(Q37132068)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Engineered soluble monomeric IgG1 CH3 domain: generation, mechanisms of function, and implications for design of biological therapeutics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Weizao Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Yang Feng

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Yanping Wang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Rui Gong

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Dimiter S Dimitrov

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

language of work or name

English

0 references

publication date

18 July 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

5 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

volume

288

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

issue

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

page(s)

25154-25164

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

cites work

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Soluble monomeric IgG1 Fc.

14 September 2017

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Stabilisation of the Fc fragment of human IgG1 by engineered intradomain disulfide bonds

14 September 2017

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Shortened engineered human antibody CH2 domains: increased stability and binding to the human neonatal Fc receptor

14 September 2017

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Design, expression and characterization of a soluble single-chain functional human neonatal Fc receptor

14 September 2017

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14 September 2017

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Engineered human antibody constant domains with increased stability

14 September 2017

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Therapeutic antibodies: current state and future trends--is a paradigm change coming soon?

14 September 2017

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Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers

14 September 2017

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Structure of an isolated unglycosylated antibody CH2 domain

14 September 2017

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Single-domain antibodies as building blocks for novel therapeutics

14 September 2017

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Fc-based cytokines : prospects for engineering superior therapeutics

14 September 2017

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FcRn: the neonatal Fc receptor comes of age.

14 September 2017

1 reference

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Potent antibody therapeutics by design

14 September 2017

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Engineered antibody fragments and the rise of single domains

14 September 2017

1 reference

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Folding mechanism of the CH2 antibody domain.

14 September 2017

1 reference

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Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor, FcRn.

14 September 2017

1 reference

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Domain antibodies: proteins for therapy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

Convergent solutions to binding at a protein-protein interface

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

Folding and association of the antibody domain CH3: prolyl isomerization preceeds dimerization

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

IgG-Fc-mediated effector functions: molecular definition of interaction sites for effector ligands and the role of glycosylation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

Core structure of gp41 from the HIV envelope glycoprotein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

The immunoglobulin fold. Structural classification, sequence patterns and common core

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

An Fc receptor structurally related to MHC class I antigens

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

Enhanced antibody half-life improves in vivo activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

Engineered human IgG antibodies with longer serum half-lives in primates

14 September 2017

1 reference

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Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR.

14 September 2017

1 reference

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Development trends for therapeutic antibody fragments

3 September 2018

1 reference

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Soluble Fc fusion proteins for biomedical research.

3 September 2018

1 reference

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Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

Folding and oxidation of the antibody domain C(H)3.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

Identification of critical IgG binding epitopes on the neonatal Fc receptor

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3757179

3 September 2018

The Immunoglobulin Fold

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23867459

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M113.484154

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

23867459

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23867459%20AND%20SRC:MED&resulttype=core&format=json