14 September 2017

1 reference

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Cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae

14 September 2017

1 reference

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Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation

14 September 2017

1 reference

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Translation elongation factor 2 anticodon mimicry domain mutants affect fidelity and diphtheria toxin resistance

14 September 2017

1 reference

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Global translational responses to oxidative stress impact upon multiple levels of protein synthesis.

14 September 2017

1 reference

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Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Yeast as a sensor of factors affecting the accuracy of protein synthesis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Retroviral insertional mutagenesis identifies a small protein required for synthesis of diphthamide, the target of bacterial ADP-ribosylating toxins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Eng1p, an endo-1,3-beta-glucanase localized at the daughter side of the septum, is involved in cell separation in Saccharomyces cerevisiae.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Glucose depletion rapidly inhibits translation initiation in yeast

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Saccharomyces cerevisiae spheroplasts are sensitive to the action of diphtheria toxin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

In vitro biosynthesis of diphthamide, studied with mutant Chinese hamster ovary cells resistant to diphtheria toxin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Cellular ADP-ribosyltransferase with the same mechanism of action as diphtheria toxin and Pseudomonas toxin A

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Diphtheria toxin-resistant mutants of Saccharomyces cerevisiae

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Elevated recombination rates in transcriptionally active DNA

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Endogenous ADP-ribosylation of elongation factor 2 in polyoma virus-transformed baby hamster kidney cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Kinetic determination of the effects of ADP-ribosylation on the interaction of eukaryotic elongation factor 2 with ribosomes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Protein synthesis requirements for nuclear division, cytokinesis, and cell separation in Saccharomyces cerevisiae

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

DPH5, a methyltransferase gene required for diphthamide biosynthesis in Saccharomyces cerevisiae

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Effect of elongation factor 2 and of adenosine diphosphate-ribosylated elongation factor 2 on translocation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Eukaryotic polyribosome profile analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Saccharomyces cerevisiae elongation factor 2. Mutagenesis of the histidine precursor of diphthamide yields a functional protein that is resistant to diphtheria toxin.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Mutations in the elongation factor 2 gene which confer resistance to diphtheria toxin and Pseudomonas exotoxin A. Genetic and biochemical analyses

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Interaction of ADP-ribosylated aminoacyl-transferase II with GTP and with ribosomes.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Crystal structure of ADP-ribosylated ribosomal translocase from Saccharomyces cerevisiae

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Purification and crystallization of the yeast elongation factor eEF2.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750162

Elongation factor 2 mutants deficient in diphthamide formation show temperature-sensitive cell growth

3 September 2018

1 reference

12 December 2020

Elongation factor 2 as a novel target for selective inhibition of fungal protein synthesis

1 reference

12 December 2020

Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin

1 reference

12 December 2020

Formation of a complex involving ADP-ribosylated human translocation factor, guanosine nucleotide and ribosomes

1 reference

12 December 2020

Interactions of adenosine diphosphate-ribosylated elongation factor 2 with ribosomes

1 reference

12 December 2020

One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell

1 reference

12 December 2020

Biosynthetic labeling of diphthamide in Saccharomyces cerevisiae

1 reference

12 December 2020

Nucleotide binding to elongation factor 2 inactivated by diphtheria toxin

1 reference

12 December 2020

Heterogeneity of native rat liver elongation factor 2

1 reference

12 December 2020

ADP-ribosylated elongation factor 2 (ADP-ribosyl-EF-2) is unable to promote translocation within the ribosome

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M113.488783

1 reference

18 August 2017

1 reference

PMC publication ID

3750162

18 August 2017

PubMed publication ID

23853096

1 reference

PMC publication ID

3750162