(Q37120884)

18 August 2017

Common variation in the NOS1AP gene is associated with drug-induced QT prolongation and ventricular arrhythmia (English)

1 reference

18 August 2017

Rachel Bastiaenen

6

0 references

Yalda Jamshidi

Yalda Jamshidi

1

0 references

Toby Johnson

Toby Johnson

5

0 references

Elijah Behr

Elijah R Behr

19

0 references

Chrysoula Dalageorgou

3

Chrysoula Dalageorgou

1 reference

18 August 2017

15

Patricia B Munroe

1 reference

18 August 2017

13

Saad Shakir

0 references

A. John Camm

16

A John Camm

1 reference

18 August 2017

10

Harold Snieder

1 reference

18 August 2017

18

Dan M Roden

1 reference

18 August 2017

Ilja M Nolte

2

1 reference

18 August 2017

Dongling Zheng

4

1 reference

18 August 2017

Suzanne Ruddy

7

1 reference

18 August 2017

Daniel Talbott

8

1 reference

18 August 2017

Kris J Norris

9

1 reference

18 August 2017

Alfred L George

11

1 reference

18 August 2017

Vanessa Marshall

12

1 reference

18 August 2017

Saad Shakir

13

1 reference

18 August 2017

Prince J Kannankeril

14

1 reference

18 August 2017

Steve Jeffery

17

1 reference

18 August 2017

language of work or name

English

0 references

publication date

6 June 2012

1 reference

Journal of the American College of Cardiology

18 August 2017

1 reference

18 August 2017

60

1 reference

18 August 2017

9

1 reference

18 August 2017

841-850

1 reference

Factors affecting the degree of QT prolongation with drug challenge in a large cohort of normal volunteers

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Rhythm control agents and adverse events in patients with atrial fibrillation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

NOS1AP is a genetic modifier of the long-QT syndrome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Common variants at ten loci influence QT interval duration in the QTGEN Study

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Calcium channel blockers, NOS1AP, and heart-rate-corrected QT prolongation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Association of NOS1AP genetic variants with QT interval duration in families from the Diabetes Heart Study

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

A second generation human haplotype map of over 3.1 million SNPs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

PLINK: a tool set for whole-genome association and population-based linkage analyses

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac repolarization in the old order Amish

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Neuronal nitric oxide synthase signaling in the heart is regulated by the sarcolemmal calcium pump 4b

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Torsade de pointes induced by short-term oral amiodarone therapy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Long QT syndrome: reduced repolarization reserve and the genetic link

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Drug-induced prolongation of the QT interval

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Genome-wide mapping of human loci for essential hypertension

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Evolution, mechanisms, and classification of antiarrhythmic drugs: focus on class III actions

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Channel specificity in antiarrhythmic drug action. Mechanism of potassium channel block and its role in suppressing and aggravating cardiac arrhythmias

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Common NOS1AP variants are associated with a prolonged QTc interval in the Rotterdam Study

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Amiodarone blocks inactivated cardiac sodium channels

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Barium-induced nondriven action potentials as a model of triggered potentials from early afterdepolarizations: significance of slow channel activity and differing effects of quinidine and amiodarone

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Polymorphisms in the NOS1AP gene modulate QT interval duration and risk of arrhythmias in the long QT syndrome.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Identification of a common variant at the NOS1AP locus strongly associated to QT-interval duration.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Common variation in NOS1AP and KCNH2 genes and QT interval duration in young adults. The Cardiovascular Risk in Young Finns Study

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Amiodarone and N-desethylamiodarone enhance endothelial nitric oxide production in human endothelial cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac repolarization in 3761 individuals from two independent populations

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753216

The adrenergic antagonism of amiodarone

4 December 2018

1 reference

12 December 2020

Cardiac β-adrenoceptor modulation by amiodarone

1 reference

12 December 2020

Frequency-dependent effects of amiodarone on atrioventricular nodal function and slow-channel action potentials: evidence for calcium channel-blocking activity

1 reference

12 December 2020

1 reference

12 December 2020

Effects of amiodarone on beating rate and Na-K-ATPase activity in cultured neonatal rat heart myocytes

1 reference

12 December 2020

Conditional neuronal nitric oxide synthase overexpression impairs myocardial contractility

1 reference

12 December 2020

10.1016/J.JACC.2012.03.031

Identifiers

DOI

1 reference

18 August 2017

1 reference

18 August 2017

PubMed publication ID

22682551

1 reference